Non-Randomized Studies (funded, non-eHealth)

Years in this theme: All years 2026 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

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Articles published in this theme: 203 (scroll down to load remaining articles)

2026

Woman in hospital waiting room, head in hands, looking distressed

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Risk Alert System to Facilitate Universal Suicide Risk Screening in Emergency Care: Protocol for a Prediction Model and Software Development Study Using a Co-Design Approach

Montserrat López-Fernández, Raúl Rodríguez Valderas, Ana Portillo-Van Diest, Gemma Vilagut, Miguel-Ángel Mayer, Montse Ferrer, Franco Amigo, Laura Latorre, Tatiana Leiss, Ángela Leis, Juan Manuel Ramírez-Anguita, Jorge Lemos Portela, Jordi Alonso, Manuel Pastor, Philippe Mortier

JMIR Res Protoc 2026 (Sep 16); 15:e100498

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Hands placing a face mask on the Earth, symbolizing global health.

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The Effect of Tuberculosis and HIV on the Epidemiological, Clinical, Virological, and Immunological Trajectory of COVID-19: Protocol for a Prospective Case-Ascertained and Surveillance Study

Azaria Diergaardt, Etuhole Iipumbu, Sibongile Netha, Pieter Steenkamp, Libertina Shiweva, Balladiah Kizito, Gunar Günther, Emmanuel Nepolo, Tadesse Woldetsadik, Stefan Niemann, Chawangwa Modongo, Mareli Claassens

JMIR Res Protoc 2026 (Sep 15); 15:e79438

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Man plays acoustic guitar and hand drum, creating music with rhythmic percussion.

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A Culturally Grounded Music-Based Intervention for Indigenous Older Adults in Long-Term Care: Protocol for a Mixed Methods Pilot Study

Ariel L Roddy, Katherine Mommaerts, Rebecca Maniglia, Juliette Roddy, Craig Yarbrough, Julie A Baldwin

JMIR Res Protoc 2026 (Sep 01); 15:e104850

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Health worker takes blood pressure of a woman in a rural setting.

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Community-Based Hypertension Screening to Prevent Stroke in Underserved Urban Neighborhoods in French Guiana: Protocol for a Quasi-Experimental Study

Devi Rita Rochemont, Mayka Mergeay-Fabre, Aniza Fahrasmane, Claire Boceno, Mathieu Nacher

JMIR Res Protoc 2026 (Aug 27); 15:e89318

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Pregnant woman with ultrasound, DNA, and fetal development visualization

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Prediction of Pregnancy Complications Related to Placental Dysfunction: Protocol for a Prospective Cohort Study (Placental Health Study)

Luhao Han, Hasini Rathnayake, Olivia Holland, Cristiane de Freitas Paganoti, Conrado Sávio Ragazini, Elsa Suk Fan Chan, Sally Mahler, Carman Wing Sze Lai, Daniel Lorber Rolnik, Anthony Perkins, David Ellwood, Sailesh Kumar, Fabricio Da Silva Costa

JMIR Res Protoc 2026 (Aug 25); 15:e95231

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Family discusses concerns with a therapist in a counseling session.

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Mental Readiness of Clients and Families Before Discharge From Drug Rehabilitation: Protocol for a Qualitative Study

Eny Purwandari, Rini Lestari, Aad Satria Permadi

JMIR Res Protoc 2026 (Aug 18); 15:e89763

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Young woman relaxing on a light gray couch, wearing a blue button-down shirt and jeans.

