RCTs - Protocols/Proposals (funded, already peer-reviewed, eHealth)

Articles published in 2025-rcts-protocols-and-proposals-funded-already-peerreviewed-ehealth in this theme: 42 (scroll down to load remaining articles)

2025

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A Web-Based Contraception Decision Tool for Individuals With Health Conditions in US Outpatient Clinics: Protocol for a Mixed Methods Cluster Randomized Controlled Trial

Beatrice Palazzolo, James E Aikens, Ananda Sen, Timothy C Guetterman, Lorraine R Buis, Vanessa K Dalton, Brian J Zikmund-Fisher, Natabhona Mabachi, Minji Kang, Christine Dehlendorf, Murphy Van Sparrentak, Cory B Lutgen, Cynthia Wynn, Justine P Wu

JMIR Res Protoc 2025 (Dec 29); 14:e71101

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Exploring the Influence of a Novel App for Training and Evaluating Walking Aid Skills in Walking Aid Users: Protocol for a Pragmatic Single-Blind Randomized Controlled Trial

Félix Nindorera, Ranita H K Manocha, William C Miller, François Routhier, Krista L Best

JMIR Res Protoc 2025 (Dec 24); 14:e71060

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Meta Self-Efficacy Internet Intervention to Support Occupational Health in Young Employees: Protocol for Co-Creation and a Randomized Controlled Trial

Jan Maciejewski, Roman Cieslak, Per Carlbring, Ewelina Smoktunowicz

JMIR Res Protoc 2025 (Dec 23); 14:e85082

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Effects of a Walking-Based Physical Activity Intervention on Health Indicators in University Students: Protocol for a Randomized Controlled Trial

Andrés Godoy-Cumillaf, Paola Fuentes-Merino, Frano Giakoni-Ramírez, Catalina Muñoz-Strale, Josivaldo de Souza-Lima, Daniel Duclos-Bastías, Maribel Parra-Saldías, José Bruneau-Chávez, Eugenio Merellano-Navarro

JMIR Res Protoc 2025 (Dec 10); 14:e83983

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The Effect of Motor Imagery Ability on Function and Proprioception in Myoelectric Prosthesis Users: Protocol for a Cross-Sectional Study

Ayşe Yazgan, Zeliha Candan Algun, Elif Aleyna Yazgan

JMIR Res Protoc 2025 (Dec 08); 14:e83787

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Modifying Tobacco and Cannabis Waste Perceptions and Behavior Among Young Adults: Protocol for a Randomized Controlled Trial

Kim Pulvers, AB Nordskog, Hadley Shearer, Cheyenne Smith, Susan L Stewart, Thomas E Novotny, Elisa K Tong

JMIR Res Protoc 2025 (Dec 04); 14:e79525

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Establishing a Pharmacy-Based Pre-Exposure Prophylaxis Program for Young Women Who Sell Sex: Protocol for a Randomized Controlled Trial

Oppah Kuguyo, Helena Archer, Lance Azizi, Constancia Watadzaushe, Sharon Munhenzva, Kudzai Chidhanguro, Albert Takaruza, Sithembile Musemburi, Laura Packel, Jenny Liu, Primrose Matambanadzo, Frances M Cowan, Sandra McCoy, Euphemia L Sibanda

JMIR Res Protoc 2025 (Dec 03); 14:e74141

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Scaling European Citizen Driven Transferable and Transformative Digital Health: Protocol for an Effectiveness-Implementation Hybrid Trial of a Digital Health Platform to Support Multimorbidity Self-Management

Julie Doyle, Séamus Harvey, Sara Polak, Myriam Sillevis Smitt, Jane Murphy, Áine Teahan, Jessica Ferreira Morais, Suzanne Smith, Orla Moran, Gordon Boyle, An Jacobs, Sarah Anne Tighe, John Dinsmore

JMIR Res Protoc 2025 (Nov 25); 14:e74989

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Increasing Physical Activity via Provider Support and Engagement Using a Digital Health Platform in Adults With Multiple Sclerosis: Protocol for a Randomized Controlled Trial

Dawn M Ehde, Sarah B Simmons, Kevin N Alschuler, Tracy E Herring, Andrew T Humbert, Susan R Robles, Otari Ioseliani, Karla Landis, Laurie B Kavanagh, Cindy Y Lin

JMIR Res Protoc 2025 (Nov 21); 14:e72213

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Effects of Communicating Genetic Risk of Type 2 Diabetes and Wearable Technologies on Behavioral Outcomes in East Asians: Statistical Analysis Protocol for a Randomized Controlled Trial

Harrison Hin Sheung Ho, Ziyuan Chen, Job Godino, Michael Multhaup, Derwin King Chung Chan, Shiu Lun Au Yeung, Shan Luo, Brian Hon Yin Chung, Simon Griffin, Youngwon Kim

JMIR Res Protoc 2025 (Nov 05); 14:e65012

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A Smartphone App (PRIMI) to Promote Healthy Diet, Physical Activity, and Health Literacy After Childbirth Among Migrant Women: Protocol for a Randomized Controlled Trial

Anna Seiterö, Maryam Shirvanifar, Marie Jubran Leksell, Maria Rydfjord, Baydaa Al-saedi, Aisha Salah Ahmed, Tayebeh Gharakhani Bahar, Daniel Berglind, Hanna Henriksson, Viktor H Ahlqvist, Josefin Wångdahl, Ulrika Müssener, Pontus Henriksson

JMIR Res Protoc 2025 (Oct 17); 14:e79277

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Effectiveness of the Essential Coaching Postpartum Digital Health Solution on Parenting Self-Efficacy, Mental Health, Well-Being, and Parenting Outcomes: Protocol for a Randomized Controlled Trial

Justine Dol, Christine T Chambers, Jennifer A Parker, Melissa Brooks, Cindy-Lee Dennis, Daniel Seguin, Jennifer M Goldberg, Brad Hughes, Teresa Reese, Greg Richard, Kate Calnan

JMIR Res Protoc 2025 (Oct 17); 14:e78209

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Comparison of Ketorolac at 3 Doses in Children With Acute Pain: Protocol for A Randomized Controlled Trial

Mohamed Eltorki, Redjana Carciumaru, Samina Ali, Anne Holbrook, Michael Livingston, Samira Samiee-Zafarghandy, Karen Beattie, Lehana Thabane, Lucia Giglia

JMIR Res Protoc 2025 (Oct 09); 14:e76554

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Innovative Web-Based Future Planning and Well-Being for Caregivers of Individuals With Intellectual and Developmental Disabilities: Protocol of a Pragmatic Randomized Controlled Trial

Caren Steinway, Charmaine Wright, Silvia Kwak, Olivia Teng, Abigail Seide, John Berens, Jason Woodward, Ilka Riddle, Thomas Davis, Adam Greenberg, Dava Szalda, Justine Shults, Jane Cerise, Sophia Jan

JMIR Res Protoc 2025 (Oct 01); 14:e77184

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A Technology-Enhanced Medical Nutrition Therapy and Diabetes Self-Management Education for Adults With Disability and Type 2 Diabetes: Protocol for a Pilot and Feasibility Randomized Controlled Trial

Anita Aboagye, Jessica Peckham, Kristine Ria Hearld, Shireen Abdullah, Mohanraj Thirumalai

JMIR Res Protoc 2025 (Sep 26); 14:e71495

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Codeveloping a Novel Intervention to Promote the Well-Being of Family Caregivers of Individuals With Spinal Cord Injury: Protocol for a Feasibility Randomized Control Trial

Somayyeh Mohammadi, Beth Erlander, Heather Cathcart, Julie M Robillard, Sophia Sauvageau, David G T Whitehurst, Elena Pauly, Brooke Pagé, William C Miller

JMIR Res Protoc 2025 (Sep 25); 14:e67709

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Aiding Chronic Obstructive Pulmonary Disease and Congestive Heart Failure Ultrasound-Guided Management Through Enhanced Point-of-Care Ultrasound (ACCUMEN-POCUS): Protocol for a Randomized Controlled Trial

Michelle Nora Grinman, Peter Nakhla, Steve Reid, Dennis Moon, Negar Dehghan Noudeh, Oladoyin Olaosebikan, Amanda Chung Yan Ip, Salomé Saunders, Ryan Kozicky, John Conly, Andrew Wallace Kirkpatrick, Jeff Round, Irene Wai Yan Ma, Suean Pascoe, Ghazwan Altabbaa

JMIR Res Protoc 2025 (Sep 23); 14:e76186

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Home-Based Exercise to Improve Functional Outcomes in Veterans With a Recently Healed Diabetic Foot Ulcer: Protocol for a Pilot Randomized Controlled Trial

Gwen L Robinson, Jake Drumheller, Alison D Lydecker, Bailey Rammling, Elizabeth A Dennis, Odessa Addison, Steven J Prior, Brock A Beamer, John D Sorkin, H David Gottlieb, Kiana Trent, Mary-Claire Roghmann

JMIR Res Protoc 2025 (Sep 23); 14:e71237

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Examining the Effect of Virtual Reality–Based Fast-Food Marketing on Eating-Related Outcomes in Young Adults: Protocol for a Randomized Controlled Trial

Omni Cassidy, Emma Boyland, Susan Persky, Andrea B Troxel, Brian Elbel

JMIR Res Protoc 2025 (Sep 22); 14:e69096

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Effectiveness of Synchronous Telerehabilitation Versus Face-to-Face Physical Therapy in Older Adults Who Are Frail: Protocol for a Randomized Controlled Trial

Igor Cigarroa, Daniel Reyes-Molina, Felipe Vargas-Rios, Gustavo López-Alarcón, Sergio Jara-Aceituno, Cristobal Riquelme-Hernández, Rafael Zapata-Lamana, María Antonia Parra-Rizo

JMIR Res Protoc 2025 (Sep 16); 14:e72318

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