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Published on in Vol 15 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/96292, first published .
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The Preliminary Efficacy and Feasibility of SMILE Serious Game for Adolescents and Young Adults: Protocol for Cluster Randomized Multisite Adaptive Trial Design

The Preliminary Efficacy and Feasibility of SMILE Serious Game for Adolescents and Young Adults: Protocol for Cluster Randomized Multisite Adaptive Trial Design

Ewelina Smoktunowicz   1 , PhD ;   Jan Maciejewski   1 , MSc ;   Magdalena Lesnierowska   1 , PhD ;   Magdalena Pietrzak   2 , MSc ;   Franziska Großwendt   3 , MSc ;   Gwendolyn Mayer   3 , PhD ;   Jobst-Hendrik Schultz   3 , PhD ;   Nelli Tschobur   3 , MSc ;   Mel McKendrick   4 , PhD ;   Helen Stocks   4 , MSc ;   Francesca Floris   5 , MSc ;   Dina Guglielmi   5 , PhD ;   Zouhair Haddi   6 , PhD ;   Carlo Mazzola   6 , PhD ;   Izidor Mlakar   7 , PhD ;   Urška Smrke   7 , PhD ;   Laura Fernández García   8 , MSc ;   Esther Parra Vidales   8 , MSc ;   Elisa Sáez Muñoz   8 , MSc ;   Sebastian Bruchhaus   9 , MSc ;   Matthias Hemmje   9 , PhD ;   Dominic Heutelbeck   9 , PhD ;   Dah Diarra   10 , MSc ;   Habib Nasser   10 , PhD ;   Alex Butean   11, 12 , PhD ;   Marco Polak   13 ;   Panagiota Mourettou   14 , MRes ;   Angelos Parmatzias   14 , MBA ;   Ula Kolinska   15 , MSc ;   Matthias Schwannauer   15 , PhD

1 StresLab Research Center, Institute of Psychology, SWPS University, Warsaw, Poland

2 Institute of Psychology, SWPS University, Warsaw, Poland

3 Department of General Internal and Psychosomatic Medicine, University Hospital Heidelberg, Heidelberg, Baden-Wurttemberg, Germany

4 School of Social Sciences, Heriot-Watt University, Edinburgh, Scotland, United Kingdom

5 Department of Education Studies, University of Bologna, Bologna, Italy

6 Digital Health Department, NVISION Systems and Technologies, Barcelona, Spain

7 Faculty of Electrical Engineering and Computer Science, University of Maribor, Maribor, Slovenia

8 Fundación INTRAS, Valladolid, Castille and León, Spain

9 Research Institute for Telecommunication Cooperation, Dortmund, North Rhine-Westphalia, Germany

10 RDIUP, Les Mureaux, France

11 WIZ Development and Services SRL, Sibiu, Romania

12 Lucian Blaga University of Sibiu, Sibiu, Romania

13 DigitalTwin Technology GmbH, Cologne, Germany

14 Citizens in Power, Nicosia, Cyprus

15 School of Health in Social Science, University of Edinburgh, Edinburgh, Scotland, United Kingdom

Corresponding Author:

  • Ewelina Smoktunowicz, PhD
  • StresLab Research Center, Institute of Psychology, SWPS University
  • Chodakowska 19/31
  • Warsaw 03-815
  • Poland
  • Phone: 48 225179921
  • Email: esmoktunowicz@swps.edu.pl