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Autonomic Nervous System Responses to Rest and Exertion Following Concussion (the Measuring ANSWERS Study): Protocol for a 2-Aim Cross-Sectional and Longitudinal Observational Study

Wesley R Cole, Aidan E Finegan, Adam W Kiefer, Aaron M Sinnott, Meredith Mann, Baiming Zou, Meisheng Xiao, Brittany L Heikke, Dominic Willoughby, Ryan MacPherson, Katelyn A Holter-Soerensen, Chloe D Campbell, Madison C Chandler, Johna K Register-Mihalik, Jason P Mihalik

JMIR Res Protoc 2026 (Aug 14); 15:e103400

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Toddler playing with wooden shape sorter and blocks

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Early Developmental Screening and a Home-Based Caregiver Intervention for Infants and Toddlers With Sickle Cell Disease: Protocol for a Prospective Mixed Methods Study

Catherine R Hoyt, Hunter G Moore, Ashley J Housten, Ana A Baumann, Allison A King

JMIR Res Protoc 2026 (Aug 14); 15:e104084

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Caregiver in blue gloves holding an elderly patient's hand in a wheelchair.

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Co-Designing a Care Coordination Intervention for People With Motor Neuron Disease: Protocol for a Mixed Methods Study

Bryony Waters-Harvey, Kathleen Kane, Alys Wyn Griffiths, Grahame Smith, Clare M Bartlett, Lise Sproson, Sandra Smith, Jennie Starkey, Amy Clift, Theocharis Stavroulakis, Esther Hobson, Emily Mayberry, Alicia O'Cathain, Caroline Bidder, Katherine Kennedy, Jane Gibson, Christopher McDermott, Liam Knox

JMIR Res Protoc 2026 (Aug 04); 15:e96327

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Students at a Health Promoting School engage in activities, with a circular diagram of school well-being.

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A Health Promoting School Intervention in 10th Grade (“My Life – I Decide”): Protocol for a Pragmatic Controlled Trial

Nanna Wurr Stjernqvist, Anne Timm, Anders Blædel Hansen, Mads Bølling, Tilde Skjærlund Jensen, Helle Stuart, Charlotte Demant Klinker

JMIR Res Protoc 2026 (Jul 17); 15:e100471

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Four diverse young adults high-fiving in a modern office space

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Evaluation of 24-Month Effects of the Close to Home Program on Youth Sexual and Dating Violence Across 22 Communities in California: Protocol for a Quasi-Experimental Cluster-Matched Control Trial

Emma C Jackson, Sabrina C Boyce, Ricardo Vera Monroy, Holly (Shakya) Baker, Jay G Silverman

JMIR Res Protoc 2026 (Jul 15); 15:e81249

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Four diverse children with backpacks walking on a sidewalk

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Evaluating the Effectiveness of the School-Based Sustainable Innovation for Children Transporting Actively Intervention: Protocol for an Age-Cohort Study

Hanna Forsberg, Anna-Karin Lindqvist, Stina Rutberg, Palma Chillón, Veronica Sjöberg, Annie Palstam

JMIR Res Protoc 2026 (Jun 05); 15:e92946

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Man in burgundy sweater looking out window on a rainy day

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Modeling Negative Symptom Domain Neurobiology: Protocol for an Observational, Transdiagnostic, Translational Study

Dan Cătălin Oprea, Ilinca Untu, Diana-Sabina Vieru, Camelia Dascălu, Helene Speyer, Cristina Dobre, Ohad Green, Romeo Petru Dobrin, Michael Davidson, Jonathan Rabinowitz, Bogdan Ionel Tamba

JMIR Res Protoc 2026 (May 18); 15:e92115

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Smartphone displaying a TAND Toolkit app with a timeline of a child's journey

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Closing the Gap to Interventions for Tuberous Sclerosis Complex–Associated Neuropsychiatric Disorders (TAND): Protocol for a Longitudinal Study of TAND Severity, Predictors, and Caregiver Well-Being (TANDem-2)

