RCTs - Protocols/Proposals (non-eHealth)

Articles published in 2026 in this theme: 92 (scroll down to load remaining articles)

2026

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Efficacy of Liuzijue in Improving Respiratory Muscle Dysfunction in Chronic Obstructive Pulmonary Disease: Protocol for a Randomized Controlled Trial

Yiting Ni, Wei Feng, Wangtao Cai, Yuxin Sun, Min Cao, Juhan Chen, Jian Li

JMIR Res Protoc 2026 (Aug 10); 15:e91283

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Integrated Traditional Chinese and Western Medicine for Chronic Spontaneous Urticaria: Protocol for a Trials Within Cohorts Study

Linhao Li, Sihan Wang, Jiale Chen, Xiaojie Ding, Yifei Wang, Fei Guo, Xiaoying Sun, Liu Liu, Xin Li

JMIR Res Protoc 2026 (Aug 04); 15:e88251

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Development and Validation of a Culturally Competent Care Module and Its Effect on Nurses’ Cultural Competence and Patient Satisfaction: Protocol for a Randomized Controlled Trial in a Tertiary Care Hospital in India

Ligy C Ittup, Ranjana Sharma

JMIR Res Protoc 2026 (Jul 29); 15:e84015

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Feasibility, Acceptability, and Test Performance of Point-of-Care Nucleic Acid Tests for HIV Testing and Viral Load Monitoring in the United States: Prospective Longitudinal Mixed-Methods Study

Lisa A Niemann, Lauren R Violette, Andy Cornelius-Hudson, Maggie Murphy, Carl Capili, Mindy Dai, Anjuli Wagner, Sarah Frey, Shireesha Dhanireddy, Shaneil E Taylor, Karen W Hoover, Joanne D Stekler

JMIR Res Protoc 2026 (Jul 23); 15:e84625

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Manual Versus Instrumental Rotation of the Fetal Head in Malposition at Birth (ROTATE Study): Protocol for a Randomized Controlled Trial

Dawn Parris, Raffaele Napolitano, Jonathan Bishop, Annette Briley, Laura Butler, Versha Cheed, Anna L David, Zaina Habib, Pollyanna Hardy, Kim Hinshaw, Laura L Jones, Rachel Lillywhite, Eleanor Molloy, Jacqueline Nicholls, Stephen O'Brien, Rachel Plachcinski, Andrew Shennan, Nigel Simpson, Maureen Treadwell, Bassel Wattar, Andrew Weeks, The ROTATE Study Group, Dimitrios Siassakos

JMIR Res Protoc 2026 (Jul 22); 15:e72505

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Comparison of Traditional Chinese Manual Therapy (Tuina) and Extracorporeal Shock Wave Therapy in Patients With Nonspecific Neck Pain: Protocol for a Randomized Controlled Trial

Hongyu Li, Lili Zhao, Zhenning Zhao, Jing Mu, Huisheng Ma

JMIR Res Protoc 2026 (Jul 20); 15:e96555

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Clinical and Patient-Reported Outcomes of Laceback Ligature in Fixed Orthodontic Treatment: Protocol for a Randomized Controlled Trial

Loon Han Tan, Siti Hajjar Nasir, Joo Ming Cheong, Kumeran Mohan

JMIR Res Protoc 2026 (Jul 16); 15:e88793

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Optimizing Multicomponent Interventions to Improve Child Mental Health Following Reintegration From Institutions: Protocol for a Factorial Randomized Trial

Leyla Ismayilova, Narmin Guliyeva, Fuad Ismayilov, Emma Heidorn, Fred Ssewamala, Kerim Munir, Deborah Gorman-Smith, Emily Claypool, Parvin Muslumzada, Loren Beard, Donald Hedeker

JMIR Res Protoc 2026 (Jul 16); 15:e93033

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Clinical Study on the Prevention of High-Risk Pulmonary Nodule Progression With Yifei Sanjie Pill: Protocol for a Multicenter Randomized Controlled Trial

Bo An, Jietao Lin, Lizhu Lin, Xiangjun Qi, Yanlong Li, Minyi Guan, Zhiqiang Chen, Jingrui Wang, Lingling Sun

JMIR Res Protoc 2026 (Jul 15); 15:e78534

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Effects of Velocity-Based Resistance Training on Renal Function and Metabolic Health in Kidney Transplant Recipients: Protocol for a Pilot Randomized Controlled Trial

Jhonatan Camilo Peña Ibagon, Fermina Vasquez Osorio, Carlos Andrés Collazos Morales, Blanca Elpidia Tovar, William Felipe Martin1, Yordan Rene Pardo, Luis Andres Tellez

JMIR Res Protoc 2026 (Jul 10); 15:e94010

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Efficacy of an Ayurvedic Management Protocol on the Rate of Recurrence, Healing and Safety in Parikarthika (Fissure in Ano): Protocol for a Randomized Controlled Trial

