RCTs - Protocols/Proposals (eHealth)

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Articles published in 2026 in this theme: 85 (scroll down to load remaining articles)

2026

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Reminder Strategies to Improve Meal-Logging Adherence: Protocol for a Microrandomized Trial

Magdalena Fuchs, Victoria Brügger, Qiuhan Jin, Benjamin Wirth, Stefan Bilz, Florian von Wangenheim, Michael Brändle, Tobias Kowatsch, Mia Jovanova

JMIR Res Protoc 2026 (Oct 05); 15:e100239

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Woman with short blonde hair smiling while looking at her pink smartphone

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Cocreation of a Digital Psychological Intervention to Improve Mental Health Among Survivors of Breast Cancer (SerenApp): Protocol for a Usability and Pilot Randomized Controlled Trial

Irene Zarcos-Pedrinaci, Vanesa Ramos-García, María Padilla-Ruíz, Francisco Rivas-Ruíz, Antoni Baena, Santiago Galán, Andrea Duarte-Díaz, Lilisbeth Perestelo-Pérez, Yolanda Álvarez Pérez, Cristina Valcárcel-Nazco, Maximino Redondo Bautista, Esperanza Varela-Moreno

JMIR Res Protoc 2026 (Sep 30); 15:e87151

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Woman uses phone app tracking energy, sleep, and activity.

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Evaluation of a Mental Health Care App–Based Fatigue Management Program for Patients With Inflammatory Bowel Disease in Remission: Protocol for a Randomized Controlled Trial

Makoto Tanaka, Sayaka Wakai, Kayoko Sakagami, Aki Kawakami, Hikari N Takashina, Jeongae Kang, Masakazu Nagahori, Hiroaki Ito

JMIR Res Protoc 2026 (Sep 28); 15:e96593

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DIPAR Digital Diabetes Patient Reminder Tool on a smartphone screen

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The Digital Diabetes Patient Reminder Tool for Adults With Type 2 Diabetes: Protocol for a Proof-of-Concept Randomized Controlled Trial

Barbara Annancy, Steve Van den Bulck, Steffen Fieuws, Laura Van den Mooter, Roman Vangoitsenhoven, Geert Goderis

JMIR Res Protoc 2026 (Sep 22); 15:e93006

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Woman using a smartphone with a colorful app interface showing "Help" and "Thinking" sections.

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A Culturally Adapted Smoking Cessation App (IndigeQuit) for American Indian and Alaska Native Adults: Protocol for a Randomized Clinical Trial

Jonathan B Bricker, Margarita Santiago-Torres, Brianna M Sullivan, Kristin E Mull, Hershel W Clark, Chase Kornacki, Trivia Afraid of Lightning-Craddock, Dean S Seneca, Crystal M Stanford, Sierra L Wilcox, Patricia Nez Henderson, Lonnie Nelson

JMIR Res Protoc 2026 (Sep 02); 15:e102675

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Two women in a living room, one wearing a VR headset and gesturing, the other watching

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One-Session Versus Three-Sessions of Virtual Reality Exposure Therapy for Public Speaking Anxiety: Protocol of a Randomized Controlled Trial

Goda Gegieckaitė, Olga Zamalijeva, Karolina Petraškaitė, Egle Nagevice, Philip Lindner, Per Carlbring, Tom Van Daele, Gerhard Andersson, Jonas Eimontas

JMIR Res Protoc 2026 (Aug 25); 15:e89612

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Patient stands on pressure plate for gait analysis while technician monitors computer.

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Efficacy of Mulligan Mobilization, Maitland Mobilization, High-Velocity Thrust, and Muscle Energy Technique for Pain, Disability, and Center-of-Gravity Displacement in Patients With Sacroiliac Joint Dysfunction: Protocol for a Randomized Controlled Trial

Neha Chitale, Lajwanti Lalwani

JMIR Res Protoc 2026 (Aug 21); 15:e87715

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Elderly woman in hospital bed with oxygen mask and beanie

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Effect of Remote Vital Signs Monitoring in People Receiving Long-Term Oxygen Therapy: Protocol for a Randomized Controlled Trial

Elinny Raissa Moreira dos Reis, Gabriela Martins Alencar, Amanda Maria Schneider, Mari Claussen Tani Fernandes, Juliana de Melo Batista dos Santos, Celso Ricardo Fernandes Carvalho

JMIR Res Protoc 2026 (Aug 21); 15:e93352

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Man in a mask on a stationary bike during a cardiopulmonary exercise test.

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The Effects of AI-Guided Exercise and a Smart Ring on Arterial Stiffness: Protocol for a Randomized Controlled Trial

Heikki Pentikäinen, Sofia Strömmer, Drake Caraker, Julia Kosonen, Aleksi Rantanen, Saila Hiltunen, Pirjo Komulainen, Heidi Similä, Massimiliano de Zambotti, Kai Savonen, Pauli Ohukainen

JMIR Res Protoc 2026 (Aug 21); 15:e98213

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Father checks young son's back for rash or irritation, indoors.

