JMIR Research Protocols

Ongoing trials and protocols, grant proposals, and current methods and approaches. 

Editor-in-Chief:

Amy Schwartz, MSc, Ph.D., Scientific Editor at JMIR Publications, Ontario, Canada


Impact Factor 1.4 CiteScore 2.4

JMIR Research Protocols  (JRP, ISSN 1929-0748) is a unique journal indexed in PubMed, PubMed Central (PMC), MEDLINE, Sherpa Romeo, DOAJ, Scopus, Web of Science(WoS)/ESCI/SCIE, and EBSCO, publishing peer-reviewed, openly accessible research ideas and grant proposals, and study and trial protocols (also referred to as Registered Report Stage 1 papers). 

In 2024, JMIR Research Protocols received a Journal Impact Factor™ of 1.4 (5-Year Journal Impact Factor™: 1.5) according to the latest release of the Journal Citation Reports™ from Clarivate, 2024. 

With a CiteScore of 2.4, JMIR Research Protocols ranks in the 66th percentile (#211 of 636) as a Q2 journal in the field of General Medicine.

It should be stressed however that most authors do not publish their protocols for "impact" or citations, rather to document their ideas to how to design experiments, to document their successful grant proposals, or to publish (and maybe brag a little about) their already funded protocols (which do not require additional peer-review). We offer this platform for scientists to publish peer-reviewed protocols for a very low APF, and unfunded protocols for a reasonable fee that includes peer-review. 

While the original focus was on eHealth studies, JRP now publishes protocols and grant proposals in all areas of medicine, and their peer-review reports, if available (preliminary results from pilot studies, early results, and formative research should now be published in JMIR Formative Research).

JRP is fully open access, with full-text articles deposited in PubMed Central.

Why should I publish my protocol? 

  • JRP publishes research protocols, grant proposals, pilot/feasibility studies and early reports of ongoing and planned work that encourages collaboration and early feedback, and reduces duplication of effort.
  • JRP will be a valuable educational resource for researchers who want to learn about current research methodologies and how to write a winning grant proposal.
  • JRP creates an early scientific record for researchers who have developed novel methodologies, software, innovations or elaborate protocols.
  • JRP provides a "dry-run" for peer-review of the final results paper, and allows feedback/critique of the methods, often while they still can be fixed.
  • JRP enhances rigor and demonstrates to reviewers of subsequent results papers that authors followed and adhered to carefully developed and described a-priori methods, rather than fishing for P-values (HARKing).
  • JRP facilitates and guarantees subsequent publication of results demonstrating that the methodology has already been reviewed, and reduces the effort of writing up the results, as the protocol can be easily referenced.
  • JRP is compatible with the concept of "Registered Reports" and since May 2018, published protocols receive an International Registered Report Identifier (What is a Registered Report Identifier?) and acceptance of the subsequent results paper is "in principle" guaranteed in any JMIR journal and partner journals - see What is a Registered Report?. We assign an IRRID (International Registered Report Identifier) to each published protocol, faciliating the linking between protocol and final study, and also indicating that results papers of studies are also "in principle accepted" for subsequent publication in other JMIR journals (or other members of the IRRID Registry Network) as long as authors adhere to their original protocol - regardless of study results (even if they are negative), reducing publication bias in medicine.
  • Authors publishing their protocols in JRP will receive a 20% discount on the article processing fee if they publish their results in another journal of the JMIR journal family (for example, JMIR for e-health studies, i-JMR for others).

Need more reasons? Read the Knowledge Base article on "Why should I publish my protocol/grant proposal"!

 

Recent Articles

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RCTs - Protocols/Proposals (non-eHealth)

Working in an operating room (OR) is physically and mentally challenging: the operation itself demands the surgeon's full attention, while time and cost efficiency constraints, daily planning, and emergency care interfere with the procedure. Thus, multitasking becomes an integral surgical competence. This study aims to examine the effect of disruptions during surgery in a highly immersive virtual reality (IVR) operation environment combined with a virtual reality (VR) laparoscopy simulator.

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Non-Randomized Study Protocols and Methods (Non-eHealth)

Extracorporeal blood purification with CytoSorb has been increasingly used as an adjunctive therapy in several hyperinflammatory critical care conditions, as well as to remove elevated levels of myoglobin or bilirubin in patients with rhabdomyolysis or liver failure. Despite the increasing worldwide use of hemoadsorption, data from large international multicenter studies are still lacking.

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NIH mHealth - funded projects

Current programs to engage marginalized populations such as gay and bisexual individuals and other men who have sex with men (MSM) in HIV prevention interventions do not often reach all MSM who may benefit from them. To reduce the global burden of HIV, far-reaching strategies are needed to engage MSM in HIV prevention and treatment. Globally, including low- and middle-income countries, MSM are now widely using internet-based social and mobile technologies (SMTs; eg, dating apps, social media, and WhatsApp [Meta]), which provides an unprecedented opportunity to engage unreached and underserved groups, such as MSM for HIV prevention and care.

