Methods and Feasibility Studies

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Articles published in 2026 in this theme: 172 (scroll down to load remaining articles)

2026

Diagram showing digestion, cellular processes (SOD, MDA), DNA, and aging.

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Evaluation of Vamana and Virechana as Interventions to Decelerate the Aging Process in Healthy Adult Volunteers: Protocol for an Exploratory Single-Arm Clinical Trial

Devipriya Soman, Ramesh NV, Pravith NK

JMIR Res Protoc 2026 (Sep 16); 15:e99146

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Person in bed having a telemedicine consultation with a doctor on a smartphone.

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Hybrid Telemedicine–House-Call Model for Pneumonia Management in North Texas: Retrospective Pilot Study

Raika Bourmand, Trevor Lee, Prabha Nair, Saji Pillai

JMIR Form Res 2026 (Sep 16); 10:e98767

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Three young people with laptops on a couch

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Improving Digital Measurement-Based Care Within Emerging Adult Mental Health Care Pathways: Protocol for a Co-Design Phase Embedded in a Multimethod Rapid Learning Health System Study

Geneca Henry, Leanne Stamp, Courtney Habina, Melanie Fersovitch, Karen Moskovic, Lia Norman, Karina Pintson, Melissa Potestio, Julia Hews-Girard, Haley M LaMonica, Frank Iorfino, Paul D Arnold, Gina Dimitropoulos

JMIR Res Protoc 2026 (Sep 11); 15:e93038

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Healthcare worker in PPE holds COVID-19 test tube

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Transdermal 17β-Estradiol for the Treatment of COVID-19: Protocol of an Early Terminated Phase 2 Randomized Controlled Trial

Adel Ganaw, Kayleigh Griffiths, Moad Ehfeda, Ashraf Elmalik, Manoj Varghese, Muna Al Maslamani, Prem Chandra, Hugh Montgomery, Melanie Madhani

JMIR Res Protoc 2026 (Sep 11); 15:e81541

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Researcher monitors a young athlete on exercise equipment with brain sensors.

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Feasibility and Acceptability of Useful Field of View Cognitive Training in Adolescent Athletes: Pilot Pre-Post Study

Elizabeth D Rosenthal, Tyler A Busch, Stacy J Suskauer, Beth S Slomine, Erika F Augustine, Emily R Akrong, Adrian M Svingos

JMIR Form Res 2026 (Sep 11); 10:e93778

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Intraoperative Ex Vivo Confocal Microscopy for Surgical Margin Assessment in Squamous Cell and Basal Cell Carcinoma (HISTOBLOC): Protocol for a Prospective Monocentric Pilot Study

Giacomo Gravante, Agnès Leroux, Christian Garbar, Louise Henry, Sophie Cortese, Emilie Beulque, Romina Mastronicola, Gilles Dolivet

JMIR Res Protoc 2026 (Sep 09); 15:e91436

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Development, Implementation, and Evaluation of a Prevention Model of Care in South West Queensland (Wellness my Way): Protocol for a Pilot Implementation Study

Claudia I Maddren, Clare Johnson, Tahlia Alsop, Madeline Forbes, Li Kheng Chai, Joanne Isbel, Kathy Morrow, Joanna Munro, Clare Murray, Shelley Peardon-Freeman, Claudia Regan-Knights, Helen Wassman, Sjaan R Gomersall

JMIR Res Protoc 2026 (Sep 03); 15:e98966

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Woman performing a COVID-19 rapid antigen test at home with a nasal swab.

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Repeat At-Home Saliva Collection to Measure Cortisol Awakening Response (CAR): Protocol Feasibility Study Among Black Women With Histories of Abuse

Kiyomi Tsuyuki, Marguerite B Lucea, Andrea N Cimino, Michael Killian, Christina J Catabay, Engle Abrams, Emmanuel Baffour-Siaw, Jacquelyn C Campbell, Douglas A Granger, Jamila K Stockman

Interact J Med Res 2026 (Sep 03); 15:e64150

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Young woman in headphones relaxes on a couch listening to music on her phone.

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Exploring the Role of a Noninvasive Audio-Based Therapeutic System for Pain and Symptom Relief: Single-Arm Exploratory Pilot Study

Lea Sacca, Isabella Abraham, Panagiota Kitsantas, Robert Sewak, Chengwu Yang, Timothy D Dye, Charles H Hennekens

JMIR Form Res 2026 (Sep 02); 10:e96015

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Refining and Assessing Gender-Tailored Group Therapy for Veteran Men With Military Sexual Trauma: Protocol for a Mixed Methods Study

Jonathan Yahalom, Erin P Finley, Sheila O'Brien, Brandon C Yarns, Lindsey L Monteith, Ariel J Lang, Alison B Hamilton

JMIR Res Protoc 2026 (Sep 01); 15:e105373

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Therapist massaging man's back with elbows on massage table

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Effectiveness of Tuina Therapy for Patients With Chronic Fatigue Syndrome: Protocol for a Multicenter, Randomized, Open-Label, Assessor-Blinded, Parallel-Group Clinical Trial

Jun Ren, Shoujian Wang, Sitong Fang, Shanda Xu, Chaoqun Xie, Ming Jin, Xingyu Zhou, Wu Li, Yan Zhao, Xingquan Wu, Cheng Wang, Yanguo Wang, Zhichao Gong, Jing Zhou, Junjie Yao, Xue Bai, Yu Wang, Min Fang, Lingjun Kong

JMIR Res Protoc 2026 (Sep 01); 15:e94022

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Man plays acoustic guitar and hand drum, creating music with rhythmic percussion.

