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Non-Randomized Study Protocols and Methods (Non-eHealth) (1300) Obstetrics, Gynecology, and Reproductive Medicine (439) Methods and Feasibility Studies (781) Chronic Conditions (572) Microbial genomics and metagenomics (22)

Published on in Vol 15 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/102121, first published .
Woman with PCOS holding a calendar showing delayed periods, with symptoms listed.

Effects of Lactobacillus crispatus–Containing Probiotics and Metformin on Insulin Resistance, Inflammation, and Gut Microbiome in Polycystic Ovary Syndrome: Protocol for an Open-Label Randomized Controlled Trial

Effects of Lactobacillus crispatus–Containing Probiotics and Metformin on Insulin Resistance, Inflammation, and Gut Microbiome in Polycystic Ovary Syndrome: Protocol for an Open-Label Randomized Controlled Trial

Authors of this article:

Bhuvaneswari H1 Author Orcid Image ;   Suchanda Sahu1 Author Orcid Image ;   Deepthy Balakrishnan2 Author Orcid Image ;   Balamurugan Ramadass1 Author Orcid Image
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Bhuvaneswari H   1 * , MBBS ;   Suchanda Sahu   1 * , MBBS, MD, PGDFM ;   Deepthy Balakrishnan   2 , MS ;   Balamurugan Ramadass   1 , PhD

1 Department of Biochemistry, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India

2 Department of Obstretics and Gynaecology, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India

*these authors contributed equally

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