This paper is in the following e-collection/theme issue:

RCTs - Protocols/Proposals (eHealth) (685) Depression and Mood Disorders; Suicide Prevention (1717) Cost-Effectiveness and Economics (363) Digital Mental Health Interventions, e-Mental Health and Cyberpsychology (2167) Web-based and Mobile Health Interventions (4081)

Published on in Vol 15 (2026)

This is a member publication of University College London (Jisc)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/80511, first published .
Clinical and Cost-Effectiveness of Blended Cognitive Behavioral Therapy or Psychodynamic Therapy Versus Face-to-Face Psychotherapy for Depression (BLENDED Study): Protocol for a Pragmatic, Multicenter, Assessor-Blinded Randomized Controlled Noninferiority Trial

Clinical and Cost-Effectiveness of Blended Cognitive Behavioral Therapy or Psychodynamic Therapy Versus Face-to-Face Psychotherapy for Depression (BLENDED Study): Protocol for a Pragmatic, Multicenter, Assessor-Blinded Randomized Controlled Noninferiority Trial

Clinical and Cost-Effectiveness of Blended Cognitive Behavioral Therapy or Psychodynamic Therapy Versus Face-to-Face Psychotherapy for Depression (BLENDED Study): Protocol for a Pragmatic, Multicenter, Assessor-Blinded Randomized Controlled Noninferiority Trial

Authors of this article:

Patrick Luyten1, 2 Author Orcid Image ;   Danielle Speybrouck2 Author Orcid Image ;   Peter Martin3 Author Orcid Image ;   Stephan Claes4 Author Orcid Image ;   Nick Midgley1 Author Orcid Image ;   Hester van Eeren5 Author Orcid Image ;   Jan van Busschbach5 Author Orcid Image ;   Eileen Tang2 Author Orcid Image
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