Study of High-Velocity Nasal Insufflation vs Noninvasive Positive Pressure Ventilation for Emergency Type 2 Respiratory Failure: Protocol for a Noninferiority Randomized Controlled Trial

Published on 14.Aug.2026 in Vol 15 (2026)

This is a member publication of Bodleian Libraries (Jisc)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/93391, first published 12.Feb.2026.

; Darius Shaw Teng Pan^{3, 4, 5}

; Alexander Jet Yue Ng^{1, 2, 3}

; Crystal Harn Wei Soh^{1, 2, 3}

; Win Sen Kuan^{1, 2, 3}

Mui Teng Chua ^{1, 2, 3} , MBBS, MMed, MPH ; Darius Shaw Teng Pan ^{3, 4, 5} , MBBS (Hons), MMed ; Alexander Jet Yue Ng ^{1, 2, 3} , MBBS, MMed ; Crystal Harn Wei Soh ^{1, 2, 3} , MBBS, MMed ; Win Sen Kuan ^{1, 2, 3} , MBBS, MRCSEd (A&E), MCI

¹ Emergency Medicine Department, National University Hospital, Singapore, Singapore

² Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

³ Urgent Care Centre, Alexandra Hospital, Singapore, Singapore

⁴ Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, England, United Kingdom

⁵ Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

Corresponding Author: