Methods and Feasibility Studies

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Articles published in 2026 in this theme: 160 (scroll down to load remaining articles)

2026

Doctor in scrubs touching a futuristic medical display showing brain and heart scans.

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Generative Artificial Intelligence for Qualitative Methods in Health Research: Rapid Review

Raúl D Gierbolini-Rivera, Milena Franco Silva, Alexandre Augusto de Paula da Silva, Ross C Brownson, Diana C Parra, Maura M Kepper, Amy A Eyler

J Med Internet Res 2026 (Aug 31); 28:e98551

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Woman doing physical therapy exercises via video call with a therapist.

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Remote Assessment of Physical Function and Physical Activity in Adults With Autism Spectrum Disorder: Protocol for Feasibility, Validity, and Reliability Study

Annabel Nunez-Gaunaurd, Melissa M Tovin, Melissa Hale, Tan Li, Anjana Bhat

JMIR Res Protoc 2026 (Aug 31); 15:e86020

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Mobile screener shows eligibility completed for study participation across US states.

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The Feasibility and Cost-Effectiveness of Tailored Social Media Advertising to Recruit Sexual and Gender Minority Adolescents in the Southern United States: Online Survey Study

Danielle Lambert, Nicole Luisi

JMIR Form Res 2026 (Aug 31); 10:e95006

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Close-up of an arm with an IV drip inserted into the vein, on a white medical sheet.

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Efficacy of Corticosteroid Therapy on Neurological Outcomes in Near-Hanging Patients With Altered Sensorium: Protocol for a Multicenter, Double-Blinded, Placebo-Controlled, Randomized Trial (CHANGING Trial)

Ramadoss Ramu, Dineshbabu Sekar, Aswin K, Ashish Behera, Manu Ayyan, Harichandra Kumar KT, Kavitha B, Mohan Kumar Hanumanthappa, Sree Naga Sowndary Rajendran

JMIR Res Protoc 2026 (Aug 25); 15:e100623

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Woman wearing VR headset relaxes on a blue couch, experiencing virtual reality

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Novel Virtual Reality Methods for the Treatment of Obsessive-Compulsive Disorder Using a User-Centered Design Approach: Focus Group Study

Michael Colman, Josie F A Millar, Bhagyashree Patil, Daniel J Finnegan, Mhairi Kristoffersen, Danae Stanton Fraser

JMIR XR Spatial Comput 2026 (Aug 20); 3:e92410

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Elderly care services: Online consultation, exercise, nutrition, and family support.

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Multicomponent Supportive-Educative mHealth Intervention for Self-Care Among Individuals With Osteoporosis in Thailand: Exploratory Pretest-Posttest Pilot Study

Natthida Pangutha, Sirinapha Jittimanee, Porramat Saksaen

JMIR Nursing 2026 (Aug 20); 9:e101025

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Mother kissing sleeping baby with pacifier

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Exploring the Early-Life Microbiomes of Preterm Infants and Their Childhood Health Outcomes (The BLOOM Study): Protocol for a Prospective, Observational Cohort Study

Marie-Claire Arrieta, Andrea Guedez, Catherine Lebel, Emily M Mercer, Fatimoh Kasaba, Gerald F Giesbrecht, Hussein Zein, James D Kellner, Jumana Samara, Lara M Leijser, Laura Sycuro, Luis Murguía Favela, Michelle R Asbury, Thierry Lacaze-Masmonteil, Zahra Rangipour, Jessica Lee, Kelly McNagny, Leonora Hendson, Belal Alshaikh

JMIR Res Protoc 2026 (Aug 18); 15:e95658

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Young woman relaxing on a light gray couch, wearing a blue button-down shirt and jeans.

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Autonomic Nervous System Responses to Rest and Exertion Following Concussion (the Measuring ANSWERS Study): Protocol for a 2-Aim Cross-Sectional and Longitudinal Observational Study

Wesley R Cole, Aidan E Finegan, Adam W Kiefer, Aaron M Sinnott, Meredith Mann, Baiming Zou, Meisheng Xiao, Brittany L Heikke, Dominic Willoughby, Ryan MacPherson, Katelyn A Holter-Soerensen, Chloe D Campbell, Madison C Chandler, Johna K Register-Mihalik, Jason P Mihalik

JMIR Res Protoc 2026 (Aug 14); 15:e103400

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Doctor places a transcranial magnetic stimulation (TMS) coil on a patient's head.

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Effect of Low-Intensity Transcranial Focused Ultrasound Stimulation on Neuropathic Pain: Protocol for a Randomized, Single-Blind, Placebo-Controlled, 3-Arm, Parallel-Group Trial

Nobuhiko Mori, Yuhei Hoshikuma, Koichi Hosomi, Akihiro Yamamoto, Takeshi Shimizu, Hui Ming Khoo, Naoki Tani, Satoru Oshino, Haruhiko Kishima

JMIR Res Protoc 2026 (Aug 14); 15:e95379

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Toddler playing with wooden shape sorter and blocks

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Early Developmental Screening and a Home-Based Caregiver Intervention for Infants and Toddlers With Sickle Cell Disease: Protocol for a Prospective Mixed Methods Study

Catherine R Hoyt, Hunter G Moore, Ashley J Housten, Ana A Baumann, Allison A King

JMIR Res Protoc 2026 (Aug 14); 15:e104084

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Open book "Hayatin Esiriyiz" by Somerset Maugham held by hands in a library

