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Published on in Vol 15 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/103430, first published .
Young Asian man in blue sweater using smartphone outdoors

Smartphone-Delivered Cognitive Behavioral Digital Therapeutic for Children and Adolescents With Major Depressive Disorder: Protocol for a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Smartphone-Delivered Cognitive Behavioral Digital Therapeutic for Children and Adolescents With Major Depressive Disorder: Protocol for a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Xue Li   1 , MD ;   Qingjiu Cao   1 , MD ;   Li Sun   1 , MD, PhD ;   Ying Qian   1 , MD ;   Minglong Gao   2 , MMed ;   Lan Wang   2 , MD ;   Wenting Lu   2 , MD ;   Xianglan Wang   3 , MD ;   Hong Wang   3 , MMed ;   Xuejiao Hou   3 , MMed ;   Jing Liu   1 , MMed

1 Beijing Key Laboratory for Big Data Innovative Application of Child and Adolescent Mental Disorders, NHC Key Laboratory of Mental Health, National Clinical Research Center for Mental Disorders, Peking University Sixth Hospital (Peking University Institute of Mental Health), Peking University, Beijing, Beijing, China

2 The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China

3 Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong, China

Corresponding Author:

  • Jing Liu, MMed
  • Beijing Key Laboratory for Big Data Innovative Application of Child and Adolescent Mental Disorders, NHC Key Laboratory of Mental Health
  • National Clinical Research Center for Mental Disorders
  • Peking University Sixth Hospital (Peking University Institute of Mental Health), Peking University
  • 51 Huayuan N Rd
  • Haidian District
  • Beijing, Beijing 100083
  • China
  • Phone: 86 01082801939
  • Email: ljyuch@bjmu.edu.cn