RCTs - Protocols/Proposals (eHealth)

Articles published in 2026-rcts-protocols-and-proposals-ehealth in this theme: 52 (scroll down to load remaining articles)

2026

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Implementation of Mobile-Based Programs for Alcohol Cessation in the Treatment of Alcohol-associated Liver Disease: Protocol for a Type 1 Hybrid Implementation-Effectiveness Trial

Cecilia He, Jordan Edwards, Linda S Park, Mallory Herzog, Xiang Li, Alice Pulvermacher, Marlon P Mundt, Randall Brown, Jessica Mellinger, Andrew Quanbeck

JMIR Res Protoc 2026 (May 29); 15:e94231

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An e-Coaching Intervention for Family Carers to Enhance Well-Being and Resilience Through Self-Help Strategies: Protocol for a Randomized Controlled Trial

Tom Chun Wai Tsoi, Kenneth Yu Hon Kwok, Wai Sze Chan, Vera Mun Yu Tang, Tarani Chandola, Jianchao Quan, Chun Yu Yu, Vivian Weiqun Lou

JMIR Res Protoc 2026 (May 27); 15:e75944

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Digital Cognitive Behavioral Therapy for Insomnia Versus Sleep Hygiene Education for Prevention of Perinatal Depression: Protocol for a Randomized Clinical Trial

Jennifer N Felder, Patricia J Moran, Bernadette McClelland, Richelle Mah, Candance Sorensen, Carolyn Ponting, Nasim C Sobhani, John Neuhaus, Andrew Krystal, Rachel Manber

JMIR Res Protoc 2026 (May 26); 15:e90969

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Virtual Reality for Preoperative Anxiety in Patients Undergoing Odontectomy Under General Anesthesia: Protocol for a Randomized Controlled Trial

Saptiadi Oktora, Harmas Yazid Yusuf, Eriska Riyanti, Firdaus Hariri

JMIR Res Protoc 2026 (May 26); 15:e94535

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Development of a Digital Multimodal Pain Intervention (CHRONIC): Protocol for a Randomized Controlled Trial Study

Gentian Bunjaku, Lena Fellbaum, Aaron Laufhütte, Tanja Zimmermann

JMIR Res Protoc 2026 (May 26); 15:e84437

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A Compassion-Focused Online Single-Session Intervention to Reduce Academic Stress in University Students: Protocol for a Randomized Controlled Trial

Clara Wehlage, Sofija Zivanovic, Helen Koechlin, Nathalie Sarah Schicktanz, Olivia Bolt, Dorothée Bentz

JMIR Res Protoc 2026 (May 22); 15:e83850

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Effect of a Personalized Mobile Health Intervention Using Artificial Intelligence (the WARIFA App) Versus a Nonpersonalized Intervention on User-Defined Objectives, Healthy Lifestyles, and Management of Type 1 Diabetes (T1D): Protocol for a Randomized Controlled Trial

Carmelo Betancort Acosta, Garlene Zamora Zamorano, María Luisa Álvarez Malé, Lilisbeth Perestelo-Perez, Alezandra Torres Castaño, Marit B Veierød, Kristina Reyes Suárez, Alejandro Déniz García, Eirik Årsand, Inger Torhild Gram, Maja-Lisa Løchen, Cristina Soguero-Ruiz, André Henriksen, Antonio J Rodríguez Almeida, Miroslav Muzny, Reetta Välimäki, Thomas Schopf, Himar Fabelo, Conceição Granja, Ana M Wägner

JMIR Res Protoc 2026 (May 22); 15:e84510

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Comparing Real and Virtual Nature Exposure on Cognition, Well-Being, and Brain Activity in Adults With and Without Attention-Deficit/Hyperactivity Disorder: Protocol for a Randomized Experimental Study

Tianran Zhang, Dimitrios Adamis, Natasha Langan, Martin O’Neill

JMIR Res Protoc 2026 (May 22); 15:e82970

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Mobile Health Technology for Personalized Tobacco Cessation Support in Laos (Project Support Laos): Protocol for a Randomized Controlled Trial

Thanh Cong Bui, Phonepadith Xangsayarath, Phayvanh Keopraseuth, Khatthanaphone Phandouangsy, Khamsing Keothongkou, Vangnakhone Dittaphong, Cate Moriasi, Khue-Tu T Doan, Shweta Kulkarni, Chanthavy Soulaphy, Dalouny Xayavong, Viengphone Sangxayalath, Khanittha Sengdara, Michael S Businelle, Summer G Frank-Pearce, Jennifer I Vidrine, Damon J Vidrine

JMIR Res Protoc 2026 (May 21); 15:e89916

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Using Facebook to Improve Participation in Colorectal Cancer Screening: Protocol for a Cluster Randomized Controlled Trial

Arlinda Ruco, Natalie Baker, Melissa Howse, Anne Sorvari, Jenna Jacobson, Diego Llovet, Jill Tinmouth, Rahim Moineddin, Nancy Noel Baxter

