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Published on in Vol 15 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/82619, first published .
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A Large, Diverse, Urban Cardiovascular Health e-Cohort in Childhood and Adolescence: Protocol for the Young Hearts Study

A Large, Diverse, Urban Cardiovascular Health e-Cohort in Childhood and Adolescence: Protocol for the Young Hearts Study

Lucia C Petito   1 , PhD ;   Rachel Zmora   1 , PhD ;   Aashima Chopra   1 , MPH ;   Yaojie Wang   1 , MS ;   Darci Phillips   1 , MPH ;   Ileah Rios   1 , MPH ;   Mark Pletcher   2 , MD, MPH ;   Rupali Gandhi   3 , MD ;   Huma Khan   4 , MD ;   Cheryl Lefaiver   5 , RN, PhD ;   Amanda Luff   5 , MPH, PhD ;   Rashmi Narayan   6 , MD ;   Sarah De Ferranti   7, 8 , MD, MPH ;   Holly C Gooding   9 , MD, MSc ;   Stephen Daniels   10 , MD, PhD ;   Brad Appelhans   11 , PhD ;   Karen Lui   11 , MD ;   Francis J Alenghat   12 , MD, PhD ;   Rachel Caskey   12 , MD, MAPP ;   Matthew M Davis   13 , MD ;   Marc B Rosenman   14, 15, 16 , MD ;   Darwin R Labarthe   1 , MD, MPH, PhD ;   Donald M Lloyd-Jones   1, 15, 17 , MD, ScM ;   Amanda M Perak   1, 14, 18, 19 , MD, MS ;   Norrina B Allen   1 , PhD

1 Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States

2 Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, Francisco, CA, United States

3 Advocate Children's Medical Group Pediatric Cardiology, Advocate Health Care, Oak Lawn, IL, United States

4 Advocate Children's Medical Group Adolescent Medicine, Advocate Health Care, Evergreen Park, IL, United States

5 Advocate Aurora Research Institute, Advocate Health, Milwaukee, WI, United States

6 AllianceChicago, Chicago, IL, United States

7 Department of Cardiology, Boston Children’s Hospital, Boston, MA, United States

8 Department of Pediatrics, Harvard Medical School, Boston, MA, United States

9 Department of Pediatrics, Emory University School of Medicine and Children’s Healthcare of Atlanta, Atlanta, GA, United States

10 Department of Pediatrics, University of Colorado Anschutz Medical Campus And Children’s Hospital Colorado, Aurora, CO, United States

11 Department of Family and Preventive Medicine, Rush University System for Health, Chicago, IL, United States

12 Department of Medicine, University of Illinois Chicago, Chicago, IL, United States

13 Department of Medical Social Science, Nemours Children's Health, Jacksonville, FL, United States

14 Stanley Manne Children’s Research Institute, Chicago, IL, United States

15 Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States

16 Mary Ann and J. Milburn Smith Child Health Outcomes, Research, and Evaluation Center, Ann and Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, United States

17 Boston University Chobanian & Avedisian School of Medicine, Boston, MA, United States

18 Department of Pediatrics, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States

19 Ann and Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, United States

Corresponding Author:

  • Norrina B Allen, PhD
  • Department of Preventive Medicine
  • Northwestern University Feinberg School of Medicine
  • Ste 1400, 680 N Lake Shore Dr
  • Chicago, IL 60611
  • United States
  • Phone: 1 3129087914
  • Email: norrina-allen@northwestern.edu