Multidisciplinary Treatment With Hepatic Arterial Infusion Chemotherapy, Radiotherapy, and Immunotherapy for Advanced Hepatocellular Carcinoma With Major Vascular Invasion: Prospective Registry Protocol

Yoshiko Doi   ^{1 *} , MD, PhD ;   Hiroshi Aikata   ^{2 *} , MD, PhD ;   Yumi Kosaka   ² , MD, PhD ;   Takashi Nakahara   ² , MD, PhD ;   Michiyo Kodama   ³ , MD, PhD ;   Masashi Hieda   ⁴ , MD, PhD ;   Masakazu Hashimoto   ⁵ , MD, PhD ;   Hideki Nakahara   ⁵ , MD, PhD ;   Ippei Takahashi   ⁶ , MD, PhD ;   Hideaki Kakizawa   ⁷ , MD, PhD ;   Nami Mori   ⁸ , MD, PhD ;   Keiji Tsuji   ⁸ , MD, PhD ;   Nobuki Imano   ⁹ , MD, PhD ;   Yuji Murakami   ⁹ , MD, PhD ;   Saki Sueda   ¹⁰ , MD ;   Tomokazu Kawaoka   ¹⁰ , MD, PhD ;   Masataka Tsuge   ¹¹ , MD, PhD ;   Shiro Oka   ¹⁰ , MD, PhD

¹ Department of Radiation Oncology, Hiroshima Prefectural Hospital, Hiroshima, Japan

² Department of Gastroenterology and Hepatology, Hiroshima Prefectural Hospital, Hiroshima, Japan

³ Department of Medical Oncology, Hiroshima Prefectural Hospital, Hiroshima, Japan

⁴ Department of Diagnostic Radiology, Hiroshima Prefectural Hospital, Hiroshima, Japan

⁵ Department of Gastroenterological Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan

⁶ Department of Radiation Oncology, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan

⁷ Department of Diagnostic Radiology, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan

⁸ Department of Gastroenterology and Hepatology, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan

⁹ Department of Radiation Oncology, Hiroshima University Hospital, Hiroshima, Japan

¹⁰ Department of Gastroenterology, Hiroshima University Hospital, Hiroshima, Japan

¹¹ Liver Center, Hiroshima University Hospital, Hiroshima, Japan

*these authors contributed equally