JMIR Research Protocols

University students’ mental health problems are highly prevalent globally, which underlines the need for accessible and cost-effective mental health services in universities. Loneliness is a key risk factor for mental-health problems, and it disproportionately affects students from minority backgrounds. Therefore, addressing loneliness and fostering inclusion and equality can be crucial strategies for enhancing student wellbeing.

Mental disorders are highly prevalent and significantly impact individuals and society. Patients suffering from long-term, severe mental disorders with functional impairment and reduced quality of life often have a history of adolescent onset anxiety and depressive disorders. Despite the long-term cost to both the patients and society, studies examining the various treatment effect over time, across diagnoses and experienced for the patients are scarce.

The HIV prevalence among men who have sex with men (MSM) students in China is substantially higher than that in the general student population.However, targeted interventions for this vulnerable population remain limited. While digital technologies and peer-led approaches have shown promise in HIV prevention among MSM, their application in university settings is underexplored.

Heart failure (HF) is a global health challenge characterized by high mortality, morbidity, and economic burden. The development of digital health technologies offers promising tools for prevention, early detection, and management of HF, potentially improving prognosis and reducing costs. However, these innovations may also widen existing health disparities related to socioeconomic status, geography, and race or ethnicity.

The rising prevalence of mental health conditions continues to place significant pressure on general practitioners (GPs) and general practice. Despite their critical role in managing mental health conditions, GPs and practice staff face substantial barriers in providing effective mental health care, such as time and financial constraints. A new mental health model of care (Link-me+EMPHN) aimed at engaging and building capacity in GPs and practice staff for the provision of mental health services is being designed and implemented in a Primary Health region in Victoria, Australia.

Over 40% of Hispanics have below basic health literacy levels, significantly impacting their ability to manage chronic conditions such as type 2 diabetes (T2D). Chronic disease self-management, essential for improving adherence, is often hindered by modifiable factors such as health literacy. Ambulatory care clinical pharmacists, through comprehensive medication management (CMM), play a critical role in addressing these barriers, yet current methods for delivering CMM vary significantly, limiting effectiveness. Digital technology may offer significant potential for improving medication adherence, particularly among Hispanics using smartphones to seek health information.

Cytisinicline has proven to be an effective, efficient, and safe molecule in smoking cessation. However, the established 25-day regimen could be insufficient in a high percentage of smokers, so it is necessary to study maintained therapies of this drug.

The global burden of type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) continues to rise, with these conditions significantly increasing risks of cardiovascular disease, disability, and mortality. Traditional Chinese Medicine (TCM) syndrome differentiation, a cornerstone of TCM practice, guides diagnosis and treatment by identifying patterns of disharmony. However, large-scale studies investigating TCM syndrome patterns in T2DM comorbid with MetS remain scarce.

Many people are affected by mental disorders. A transdiagnostic symptom and risk factor for most mental disorders is repetitive negative thinking (RNT). Psychotherapy can reduce RNT, but most people in need either do not receive psychotherapy or face long waiting times. In addition, people at risk for developing mental disorders do not receive psychotherapy. Mobile health (mHealth) interventions could overcome treatment barriers and support people at risk.

Leptospirosis is the most common zoonotic cause of mortality, with most of its burden occurring in tropical regions and low-income countries. It is endemic in Southeast and South Asian nations. Leptospirosis outbreaks occur after natural disasters. In Malaysia, the e-notification system of the Communicable Diseases Control Information System recorded 5217 leptospirosis cases in 2019 with 32 fatalities. The incidence rate was 15.61 per 100,000 people. Male individuals comprised 67% of leptospirosis cases, while people aged 25 to 55 years accounted for 45% of the cases. Information and perception are crucial in influencing positive behavior. Nonetheless, information on urban and rural people’s knowledge, attitude, and practice (KAP) regarding the incidence of leptospirosis is limited.

Searching for transgender and gender diverse (TGD) references within large academic databases can be a challenging process, partly due to the dynamic and diverse definitions of words and terminologies used by multiple interest holders. Search hedges are preestablished search strings that aid in the efficacy of identifying and screening relevant articles. Validated search hedges focused on TGD people and topics will aid in identifying relevant literature.

Data collection is an essential aspect of clinical trials, as it forms the basis of the scientific analysis that evaluates the performance and safety of interventions. With the wide variety of digital data collection tools available, decision-makers responsible for choosing the appropriate tools for clinical trials must exercise caution. There are numerous challenges that could impact data collection, and careful selection is necessary to ensure the tools effectively support the trialClick or tap here to enter text. Therefore, an evidence-based framework is needed to support the selection of an appropriate digital data collection tool in clinical trials.