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Published on in Vol 15 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/81858, first published .
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Structured Online Support to Inform and Assist Antidepressant Deprescribing in Primary Care (WiserAD Tool): Protocol for a Pragmatic Randomized Controlled Trial

Structured Online Support to Inform and Assist Antidepressant Deprescribing in Primary Care (WiserAD Tool): Protocol for a Pragmatic Randomized Controlled Trial

Catherine Kaylor-Hughes   1 , DPhil ;   Amy Coe   1 , PhD ;   Patty Chondros   1 , PhD ;   Konstancja Densley   1 , MA, MSc, PGDip ;   Susan Fletcher   1 , PhD ;   Mary-Lou Chatterton   2 , PhD ;   Daniel Hoyer   3, 4, 5 , PhD ;   Timothy Chen   6 , PhD ;   Chee Ng   7 , MMed, MD ;   Derelie Mangin   8, 9 , DPH, PhD ;   Tony Kendrick   10 , MBBS, MD ;   Zoe Allnutt   1 , Grad Cert, BNAD ;   Jane Gunn AO   1 , MBBS, PhD

1 Department of General Practice and Primary Care, University of Melbourne, Melbourne, Australia

2 School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

3 Department of Biochemistry & Pharmacology, University of Melbourne, Melbourne, Australia

4 Florey Institute of Neuroscience and Mental Health, Victoria, Australia

5 Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA, United States

6 Sydney Pharmacy School, University of Sydney, Sydney, Australia

7 Department of Psychiatry, University of Melbourne, Melbourne, Australia

8 Department of Family Medicine, McMaster University, Hamilton, ON, Canada

9 Department of General Practice, University of Otago, Christchurch, New Zealand

10 School of Primary Care, Population Sciences and Medical Education, University of Southampton, Southampton, United Kingdom

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