JMIR Res Protoc 2026 (May 14); 15:e86829

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Effects of Remotely Supervised Home-Based High-Speed Bodyweight Resistance Training on Bradykinesia in Individuals With Parkinson Disease: Protocol for a Randomized Controlled Trial

Poliana do Amaral Yamaguchi Benfica, Aline Alvim Scianni, Carolina Luisa de Almeida Soares, Isabel Lopes Ribeiro, Pedro Vitor Casado, Christina Danielli Coelho de Morais Faria

JMIR Res Protoc 2026 (May 04); 15:e84689

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Machine Learning Prediction and Reducing Overdoses With Electronic Health Record Nudges (mPROVEN) in the Primary Care Setting: Protocol for a Cluster Randomized Controlled Trial

Walid F Gellad, Yi-Fan Chen, Tae Woo Park, Qingnan Yang, Jonathan D Arnold, Courtney C Kuza, Stephanie N Fedro-Byrom, Julie Diiulio, Laura G Militello, Michelle Whitlock, Eugene M Sadhu, Shyam Visweswaran, Michael J Fine, Kaleab Z Abebe, Katie J Suda, Wei-Hsuan Lo-Ciganic

JMIR Res Protoc 2026 (May 04); 15:e94007

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Effectiveness and Feasibility of Self-Monitoring for Weight Management in Individuals With Mental Disorders Using Digital Intervention: Protocol for a Stepped-Wedge Cluster Randomized Trial (“SWIM” Study)

Jiamiao Wu, Jinjie Xu, Jingyi Bi, Xuequan Zhu, Le Xiao

JMIR Res Protoc 2026 (Apr 27); 15:e78420

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Social Media–Based Professional Intervention vs Resource Provision for Youth With Suicidal Ideation or Behavior: Protocol for a Randomized Controlled Trial

Margot Morgiève, Leloup Manon, Anne-Christine Lesniak, Laurine Rougegrez, Nathalie Rigbourg, Vincent Jardon, Marielle Wathelet, Anne-Laure Demarty, Karim Dahache, Alain Duhamel, Thomas Delbarre, Pierre Grandgenèvre, Charles-Edouard Notredame

JMIR Res Protoc 2026 (Apr 24); 15:e83303

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The Effect of an Educational Intervention on the Knowledge and Self-Care Skills of Adult Patients With Venous Leg Ulcers: Protocol for a Randomized Controlled Trial

Cristina Canova, Jessica Scappin, Maria Vittoria Chiaruttini, Laura Tasson, Flavia Masiero, Claudia Varagnolo, Matteo Martinato

JMIR Res Protoc 2026 (Apr 21); 15:e84211

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Overcoming the HIV Pre-Exposure Prophylaxis Uptake Barrier With A Health Action Process Approach and Conditional Economic Incentives Among Men Who Have Sex With Men in 3 Chinese Cities: Protocol for a Randomized Controlled Trial

Hao Lin, Mojun Ni, Chun Chang, Feng Sun, Jinghua Li, Omar Galárraga, Phoenix Kit-Han Mo, Wangnan Cao

JMIR Res Protoc 2026 (Apr 20); 15:e82123

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Implementation of a Cancer Navigation Intervention for Newly Diagnosed Survivors of Breast Cancer: Protocol for a Randomized Controlled Trial

Melba Sheila D'Souza, Ruby Gidda, Michelle Smith, Arati Swaminadhan, Amy Jean Strank, Ashwin Nairy

JMIR Res Protoc 2026 (Apr 20); 15:e85820

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Combining Digital Cognitive Behavioral Therapy With Mindfulness Training for Binge Eating Disorder: Protocol for a Feasibility Trial

Margaret Sala, Corey Roos, Dante Ascarrunz, Casey M Stern, Jonathan Bricker, Jonathan M Feldman, Cheri Levinson, Mihaela Aslan, Jennifer L Hay, Hedy Kober

JMIR Res Protoc 2026 (Apr 17); 15:e91761

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Feasibility of Internet-Based Mind-Body Training for Adults With Subjective Cognitive Decline: Protocol for a Randomized Controlled Trial

Ruchika S Prakash, Madhura Phansikar, Megan E Fisher, Sarah Dove, Rebecca Andridge, Doug Scharre, Kathy D Wright, Elizabeth Head, Claire O'Callaghan, Quinn K Meyerson, Elizabeth J Duraney, Matthew Schroeder, Niyathi Chakrapani, Elise K Grant, Tyreek Jones, James Teng, Michael Esterman, Joshua M Smyth, Thomas Gregoire, Rond Malhas

JMIR Res Protoc 2026 (Apr 13); 15:e86276

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A Mobile Self-Assessment and Referral Platform for Family Caregivers of Individuals With Alzheimer Disease and Related Dementias: Protocol for a Pilot Randomized Controlled Trial

Francesca Falzarano, Annabelle Greenfield, Hannah Mason, Katerina Bumbalova, Elizabeth Rojas, Aleksandar Bumbalov

JMIR Res Protoc 2026 (Apr 01); 15:e90244

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