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Remote Interdisciplinary Care for Atopic Dermatitis Using a Digital Care Concept (ADCompanion): Protocol for a Multicenter Randomized Trial

Stephanie Dramburg, Camilo José Hernandez Toro, Josephine Telschow, Susanne Abraham, Meslina Almaci, Anna Behringer, Simone Christel, Angela Cornelius, Janina Feustel, Sascha Fischer, Isabelle Gloeyer, Nadia Günther, Katharina Hagemeister, Eckard Hamelmann, Leonard Harries, Annice Heratizadeh, Nora Knappe, Sonja Lämmel, Eva Moennig, Irena Neustädter, Christina Pham, Laura Rechtien, Thomas Reinhold, Christina Schnopp, Christina Schorlemer, Lukas Sollfrank, Sophie Spies, Kristina Stamos, Michael Sticherling, Piera Tierno, Marion Trentmann, Marie-Therese Unterweger, Christian Vogelberg, Hanna Winkler, Margitta Worm, Mehrak Yoosefi, Ulrike Grittner

JMIR Res Protoc 2026 (Aug 20); 15:e88025

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Elderly man with hand on chest, discussing health concerns with a doctor

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Protocol for a Sequential Multiple Assignment Randomized Trial to Improve Physical Activity and Diet Quality in Survivors of Cancer

Eric J Chow, Ethan D Lee, Marie Hershberger, Kari Jenssen, Chongzhi Di, David R Doody, Bridget Hogue, Jason A Mendoza, Tammy M Muller, Jeannette M Schenk, Karen L Syrjala, Yueqi Xu, Jean Yi, Ying-Qi Zhao, Gregory T Armstrong, Marian L Neuhouser, Kevin C Oeffinger

JMIR Res Protoc 2026 (Aug 13); 15:e104572

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Diners enjoy Hong Kong-style cafe cuisine at a bustling cha chaan teng.

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Therapist-Facilitated Virtual Reality Intervention for Social Anxiety Among Youth: Protocol for a Randomized Controlled Trial

Yi Zhou Wang, Ming Tak Hue, Kung Wong Lau, De Hui Zhou, Siu Man Ng, Xue Weng

JMIR Res Protoc 2026 (Aug 11); 15:e86937

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Boy playing a racing game on a touch screen table with colorful controllers.

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HABIT-ILE@home for Children With Bilateral Cerebral Palsy: Protocol for Noninferiority and Superiority Randomized Controlled Trials

Zélie Rosselli, Merlin Somville, Edouard Ducoffre, Carlyne Arnould, Yannick Bleyenheuft, Geoffroy Saussez

JMIR Res Protoc 2026 (Aug 11); 15:e89872

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Young woman looking stressed while reading on her phone on a sofa

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Effectiveness and Cost-Effectiveness of the Tankevirus and Grubl Mental Health Apps Compared With a Placebo App—Mental Health Intervention With Digital Applications (MIND-APP): Protocol for a Randomized Controlled Researcher-Blinded Trial

Kim Rand, Julia Menichetti, Torbjørn Wisløff, Hanne Helene Brorson

JMIR Res Protoc 2026 (Aug 10); 15:e84096

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Woman in headscarf on telehealth call with doctor on laptop

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Graded Exercise Therapy and Cognitive Behavioral Therapy for Fatigue in Patients With Breast Cancer: Protocol for a Randomized Controlled Pilot Study

Joanna Rui En Fong, Pei Ling Tan, Michelle Tian Nee Chow, Whee Sze Ong, Irene Teo, Ryan Shea Ying Cong Tan, Mothi Babu Ramalingam

JMIR Res Protoc 2026 (Aug 07); 15:e91330

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Doctor in white coat checks phone while holding a coffee cup at desk.

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Efficacy of Cognitive Behavioral Therapy–Based Digital Therapeutics for Substance Use Disorder: Protocol for a Randomized Controlled Trial

Yong Chan Jeong, Sang-Kyu Lee, Haemin Seo, Boung Chul Lee, Tae Kyung Lee, Do hoon Kwon, Ye-Jin Jang, Jae-Kyoung Shin, Byoung-Kwon Lee, Ha Yeong Choi

JMIR Res Protoc 2026 (Aug 07); 15:e85458

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Two women collaborating on a laptop, discussing a project.

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Structured Online Support to Inform and Assist Antidepressant Deprescribing in Primary Care (WiserAD Tool): Protocol for a Pragmatic Randomized Controlled Trial

Catherine Kaylor-Hughes, Amy Coe, Patty Chondros, Konstancja Densley, Susan Fletcher, Mary-Lou Chatterton, Daniel Hoyer, Timothy Chen, Chee Ng, Derelie Mangin, Tony Kendrick, Zoe Allnutt, Jane Gunn AO

JMIR Res Protoc 2026 (Aug 07); 15:e81858

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Elderly woman with gray hair and glasses smiling at her smartphone

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Implementation and Evaluation of an AI-Assisted Telerehabilitation System for Postdischarge Continuation of Rehabilitative Care: Protocol for a Randomized Controlled Trial

Charmaine You Mei Tan, Xin Yi Seah, Sharna Si Ying Seah, Xin Hui Loh, Wendelynn Hui Ping Chua, Olivia Jiawen Xia, Chitra D/O Chandran, Hozaidah Hosain, Wenjing Qiu, Kevin Chong, Bee Choo Tai, Lian Leng Low

JMIR Res Protoc 2026 (Aug 05); 15:e78400

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Doctor using VR headset to interact with medical data

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Effectiveness of Virtual Reality–Based Simulation Training as a Supplement to Traditional Simulation Training for Improving Neonatal Resuscitation Performance Among Doctors and Nurses in Denmark: Protocol for a Multicenter Randomized Controlled Trial

Hanna Rahimi, Anja Poulsen, Jette Led Sørensen, Ida Madeline Hoffmann, Amalie Middelboe Sohlin, Line Klingen Gjærde, Stine Lund

JMIR Res Protoc 2026 (Jul 24); 15:e93439

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Woman shows phone screen with QR code and baby's foot

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Efficacy of a Mobile Health App in Promoting Breastfeeding and Young Child Feeding Practices in Pakistan: Protocol for a Randomized Controlled Trial

Rozina Nuruddin, Rehama Iqbal, Nuruddin Mohammed, Khadija Barkat Ali Vadsaria, Sidrah Nausheen, Saleem Sayani, Iqbal Azam

JMIR Res Protoc 2026 (Jul 20); 15:e93181

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