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RCTs - Protocols/Proposals (funded, already peer-reviewed, eHealth)

Type 2 diabetes (T2D) is preceded by prediabetes, and these conditions place a great burden on patients and society. These conditions are significantly associated with poor glycemic control, which is improved by resistance exercise. It has been suggested that resistance exercise should be performed with a high degree of effort to improve glucose metabolism, but this is associated with negative psychological responses that might lead to lower long-term adherence.

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Non-Randomized Study Protocols and Methods (Non-eHealth)

Prolonged systemic inflammation is recognized as a major contributor to the development of various chronic inflammatory diseases. Daily measurements of inflammatory biomarkers can significantly improve disease monitoring of systemic inflammation, thus contributing to reducing the burden on patients and the health care system. There exists, however, no scalable, cost-efficient, and noninvasive biomarker for remote assessment of systemic inflammation. To this end, we propose a novel, multimodal, and noninvasive approach for measuring inflammatory biomarkers.

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Systematic Review Protocols

Wearable technology is widely applied in performance monitoring, an integral part of sports and exercise sciences. The kick movement in soccer exemplifies a sports technique that could benefit from appropriate biomechanics assessment methodologies. However, the accuracy of wearables in quantifying soccer kick mechanics, particularly under field conditions, remains unclear.

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Systematic Review Protocols

Stress urinary incontinence (SUI), the most common form of urinary incontinence, is a condition that affects many women. It is characterized by involuntary urine leakage during activities that increase abdominal pressure, such as sneezing, coughing, or physical exertion, according to the International Continence Society. SUI affects patients’ quality of life and causes depression and emotional disorders, which negatively influences physical and mental health. The participants in the studies in this review comprised women with mild to moderate SUI, because there are more female patients than male patients, and most patients with severe SUI are treated surgically. Moreover, after retrieval, there were no systematic reviews or network meta-analyses (NMAs) of conservative treatments, such as electroacupuncture (EA), in women with mild to moderate SUI.

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Non-randomized Protocols and Methods (ehealth)

There is a growing prevalence of nonhealing wounds and chronic diseases in society, and there is an associated need for wound management solutions that include the use of telemedicine. A broad spectrum of factors influences the planning and execution of interventions within telemedicine in chronic wound management, spanning organizations, technologies, and individuals, including professionals and patients. The Telemedicine and Ambulatory Wound Care Team (TELE-AMBUS) project applies a whole-system research approach to account for this spectrum of factors.

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Participatory Research Protocols and Proposals

Clinical practice guidelines (CPGs) are designed to assist health care professionals in medical decision-making, but they often lack effective integration of shared decision-making (SDM) principles to reflect patient values and preferences, particularly in the context of preference-sensitive CPG recommendations. To address this shortcoming and foster SDM through CPGs, the integration of patient decision aids (PDAs) into CPGs has been proposed as an important strategy. However, methods for systematically identifying and prioritizing CPG recommendations relevant to SDM and related decision support tools are currently lacking.

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Systematic Review Protocols

Access to psychological health care is extremely difficult, especially for individuals with severely stigmatized disorders such as eating disorders (EDs). There has been an increase in children, adolescents, and adults with ED symptoms and ED, especially following the COVID-19 pandemic. Computer-based self-help platforms (± associated apps) allow people to bridge the treatment gap and receive support when in-person treatment is unavailable or not preferred.

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Scoping Review Protocols

Digital microscopy combined with artificial intelligence (AI) is increasingly being implemented in health care, predominantly in advanced laboratory settings. However, AI-supported digital microscopy could be especially advantageous in primary health care settings, since such methods could improve access to diagnostics via automation and lead to a decreased need for experts on site. To our knowledge, no scoping or systematic review had been published on the use of AI-supported digital microscopy within primary health care laboratories when this scoping review was initiated. A scoping review can guide future research by providing insights to help navigate the challenges of implementing these novel methods in primary health care laboratories.

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Systematic Review Protocols

Patellofemoral pain syndrome is a highly prevalent overuse knee injury in athletic populations associated with pain and functional limitations, exacerbated by activities such as running, pivoting, cycling, and jumping. Self-management programs empowering athletes to take an active role in controlling their symptoms for chronic musculoskeletal conditions such as patellofemoral pain syndrome have grown in popularity. However, the efficacy of self-management programs specifically for athletes with patellofemoral pain syndrome is unclear due to limited and heterogeneous evidence.

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Preprints Open for Peer-Review

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Open Peer Review Period:

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