RCTs - Protocols/Proposals (eHealth)

Articles published in 2026 in this theme: 74 (scroll down to load remaining articles)

2026

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Therapist-Facilitated Virtual Reality Intervention for Social Anxiety Among Youth: Protocol for a Randomized Controlled Trial

Yi Zhou Wang, Ming Tak Hue, Kung Wong Lau, De Hui Zhou, Siu Man Ng, Xue Weng

JMIR Res Protoc 2026 (Aug 11); 15:e86937

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HABIT-ILE@home for Children With Bilateral Cerebral Palsy: Protocol for Noninferiority and Superiority Randomized Controlled Trials

Zélie Rosselli, Merlin Somville, Edouard Ducoffre, Carlyne Arnould, Yannick Bleyenheuft, Geoffroy Saussez

JMIR Res Protoc 2026 (Aug 11); 15:e89872

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Effectiveness and Cost-Effectiveness of the Tankevirus and Grubl Mental Health Apps Compared With a Placebo App—Mental Health Intervention With Digital Applications (MIND-APP): Protocol for a Randomized Controlled Researcher-Blinded Trial

Kim Rand, Julia Menichetti, Torbjørn Wisløff, Hanne Helene Brorson

JMIR Res Protoc 2026 (Aug 10); 15:e84096

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Graded Exercise Therapy and Cognitive Behavioral Therapy for Fatigue in Patients With Breast Cancer: Protocol for a Randomized Controlled Pilot Study

Joanna Rui En Fong, Pei Ling Tan, Michelle Tian Nee Chow, Whee Sze Ong, Irene Teo, Ryan Shea Ying Cong Tan, Mothi Babu Ramalingam

JMIR Res Protoc 2026 (Aug 07); 15:e91330

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Structured Online Support to Inform and Assist Antidepressant Deprescribing in Primary Care (WiserAD Tool): Protocol for a Pragmatic Randomized Controlled Trial

Catherine Kaylor-Hughes, Amy Coe, Patty Chondros, Konstancja Densley, Susan Fletcher, Mary-Lou Chatterton, Daniel Hoyer, Timothy Chen, Chee Ng, Derelie Mangin, Tony Kendrick, Zoe Allnutt, Jane Gunn AO

JMIR Res Protoc 2026 (Aug 07); 15:e81858

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Efficacy of Cognitive Behavioral Therapy–Based Digital Therapeutics for Substance Use Disorder: Protocol for a Randomized Controlled Trial

Yong Chan Jeong, Sang-Kyu Lee, Haemin Seo, Boung Chul Lee, Tae Kyung Lee, Do hoon Kwon, Ye-Jin Jang, Jae-Kyoung Shin, Byoung-Kwon Lee, Ha Yeong Choi

JMIR Res Protoc 2026 (Aug 07); 15:e85458

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Implementation and Evaluation of an AI-Assisted Telerehabilitation System for Postdischarge Continuation of Rehabilitative Care: Protocol for a Randomized Controlled Trial

Charmaine You Mei Tan, Xin Yi Seah, Sharna Si Ying Seah, Xin Hui Loh, Wendelynn Hui Ping Chua, Olivia Jiawen Xia, Chitra D/O Chandran, Hozaidah Hosain, Wenjing Qiu, Kevin Chong, Bee Choo Tai, Lian Leng Low

JMIR Res Protoc 2026 (Aug 05); 15:e78400

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Effectiveness of Virtual Reality–Based Simulation Training as a Supplement to Traditional Simulation Training for Improving Neonatal Resuscitation Performance Among Doctors and Nurses in Denmark: Protocol for a Multicenter Randomized Controlled Trial

Hanna Rahimi, Anja Poulsen, Jette Led Sørensen, Ida Madeline Hoffmann, Amalie Middelboe Sohlin, Line Klingen Gjærde, Stine Lund

JMIR Res Protoc 2026 (Jul 24); 15:e93439

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Efficacy of a Mobile Health App in Promoting Breastfeeding and Young Child Feeding Practices in Pakistan: Protocol for a Randomized Controlled Trial

Rozina Nuruddin, Rehama Iqbal, Nuruddin Mohammed, Khadija Barkat Ali Vadsaria, Sidrah Nausheen, Saleem Sayani, Iqbal Azam

JMIR Res Protoc 2026 (Jul 20); 15:e93181

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Blended Trauma-Focused Cognitive Behavioral Therapy With Compassion for Adolescents With Posttraumatic Stress Disorder: Protocol for a Pilot Randomized Controlled Trial in Northern Sweden

Linda Wallin, Carl Göran Svedin, Inga Dennhag

JMIR Res Protoc 2026 (Jul 15); 15:e92270

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AI-Assisted Chest X-Ray Interpretation in Resource-Limited Settings: LuAna Stepped-Wedge Trial Protocol

