Non-Randomized Studies (funded, eHealth)

Using Implementation Science to Improve Health Care Access and Quality for People With Traumatic Brain Injury–Related Morbidity (I-HEAL): Protocol for a Translational Multiproject Program Award

Risa Nakase-Richardson, Jolie N Haun, Megan Moore, Jennifer Bogner, Jeanne M Hoffman, Kristen Dams-O'Connor, Jill Coulter, Tracy Kretzmer, Aaron M Martin, Marc A Silva, I-HEAL Consortium

JMIR Res Protoc 2026 (Mar 06); 15:e79738

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Acceptability of the Cardiff Online Cognitive Assessment for Clinical Screening of Patients With Psychosis: Protocol for a Mixed Methods Study

Amy J Lynham, Anthony Cope, Sarah Milosevic, Ian R Jones, James T R Walters

JMIR Res Protoc 2026 (Mar 03); 15:e84218

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Implementing an eHealth Model of Care for Pediatric Patients and Families at the End of Treatment for Acute Lymphoblastic Leukemia (EMERGE): Type 2 Nonrandomized Hybrid Implementation-Effectiveness Trial Study Protocol

Maria C McCarthy, Chris Williams, Michelle Tennant, Richard De Abreu Lourenco, Hannah Pring, Katie Moore, Jane Templeton, Ken Knight, Peter Downie, Stephen Hearps, Cinzia De Luca

JMIR Res Protoc 2026 (Feb 26); 15:e85901

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Identifying Predictors of Gambling Episodes and Craving Using Ecological Momentary Assessment and Smartwatch-Based Physiological Measures: Protocol for a Longitudinal Observational Study

Andreas Maximilian Meyer, Esther Kim, Hae Kook Lee, Gwanghyun Jo, Michael Patrick Schaub, Severin Haug

JMIR Res Protoc 2026 (Feb 19); 15:e82782

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Effectiveness and Cost-Effectiveness of Emergency Department–Based Violence Intervention Programs in the United Kingdom: Protocol for a Quasi-Experimental Study

Simon Moore, Sinead Brophy, Amrita Bandyopadhyay, Annemarie Newbury, Megan Hamilton, Adele Battaglia, Trudy Lowe, David O'Reilly, David Rawlinson, Lara Snowdon, Jonathan Shepherd, Vaseekaran Sivarajasingam, Alan Watkins, Simon Walker, Shainur Premji, Sophie Borgia, Henry Yeomans

JMIR Res Protoc 2026 (Feb 18); 15:e86247

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Evaluating an AI-Enabled Mobile Mental Health Monitoring Tool Among Family Caregivers of Adults Living With Cancer: Single-Arm Feasibility and Acceptability Trial Protocol

Chiara Acquati, Michael Aratow, Tahmida Nazreen, Arunima Bhattacharjee, Isabella K Marra, Ashley S Alexander

JMIR Res Protoc 2026 (Feb 12); 15:e83276

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Enhancing Caregivers’ Quality of Life Through a Web-Based Person-Centered Solution (TechQoL4Carers): Protocol for a Mixed Methods Pilot Trial

Betania Groba, Patricia Concheiro-Moscoso, María del Carmen Miranda-Duro, Manuel Lagos-Rodríguez, Javier Pereira, Laura Nieto-Riveiro

JMIR Res Protoc 2026 (Feb 05); 15:e86602

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Traditional Chinese Medicine Syndrome Differentiation of Adult Patients With Type 2 Diabetes and Metabolic Syndrome: Protocol for a Cross-Sectional Study

Jialing Zhang, Hoi Ki Wong, Zhilin Lin, Shuyan Zhong, Minxia Ma, Xuejiao Wang

JMIR Res Protoc 2026 (Jan 23); 15:e86217

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Using Alcohol and Sleep Sensors to Understand Blackout Risk in Young Adults’ Natural Settings (The Lights Out Study): Protocol for an Intensive Longitudinal Pilot Study

Veronica L Richards, Ashlea Braun, Michael R Sladek, Junru Zhao, Thad Leffingwell, Sydney Newell Chesebro, Julie M Croff

JMIR Res Protoc 2026 (Jan 21); 15:e83980

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A Virtual Living Lab Platform Codeveloped for Mental Health in Youth-Onset Type 2 Diabetes (BrightSpark Care Lab): Protocol for a Mixed Methods Study

Mandy M. Archibald, Brandy Wicklow, Elizabeth Sellers, Arlene Griffiths, Linda Diffey, Jonathan McGavock, Leslie E. Roos, Alexander M. Clark, Jennifer Lopez, Josephine Ho, Ernestine Ledoux, Gifty Dzorka, Shahina Parvin, Oluwatoyosi Fagbuyi, Allison Dart

JMIR Res Protoc 2026 (Jan 19); 15:e83865

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Smartphone-Based Physical Activity Program to Reduce “Chemo-Brain” Symptoms and Improve Health in Cancer Survivors With and Without Type 2 Diabetes: Protocol for a Single-Arm Pre-Post Pilot Trial

