RCTs - Protocols/Proposals (eHealth)

Articles published in 2025 in this theme: 127 (scroll down to load remaining articles)

2025

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Using a Heuristic Tool to Improve Symptom Self-Management in Adolescents and Young Adults With Cancer: Protocol for a Randomized Controlled Trial

Suzanne Ameringer, Grace Hodges, R K Elswick Jr, Lauri Linder, Catherine Fiona Macpherson, Kristin Stegenga

JMIR Res Protoc 2025 (Dec 24); 14:e76667

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Virtual, Nurse-Led Early Primary Palliative Care Intervention (ELICIT) for Community-Dwelling Older Adults With Cognitive Impairment: Protocol for a Randomized Controlled Trial

Vyjeyanthi S Periyakoil, Charles Von Gunten, Helena Kraemer

JMIR Res Protoc 2025 (Dec 24); 14:e75082

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Efficacy of Artificial Intelligence–Assisted Appliances in the Selection of Tooth Shade: Protocol for an Observational Study

Namita Zilpilwar, Sharayu Nimonkar, Surekha Godbole, Vikram Belkhode

JMIR Res Protoc 2025 (Dec 22); 14:e68160

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App-Based Myofunctional Therapy to Improve Adherence and Outcomes of Mandibular Advancement Devices in Moderate Obstructive Sleep Apnea: Multicenter Randomized Trial Protocol

Juan Antonio Ibañez-Rodríguez, Carlos O'Connor-Reina, Ricardo Lucas, Laura Rodriguez-Alcala, Eduardo Correa, Jose Maria Ignacio, Patricia Fernandez-Sanjuan, Peter Baptista, Guillermo Plaza

JMIR Res Protoc 2025 (Dec 19); 14:e80521

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Wearable Continuous Vital Sign Monitoring Study (WARD-AMS) to Detect Clinical Deterioration in Postoperative General Surgery Patients: Protocol for a Randomized Controlled Trial

Jasjit Syan, Meera Joshi, John Beard, Jonah Attebery, Fu Siong Ng, Sadia Khan

JMIR Res Protoc 2025 (Dec 19); 14:e81558

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Evaluating AI-Generated Podcasts Versus Traditional Reading for Learning From Medical Articles: Protocol for a Mixed-Design Study Among Resident Physicians

Matthias Stadler, Constanze Richters, Martin R Fischer, Fabian Hutmacher

JMIR Res Protoc 2025 (Dec 12); 14:e78505

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Effectiveness of a Cardiovascular Management System on Triple Risk Factor Control in High-Risk Older Adults: Protocol for a Randomized Controlled Trial

Yan Wang, Lei Su, Jingyi Xiao, Xiaoying He, Hua Hong, Lin Xu

JMIR Res Protoc 2025 (Dec 09); 14:e84428

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Evaluation of the BALANCE Program as a Digital Therapeutic Solution for Type 2 Diabetes Management: Protocol for a Prospective Lifestyle Intervention Study

Jane Tey, Joshua Lam, Chee Kwang Yung, Musjarena Abd Mulok, Nurshazwani Mat Salleh, Alice Moi Ling Yong, Yvonne Lee, Pui Lin Chong

JMIR Res Protoc 2025 (Dec 08); 14:e73964

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Digital Training for Mental Health Promotion in Young People With Climate Change-Related Distress: Protocol for a Feasibility Randomized Controlled Trial

Leonie Fleck, Henrik Wasmus, Frederike Schirmbeck, Claudia de Freitas, Raquel Teixeira, Liuska Sanna, Anne Marijn de Graaff, Manuela De Allegri, Hoa Thi Nguyen, Jan R Boehnke, Evaldas Kazlauskas, Wietse Tol, Ulrich Reininghaus

JMIR Res Protoc 2025 (Dec 05); 14:e77764

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The Scale-Up of a Digital Health Intervention (Healthy Beginnings for HNEKids) Targeting the First 2000 Days: Protocol for a Randomized Controlled Trial

Alison L Brown, Nayerra Hudson, Jacklyn Jackson, Jessica Pinfold, Luke Wolfenden, Nicole Nathan, Rebecca Sewter, Sienna Kavalec, Lynda Davies, Sarah Young, Hannah McCormick, Sonya Stanley, Tessa Delaney, Christophe Lecathelinais, Paul Craven, Sinead Redman, Emma Cushing, Nguyet de Mello, Karen Lee, Rachel Sutherland

JMIR Res Protoc 2025 (Dec 05); 14:e81390

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Gamified Optimized Diabetes Management With Artificial Intelligence–Powered Rural Telehealth Intervention (GODART): Protocol for an Optimization Pilot and Feasibility Trial

Tapan Mehta, Tejossy John, Aseel El Zein, Victoria Faught, Tanjila Nawshin, Tejaswini Subhash Chilke, Caroline W Cohen, Andrea Cherrington, Mohanraj Thirumalai