Petrus J de Vries, Nola Chambers, Erin Campbell, Lucas Gutierrez-Lafrentz, Tosca-Marie Heunis, Liezl Schlebusch, Guillaume Beaure d'Augères, Stacey Bissell, Anna Byars, Jamie Capal, Laís Cardozo, Sebastian Cukier, Peter Davis, Naomi Beth Epstein, Carla Fladrowski, Jennifer Flinn, Tanjala Gipson, Sarah Louise Goy, John Christopher Kingswood, Darcy Krueger, Francesca Little, Sugnet Lubbe, Rebecca Mitchell, Micaela Rozenberg, Mustafa Sahin, Mitchell Silva, Catherine Smith, Shoba Srivastava, Megumi Takei, Agnies van Eeghen, Mary Vasseghi, Jan-Paul Wagenaar, Robert Waltereit, Liesbeth De Waele, Anna C Jansen

JMIR Res Protoc 2026 (May 05); 15:e91726

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Diverse group of college students walking on campus with books

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Establishment, Implementation, and Impacts of the Observatory on Student Mental Health in Higher Education in Quebec, Canada: Protocol for a Mixed Methods Research Program

Julie Lane, Benjamin Gallais, François Lauzier-Jobin, Sèverine Lanoue, Félix Guay-Dufour, Rémi Paré-Beauchemin, Rachel Guertin, Christiane Bergeron-Leclerc, Saliha Ziam, Marie-Claude Lallier Beaudoin, Martine Shareck, Véronique Boudreault, Marie-Ève Langelier, Steve Geoffrion, Nancy Beauregard, Bianca B-Lamoureux, Magaly Brodeur, Esther McSween-Cadieux, Audrey Dupuis, Jonathan Smith, Isabelle Thibault, Noémie Beauregard

JMIR Res Protoc 2026 (Apr 22); 15:e83225

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Family on a video call with a doctor for telehealth.

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Care Pathways and Patient Experiences Among Patients With Post COVID-19 Condition: Study Protocol for a Mixed-Methods Study in Germany

Daniela Gesell, Paula Lienesch, Yanyan Shi, Ralf Strobl, Martin Tauscher, Roman Gerlach, Eva Grill, Daniela Koller

JMIR Res Protoc 2026 (Apr 22); 15:e91976

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Young girl in blue hospital gown holding a healthcare worker's arm

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Pediatric Emergency Agitation Care Enhancement: Protocol for a Prospective Mixed Methods Study

Lillian Klein, Wendy Pomerantz, Teresa Pestian, Yin Zhang, Drew Barzman, Lisa Vaughn, Nancy Daraiseh, Ryan Siders, Holly Hanson, Bijan Ketabchi, Lynn Babcock

JMIR Res Protoc 2026 (Apr 21); 15:e92452

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Teddy bear reading a book to a child in a cozy room

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Locus-Coeruleus Norepinephrine Functioning as a Predictor of Childhood Mental Health (LOCUS-MENTAL): Protocol for a Longitudinal Study

Iskra Todorova, Paula R Neubauer, Nico Bast

JMIR Res Protoc 2026 (Apr 20); 15:e89237

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Rural African village with thatched roofs and mountains in background

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The Gut Bacterial Resistome in the First Two Years of Life: Protocol for a Longitudinal Observational Birth Cohort Study

Justine Fri, Tjale Cloupas Mahopo, Lufuno Grace Mavhandu-Ramarumo, Idris Njanje, Pascal Obong Bessong, Microbiome and Antimicrobial Resistance Collaborators

JMIR Res Protoc 2026 (Apr 15); 15:e86058

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Doctor holding patient's hands in a gesture of care and empathy.

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Taunakitanga Takitini, Reframing Self-Management Support for All in Aotearoa New Zealand: Protocol for a Participatory Case Study Program of Research

Leigh Hale, Bernadette Huatau Jones, Ofa Dewes, Shirley Keown, Brigit Mirfin-Veitch, Amanda Wilkinson, Donna Keen, Pauline Norris, Eileen McKinlay, Meredith Perry, Kate Diesfeld, Henrietta Trip, Tristram Ingham, Nancy Longnecker, Roberta Francis Watene

JMIR Res Protoc 2026 (Apr 08); 15:e89658

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