Indu P P, Kalpana Kachare, Pratap Shankar K M, Binitha P, Lisha S, Bhagwan Sahai Sharma, Thugutla Maheswar, Narayanan Srikanth, Arunabh Tripathi, Rabinarayanan Acharya

JMIR Res Protoc 2026 (Jul 08); 15:e88548

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Efficacy, Safety, and Mechanism of the Qi-Lian-Xiao-Pi Prescription (WW-1) for Chronic Atrophic Gastritis After Helicobacter Pylori Eradication: Protocol for a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Wei Bai, Guodong Huang, Xianjun Rao, Hao Li, Tingting Zhou, Yang Yang, Wei Wei

JMIR Res Protoc 2026 (Jul 08); 15:e90965

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An Evidence-Based Cognitive Stimulation and Physical Activity Intervention to Delay Aging-Related Decline: Protocol for a Randomized Controlled Trial

Yook Chin Chia, Eden Ngah Den Low, Michael Jenkins, Yun Li Lee, Tin Tin Su, Rozainee Khairudin, Khazriyati Salehuddin, Santha Vaithilingam, Jactty Chew, Wei Ling Lim, Min Hooi Yong, Alexandre Schaefer

JMIR Res Protoc 2026 (Jul 08); 15:e88268

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Oral Health Promotion Among Students in Special Education Schools: Protocol for a Multicity Cluster Randomized Controlled Trial

Ruihang Zhang, Rong Lin, Wenyan Huang, Sujuan Zeng, Jiao Wang, Si Meng, Lin Xu

JMIR Res Protoc 2026 (Jul 03); 15:e93889

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A Stepped Care, Peer-Delivered Intervention to Improve Substance Use and HIV Medication Adherence in Primary Care in South Africa (Project Khanya): Protocol for a Hybrid Type 2 Effectiveness-Implementation Randomized Controlled Trial

Jessica F Magidson, Abigail C Hines, Sybil Hlombekazi Majokweni, Lwandile Tokwe, Bronwyn Myers, Stefani Du Toit, Kristen Regenauer, Lena S Andersen, Warren Burnhams, Catherine Orrell, Sean M Murphy, Goodman Sibeko, Noah Triplett, Esonasethu Ndwandwa, Neliswa Naledi Kotelo, Tianzhou Ma, Steven Safren, John Joska

JMIR Res Protoc 2026 (Jul 02); 15:e94153

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Home-Based, Virtually Supervised Combined Exercise Intervention in People With Parkinson Disease: Protocol for a Randomized Controlled Trial

Niyati Mehta, Miranda J Munoz, Isabel E Allen, Caroline M Tanner, Daniel M Corcos, Nijee S Luthra

JMIR Res Protoc 2026 (Jun 30); 15:e97507

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Evaluating Client-Centered Counseling Approaches to Improve Contraceptive Uptake at Family Planning Centers in Rawalpindi, Pakistan: Protocol for a Pilot Cluster-Randomized Trial

Farrah Pervaiz, Babar Tasneem Shaikh, Humaira Mahmood, Azka Naseem, Abdul Momin Rizwan Ahmad

JMIR Res Protoc 2026 (Jun 26); 15:e84267

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A Resiliency Intervention to Support Nurses Engaged in the Provision of HIV Care in KwaZulu-Natal, South Africa: Protocol for a Pilot Randomized Controlled Trial

Christina Psaros, Jennifer A Smit, Nzwakie Mosery, Lara N Traeger, Sanelisiwe Mngomezulu, Bongeka Qiya, Busi Maphumulo, Amelia M Stanton, Zoya-Maria R Aoun, C Andres Bedoya, Elyse R Park

JMIR Res Protoc 2026 (Jun 25); 15:e79777

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Early vs Late Initiation of Extracorporeal Membrane Oxygenation: Protocol for a Prospective, Randomized, Multicenter Study

Alice Bernard, Helene Haeberle, Valbona Mirakaj, Manola Zago, Michael Koeppen, Christina-Katharina Fodi, Peter Martus, Peter Rosenberger

JMIR Res Protoc 2026 (Jun 17); 15:e86652

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Evaluation of the TiaoShenZhiAi Regimen for Patients With Ovarian Cancer Experiencing a Psychoneurological Symptom Cluster: Protocol for a Multicenter, Double-Blind, Randomized Controlled Trial

Ze Liu, Jialiang Yao, Xinyi Lu, Yun Yang, Bin Luo, Yanhong Wang, Xi Cheng, Wei Jiang, Guowang Yang, Jing Xiao, Jiuda Zhao, Jianhui Tian

JMIR Res Protoc 2026 (Jun 12); 15:e88625

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