JMIR Research Protocols

Conventional treatments have been frequently reported to offer partial relief for some individuals managing arthritis pain and related symptoms, leading many to consider alternative options, such as cannabis. Informed decision-making about cannabis use requires patients to weigh potential benefits and risks in light of their personal values and preferences.

Lung cancer screening (LCS) with low-dose computed tomography reduces mortality by up to 20%, yet uptake in the United States remains below 6% of eligible individuals. Factors contributing to low uptake include lack of awareness, eligibility confusion, stigma associated with smoking history, and nihilistic beliefs about outcomes. Stigma triggers shame-avoidance behaviors, nihilism undermines perceived screening benefit, and misinformation amplifies both by spreading inaccurate eligibility criteria and exaggerated harms. Social media increasingly shapes how individuals encounter health information, form risk perceptions, and make screening decisions. Because platform architectures differ in content modality, algorithmic curation, and user demographics, single-platform studies cannot reliably characterize the digital information environment or identify platform-specific intervention targets.

Research indicates that university students experience higher levels of stress, anxiety, and depression (SAD) than the general population. In Uganda, existing psychological interventions for addressing SAD among students are primarily delivered face to face, which limits effective diagnosis and treatment due to stigma, a shortage of counselors, and long waiting times, which contribute to significant unmet mental health needs. Consequently, there is an urgent need for innovative approaches to improve access to mental health services.

Assessing dental caries, sealants, and fluorosis is essential for public health surveillance, providing critical data to evaluate national prevention programs. Standard methods performed by dental professionals are often limited by affordability, accessibility, and scalability for both population-level and individualized assessments. Mobile health (mHealth) approaches to concurrently detect caries, sealants, and fluorosis have remained largely unexplored, especially at the population level.

Few manual chiropractic high velocity, low amplitude (HVLA) type shams have been validated in research. The proposed project is a randomized controlled trial (RCT) designed to assess a novel, full-spine, manual sham chiropractic maneuver and its blinding success.

Antenatal corticosteroid (ACS) treatment matures the fetal lung and reduces risks of neonatal morbidity and mortality in babies born preterm. However, ACS treatment also impacts the brain and stress regulatory systems, with increasing clinical evidence for adverse long-term impacts. Preclinical studies are important to investigate the mechanisms for these impacts.

Despite the growing demand for end-of-life home care, nursing educators responsible for on-the-job training face substantial barriers, such as time and geographical constraints, which limit their access to professional development. Collaborative online training programs offer a potential solution to these challenges.

Neonatal mortality remains a major public health challenge in low- and middle-income countries (LMICs), particularly in sub-Saharan Africa, where health systems often lack effective triage mechanisms to identify and prioritize high-risk neonates. Existing clinical tools frequently fail to support timely decision-making during the critical early postnatal period. A previous machine learning (ML)–based neonatal risk prediction model developed using multicountry LMIC datasets demonstrated high predictive accuracy for neonatal mortality in the Indian context, achieving an area under the curve above 0.80. The model incorporates 11 neonatal parameters assessed from delivery through day 2 of life, with birth weight identified as the strongest predictor.

Emergency department (ED) overcrowding threatens health care systems worldwide. This poses risks to patient safety, lowers quality of care, and reduces patient satisfaction. Patient input, defined as the caseload of patients presenting to the ED, is one of the factors contributing to overcrowding. Redirecting patients with nonurgent complaints to external health care services could help alleviate ED workload.

Attention deficit/hyperactivity disorder (ADHD) is the most prevalent neurodevelopmental disorder worldwide, affecting approximately 5%‐7% of school-aged children and 2%‐5% of adults worldwide. However, there is still no reliable diagnostic tool for it. The lack of specific biomarkers further complicates the accurate diagnosis of ADHD.

The identification of the methodological path followed by researchers in psychometric studies can contribute to maintaining the transparency and rigor necessary for the study.

Tunnel anastomosis is a novel anastomotic technique for digestive tract reconstruction following proximal gastrectomy. A previous retrospective study by our team demonstrated its favorable antireflux effect; therefore, we hypothesize that tunnel anastomosis is noninferior to double-tract jejunal interposition reconstruction in preventing postoperative reflux esophagitis, and we will conduct this prospective study to further validate this assumption.