JMIR Res Protoc 2025 (Dec 05); 14:e70271

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Efficacy of FiberMore, an AI-Based mHealth Intervention to Increase Dietary Fiber Intake Among Type 2 Diabetes Patients: Protocol for a Pilot Randomized Controlled Trial

Wei Thing Sze, Kayo Waki, Daniel Lane, Kyohei Hasegawa, Ryohei Nakada, Shuya Iwata, Yuexiang Ji, Akihiro Isogawa, Tomohisa Aoyama, Kana Miyake, Yuri Kadowaki, Tomoya Kawaguchi, Yoshinori Matsuo, Kengo Miyoshi, Nagisa Ishibashi, Gotaro Toda, Saori Kameda, Masaki Igarashi, Masaki Tanaka, Toshimasa Yamauchi, Masaomi Nangaku

JMIR Res Protoc 2025 (Dec 04); 14:e78019

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A Mobile Game Intervention for Young Persons Living With HIV and Depression in Nigeria: Protocol for a Pilot Randomized Controlled Trial

Caleb Eliazer, Temitope Omotosho, Kehinde M Kuti, Leslie J Pierce, Dalton Gray, Carolyn M Audet, Olutosin Awolude, Oye Gureje, Bibilola Oladeji, Aima A Ahonkhai

JMIR Res Protoc 2025 (Dec 03); 14:e74199

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Effect of SMS Reminders, Telephone Calls, and Transport Incentives on Enhancing the Completion of Tuberculosis Diagnosis and Initiation of Treatment for Diagnosed Patients: Protocol for a Randomized Controlled Trial

Rebecca Nuwematsiko, Noah Kiwanuka, Lynn Atuyambe, Irene Wobusobozi, Vicent Kasiita, Samuel Kagongwe, Ronald Ssenyonga, Joan Nakayaga Kalyango, Victoria Nankabirwa, Esther Buregyeya

JMIR Res Protoc 2025 (Nov 25); 14:e70325

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Sitting Baduanjin Combined With Acupoint Massage on Frailty in Patients Undergoing Maintenance Hemodialysis: Protocol for a Randomized Controlled Trial

Wanyu Zhao, Shurong Zhang, Hongmei Xie, Junhong Hou, Fang Wang, Jing Shi, Shasha Luo

JMIR Res Protoc 2025 (Nov 21); 14:e72352

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Layperson-Friendly AI Translation of Medical Documents to Improve Doctor–Patient Communication: Protocols for the AI-INFOCARE and AI-MEDTALK Randomized Controlled Trials

Elida Hasani, Sven Richter, Tareq Adnan Juratli, Clara Helene Buszello, Markus Georg Prem, Sophia Willkommen, Sahr Sandi-Gahun, Ilker Yasin Eyüpoglu, Witold Henryk Polanski

JMIR Res Protoc 2025 (Nov 21); 14:e77204

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Effectiveness of Cognitive Rehabilitation on Cognition and Quality of Life in Chemotherapy-Induced Cognitive Impairment: Protocol for a Randomized Control Trial

Gayatri Surendra Kaple, Moh’d Irshad Qureshi, Raghumahanti Raghuveer, Sharath Hullumani

JMIR Res Protoc 2025 (Nov 20); 14:e66011

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Changing the Perceived Pain Intensity in Populations With Spinal Cord Injury and With Health Disparities (HAPPINESS): Protocol for a Feasibility Study

Ann Van de Winckel, Lin Zhang, Kelvin O Lim, Leslie R Morse, Brianna Woodliff, Gladys Maestre, Kelsey Baker

JMIR Res Protoc 2025 (Nov 19); 14:e82431

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Integration of Mindfulness and Acupuncture After Spine Surgery: Protocol for a Randomized Acceptability and Feasibility Trial

Trevor A Lentz, Laura S Porter, Lewis McGarvey, Cassandra Rhodes, Brett Rocos, Tina Gremore, Emily K Reinke, Stephanie A Eucker, Cynthia L Green, Emily Poehlein, Austin Dixon, Michelle Mill, Suzanne Finley, Christine M Goertz

JMIR Res Protoc 2025 (Nov 17); 14:e77236

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Evaluating the Impact of Telehealth Exercise Prehabilitation on Cardiometabolic Health in Bariatric Surgery Candidates: Protocol for the BARI-Prehab Randomized Controlled Trial

Belinda Jayne Durey, Alison M Coates, Kade Davison, Brett Tarca, Jessica Mok, Chetan D Parmar, Naiara Fernandez-Munoz, Katarina Burton, Nicholas Tetlow, Amy Louise Dewar, Mariam Olaide Adeleke, Zoe Lugg, Jack Colbert, Daniel S Martin

JMIR Res Protoc 2025 (Nov 13); 14:e77538

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