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A Culturally Grounded Music-Based Intervention for Indigenous Older Adults in Long-Term Care: Protocol for a Mixed Methods Pilot Study

Ariel L Roddy, Katherine Mommaerts, Rebecca Maniglia, Juliette Roddy, Craig Yarbrough, Julie A Baldwin

JMIR Res Protoc 2026 (Sep 01); 15:e104850

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Doctor in scrubs touching a futuristic medical display showing brain and heart scans.

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Generative Artificial Intelligence for Qualitative Methods in Health Research: Rapid Review

Raúl D Gierbolini-Rivera, Milena Franco Silva, Alexandre Augusto de Paula da Silva, Ross C Brownson, Diana C Parra, Maura M Kepper, Amy A Eyler

J Med Internet Res 2026 (Aug 31); 28:e98551

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Woman doing physical therapy exercises via video call with a therapist.

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Remote Assessment of Physical Function and Physical Activity in Adults With Autism Spectrum Disorder: Protocol for Feasibility, Validity, and Reliability Study

Annabel Nunez-Gaunaurd, Melissa M Tovin, Melissa Hale, Tan Li, Anjana Bhat

JMIR Res Protoc 2026 (Aug 31); 15:e86020

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Mobile screener shows eligibility completed for study participation across US states.

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The Feasibility and Cost-Effectiveness of Tailored Social Media Advertising to Recruit Sexual and Gender Minority Adolescents in the Southern United States: Online Survey Study

Danielle Lambert, Nicole Luisi

JMIR Form Res 2026 (Aug 31); 10:e95006

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Close-up of an arm with an IV drip inserted into the vein, on a white medical sheet.

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Efficacy of Corticosteroid Therapy on Neurological Outcomes in Near-Hanging Patients With Altered Sensorium: Protocol for a Multicenter, Double-Blinded, Placebo-Controlled, Randomized Trial (CHANGING Trial)

Ramadoss Ramu, Dineshbabu Sekar, Aswin K, Ashish Behera, Manu Ayyan, Harichandra Kumar KT, Kavitha B, Mohan Kumar Hanumanthappa, Sree Naga Sowndary Rajendran

JMIR Res Protoc 2026 (Aug 25); 15:e100623

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Woman wearing VR headset relaxes on a blue couch, experiencing virtual reality

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Novel Virtual Reality Methods for the Treatment of Obsessive-Compulsive Disorder Using a User-Centered Design Approach: Focus Group Study

Michael Colman, Josie F A Millar, Bhagyashree Patil, Daniel J Finnegan, Mhairi Kristoffersen, Danae Stanton Fraser

JMIR XR Spatial Comput 2026 (Aug 20); 3:e92410

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Elderly care services: Online consultation, exercise, nutrition, and family support.

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Multicomponent Supportive-Educative mHealth Intervention for Self-Care Among Individuals With Osteoporosis in Thailand: Exploratory Pretest-Posttest Pilot Study

Natthida Pangutha, Sirinapha Jittimanee, Porramat Saksaen

JMIR Nursing 2026 (Aug 20); 9:e101025

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Exploring the Early-Life Microbiomes of Preterm Infants and Their Childhood Health Outcomes (The BLOOM Study): Protocol for a Prospective, Observational Cohort Study

Marie-Claire Arrieta, Andrea Guedez, Catherine Lebel, Emily M Mercer, Fatimoh Kasaba, Gerald F Giesbrecht, Hussein Zein, James D Kellner, Jumana Samara, Lara M Leijser, Laura Sycuro, Luis Murguía Favela, Michelle R Asbury, Thierry Lacaze-Masmonteil, Zahra Rangipour, Jessica Lee, Kelly McNagny, Leonora Hendson, Belal Alshaikh

JMIR Res Protoc 2026 (Aug 18); 15:e95658

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Young woman relaxing on a light gray couch, wearing a blue button-down shirt and jeans.

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Autonomic Nervous System Responses to Rest and Exertion Following Concussion (the Measuring ANSWERS Study): Protocol for a 2-Aim Cross-Sectional and Longitudinal Observational Study

Wesley R Cole, Aidan E Finegan, Adam W Kiefer, Aaron M Sinnott, Meredith Mann, Baiming Zou, Meisheng Xiao, Brittany L Heikke, Dominic Willoughby, Ryan MacPherson, Katelyn A Holter-Soerensen, Chloe D Campbell, Madison C Chandler, Johna K Register-Mihalik, Jason P Mihalik

JMIR Res Protoc 2026 (Aug 14); 15:e103400

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