Zachary C Pope, Andriy Yabluchanskiy, Peter Mukli, Michael C Robertson, Jason A Oliver, Sarah J Borengasser, Meghan M Ratke, Jacob E Matney, Chris Mixon, Christina Henson, J Mikhail Kellawan

JMIR Res Protoc 2025 (Dec 10); 14:e79739

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Development of a Cocreated Perioperative Joint Replacement Digital Care Pathway to Improve Surgical Outcomes Following Joint Replacement: Protocol for a Mixed Methods Study

Adam I Semciw, Rebecca Jessup, Rachel Duckham, Swapna Gokhale, Hayley Gray, Emily C Bell, Stephen M Quick, Juliette Gentle, Uyen Phan, Katharine See, Rebecca Galea-O’Neill, James Boyd, Hazel Heng, Tracey Webster, Matthew G King

JMIR Res Protoc 2025 (Dec 04); 14:e85701

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Improving Work-Related Challenges in Psychiatric-Psychosomatic Clinics: Study Protocol for an Internet-Based Needs Assessment and Co-Design of a Training

Katharina Schiffer, Sonia Lippke

JMIR Res Protoc 2025 (Nov 25); 14:e78047

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A Novel Digital Platform to Support Child and Family Mental Health in Australia (Child and Family eHub): Protocol for a Mixed Methods Evaluation

Suzy Honisett, Raghu Lingam, Valsamma Eapen, Brian Oldenburg, Naomi Hackworth, Harriet Hiscock, George Charalambous, Lisa Minton, Glenn Pringle, Sue Woolfenden, Kim Dalziel, John Eastwood, Sharon Goldfeld

JMIR Res Protoc 2025 (Nov 13); 14:e72548

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Automated Personalized Goal Setting for Individual Exercise Behavior: Protocol for a Web-Based Adaptive Intervention Trial

Juan Carlos Caro, Phuong H Nguyen, Stefan Lipman

JMIR Res Protoc 2025 (Nov 12); 14:e73766

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Implementation, Experiences, Impact, and Costs of Artificial Intelligence in Chest Diagnostics: Protocol for a Mixed Methods Evaluation

Angus I G Ramsay, Chris Sherlaw-Johnson, Kevin Herbert, Stuti Bagri, Malina Bodea, Nadia Crellin, Holly Elphinstone, Amanda Halliday, Nina Hemmings, Rachel Lawrence, Cyril Lobont, Pei Li Ng, Joanne Lloyd, Efthalia Massou, Raj Mehta, Stephen Morris, Jenny Shand, Holly Walton, Naomi J Fulop

JMIR Res Protoc 2025 (Oct 31); 14:e81421

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Facial Feminization Surgery and Quality of Life in Transgender Women: Protocol for a Cohort Study

Francisca Donoso-Hofer, Rolando Carrasco Soto, Marco Cornejo Ovalle, Conchita Martín

JMIR Res Protoc 2025 (Oct 28); 14:e75065

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Implementation and Effectiveness of the Power Over Pain Portal for Patients Awaiting a Tertiary Care Consultation for Chronic Pain: Protocol for a Pilot, Prospective, Cohort, Mixed Methods Study

Amin Zahrai, Etienne J Bisson, Yaadwinder Shergill, Danielle Rice, Natalie Zur Nedden, Lynn Cooper, Daniel James, Josh A Rash, Rachael Bosma, Tim Ramsay, Patricia Poulin

JMIR Res Protoc 2025 (Sep 25); 14:e64801

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Clinical Performance Evaluation of an Artificial Intelligence–Based Tool for Predicting the Presence of Obstructive Coronary Artery Disease: Protocol for a Cohort Observational Study

Georgios Rampidis, Evangelos Logaras, Athanasios Samaras, Emmanouil S Rigas, Ilias Kyparissidis-Kokkinidis, Styliana Siakopoulou, Panagiotis-Emmanouil Kartsidis, Konstantinos Kouskouras, George Giannakoulas, Panagiotis Bamidis, Antonios Billis

JMIR Res Protoc 2025 (Sep 25); 14:e67697

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Clinical Utility of Early Intervention Including the 5-Step Precision Medicine Method in First-Episode Psychosis: Protocol for a Cohort Study With Nested Economic and Process Evaluations

Jesús Pérez, David Heredero Jung, Óscar Gonzalo, Belén García Berrocal, Carmen García Cerdán, Pablo Salas Aranda, Alejandro de la Sota Pérez, Sandra Milagros Lorenzo Hernández, Elena Marcos Vadillo, Rocío García García, Vanesa Berdión Marcos, Ana Maciá Casas, Belén Refoyo Matellán, Berta Bote Bonaechea, Llanyra García Ullán, Carolina Lorenzo Romo, Carmen Martín Gómez, Concha Turrión Gómez, María Isidoro García

JMIR Res Protoc 2025 (Sep 23); 14:e74408

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