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Feasibility of an Online Shared Reading Intervention in Survivors of Gynecological Cancer: Protocol for a Multiple-Baseline Single-Case Study

Sonia Tomescu-Stachie, Andrew Merwood, Katy Sivyer, Miznah Al-Abbadey, Sarah Kirby

JMIR Res Protoc 2026 (Aug 14); 15:e91900

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Electrodes on a person's wrist for nerve conduction studies

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Feasibility, Safety, and Preliminary Efficacy of Median Nerve Stimulation for Cognitive Dysfunction in Patients With Acute Traumatic Brain Injury: Study Protocol for a Pilot Randomized Controlled Trial

Yu Deng, Guoyi Gao, Liang Wu

JMIR Res Protoc 2026 (Aug 14); 15:e95327

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Two women, one in a wheelchair, talking in an office

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Effects of a Nurse-Led, Acceptance and Commitment–Based Palliative Intervention on the Psychospiritual Well-Being of Patients With Progressive Neurological Diseases: Protocol for a Mixed Methods Study

Lily Man Lee Chan, Wendy Wing Tak Lam, Koon Ho Chan, Shirley Yin Yu Pang, Man Auyeung, Jojo Yan Yan Kwok

JMIR Res Protoc 2026 (Aug 13); 15:e105727

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$Optical Quality of the Cornea After Orthokeratology Based on Total Corneal Refractive Power, Corneal Asphericity, and Epithelial Thickness: Protocol for a Prospective Quasi-Experimental Pre-Post Study$

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Optical Quality of the Cornea After Orthokeratology Based on Total Corneal Refractive Power, Corneal Asphericity, and Epithelial Thickness: Protocol for a Prospective Quasi-Experimental Pre-Post Study

José Licari, Alba Medico-Salsench, Laura Medina-Guijarro, César Villa-Collar, Cristina Rey-Reñones

JMIR Res Protoc 2026 (Aug 12); 15:e94476

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Diverse team collaborating around a table with charts and diagrams

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Codeveloping a Set of Quality of Care Indicators for People Living With Multiple Long-Term Conditions in Primary Care: Protocol for a Modified RAND/UCLA Study

Sara Tavares, Thomas Beaney, Arad Reisberg, Ania Henley, Angela Edwards, David Belsey, Laura Downey

JMIR Res Protoc 2026 (Aug 07); 15:e99217

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Woman with psoriasis preparing herbal remedies with mortar and pestle

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Efficacy and Safety of Integrated Traditional Chinese Medicine and Biologic Treatment in Moderate to Severe Atopic Dermatitis: Protocol for a Prospective Observational Real-World Study

Fanlingzi Shen, Ruiqi Cai, Jinrong Lu, Xiangjin Gao, Wencheng Jiang, Bin Li, Ruiping Wang

JMIR Res Protoc 2026 (Aug 07); 15:e96547

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Borang Persetujuan meal with chicken, rice, and soup

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A Digital Dietary Assessment Tool for a Multicultural Population (Intake24 Malaysia): Protocol for a Development and Validation Study

Nik Nur Izzati Nik Mohd Fakhruddin, Shaleen Tho Rajasegaram, Nurul Natasha Osman, Emma Foster, Choon Ming Ng, Nur Suraiya Abu Hassan Shaari, Tracy McCaffrey, Christopher Prawira, Patrick Olivier, Jessica Watterson, Amutha Ramadas

JMIR Res Protoc 2026 (Aug 04); 15:e90106

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Nurse uses stethoscope to check elderly man's heart in hospital room

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Psychosocial Burden and Supportive Care Needs of Informal Caregivers in Specialist Palliative Care: Protocol of a Multicenter Longitudinal Cohort Study to Identify Trajectories and Validate the Multidimensional Screening Tool CAREPAL-8

Clara Haufschild, Karin Oechsle, Antonia Zapf, Anne Daubmann, Philipp Weber, Holger Schulz, Anneke Ullrich

JMIR Res Protoc 2026 (Jul 31); 15:e78076

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Gaming setup: multiple monitors, tablet, keyboard, mouse, and game controllers

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Inclusive and Collaborative Exergame for Adults With Intellectual and Developmental Disabilities: Development and Usability Study

Chiara Piazzalunga, Samuele Ravazzani, Alberto Romano, Federica Maria Storti, Chiara Zelano, Emma Mencacci, Grazia Giana, Ottaviano Martinelli, Manuela Galli, Simona Ferrante

JMIR Serious Games 2026 (Jul 31); 14:e90156

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Yellow alarm clock on a white plate with fork and knife, symbolizing time-restricted eating

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Exploring the Feasibility, Acceptability, and Safety of a 4:3 Intermittent Fasting Weight Loss Program Among Stage I-III Breast Cancer Survivors With Overweight or Obesity: Protocol for a 6-Month Proof-of-Concept Feasibility Trial

Katrina M Oselinsky, Emily B Hill, Danielle M Ostendorf, Zhaoxing Pan, Kristen Bing, Liza T Wayland, Chloe Simpson, Kevin C Clark, Anaeli Sandoval, Elizabeth A Thomas, Ryan J Marker, Peter Kabos, Paul S MacLean, Victoria A Catenacci

JMIR Res Protoc 2026 (Jul 23); 15:e86281

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