Maria Carolina Bueno da Silva, Paula Bresciani M de Andrade, Henrique Min Ho Lee, Pedro Vinicius Alves Silva, Ana Cristina Ferreira, Cintia Pereira Kuss, Maria Gabriela de Almeida Rodrigues, Guilherme Alberto Sousa Ribeiro, Thiago Fellipe Ortiz Camargo, William Yang Chen Fan, Pedro Vieira Santana Netto, Giovanna de Souza Mendes, Gilberto Szarf, Rafael Maffei Loureiro, Ary Serpa Neto, Joselisa Péres Queiroz de Paiva, Jaqueline Driemeyer Correia Horvath

JMIR Res Protoc 2026 (Jul 13); 15:e88626

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Using Ecological Momentary Assessment, Geolocation Tracking, and Neuroimaging to Assess Effects of Tobacco Retail Exposure on Smoking Behavior: Protocol for the GeoSmoking Study

Nicole Cooper, Benjamin Muzekari, Anthony Resnick, Alexandra M Paul, Omaya Torres-Grillo, Farah Sayed, Elizabeth Beard, Melis E Cakar, Jose Carreras-Tartak, Susan Hao, Bradley Mattan, Mary Andrews, Darin Johnson, Christian Benitez, Emily Zhou, Christin Scholz, Ian Barnett, Michael Fichman, Lisa Henriksen, Thomas R Kirchner, David M Lydon-Staley, Andrew A Strasser, Emily B Falk

JMIR Res Protoc 2026 (Jul 10); 15:e89627

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Artificial Intelligence–Assisted Screening for Patients With Diabetic Retinopathy and Age-Related Macular Degeneration in Family Medicine and Geriatric and Gerontology Care: Protocol for a Pragmatic Randomized Clinical Trial

Bo-I Kuo, Ting-Ann Wang, Teresa Cheng-Chieh Chu, Ding-Cheng Chan, Shao-Yi Cheng, Chia-Ti Tsai, Chu-Lin Tsai, Yi-Chia Lee, Wei-Li Chen, Chiuan-Jung Chen, John Tayu Lee, Chia-Ying Tsai, Patrick Yan-Tyng Liu, Chi-Yang Chang, Chia-Ter Chao, Jia-Horng Kao, Yi-Ting Hsieh, the Collaborators of AI Ophthalmology Research Group

JMIR Res Protoc 2026 (Jul 06); 15:e91699

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The Effects of Neuromuscular Electrical Stimulation and Leap Motion–Based Exercises on Hand Function Parameters in Children With Cerebral Palsy: Study Protocol for a Randomized Controlled Trial

Hande Özlü Erdoğan, Gülay Aras Bayram, Sema Targıt Akbaşak, Devrim Tarakcı

JMIR Res Protoc 2026 (Jul 03); 15:e94705

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Clinical Dose-Response of Inflammation Formula Number 1 Granules Versus Traditional Decoction in the Treatment of Patients With Mild to Moderate Atopic Dermatitis: Protocol for a Multicenter Randomized Controlled Trial

Ding Li, Xin Ma, Chuanbing Xu, Xin Li, Yang Meng, Wencheng Jiang, Guangpu Luo, Yanping Liu, Fanlingzi Shen, Xiangjin Gao, Ruiping Wang, Bin Li

JMIR Res Protoc 2026 (Jul 03); 15:e96094

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Navigation System–Assisted vs Freehand Cannulated Screw Fixation for Femoral Neck Fractures: Protocol for a Multicenter Randomized Controlled Trial

Meng Li, Dake Tong, Meng Cheng, Jiantao Li, Fang Ji, Wei Zhang

JMIR Res Protoc 2026 (Jun 23); 15:e88180

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Production of a Health Awareness Video on Precautionary Measures Against Respiratory Infectious Diseases for Public Transportation Drivers: Protocol for a Scoping Review, a Delphi Study, and a Randomized Controlled Trial

Mahmoud Salam, Sleiman El Dhaybe, Leen Ghannam, Maya Serhan, Mira Hassan

JMIR Res Protoc 2026 (Jun 19); 15:e89474

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Design, Development, and Validation of a Chatbot to Support Health Care Professionals Experiencing Workplace Aggression: Protocol for a Mixed Methods Study

Alba García-Viola, Verónica V Márquez-Hernández, José Miguel Garrido-Molina, Alfredo Alcayde-García, Mª Carmen Rodríguez-García

JMIR Res Protoc 2026 (Jun 18); 15:e92511

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Advancing Discussions Using a Video-Based Support Tool About End-of-Life Care (ADVISE): Protocol for a Single-Center Randomized Controlled Trial

Mokunfayo O Fajemisin, Ashna S Karpe, Stephanie Martinez Ugarte, Martin L Blakely, Gina Khraish, Shreyans Sanghvi, Jessica L Lee, Lillian S Kao, Thaddeus J Puzio

JMIR Res Protoc 2026 (Jun 18); 15:e87690

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Comparing 2-Hz and 100-Hz Electroacupuncture for Postoperative Musculoskeletal Pain: Protocol for a 2 × 2 Prospective Randomized Crossover Trial

Jeong Hwan Park, Hyeong Joon Jun, Young-Eun Kim, Sanghun Lee, Daehyeok Kim, Sunmi Choi

JMIR Res Protoc 2026 (Jun 16); 15:e91706

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