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This paper is in the following e-collection/theme issue:

RCTs - Protocols/Proposals (eHealth) (1328) Mobile Health (mhealth) (5080) Depression and Mood Disorders; Suicide Prevention (2414) Engagement with and Adherence to Digital Health Interventions, Law of Attrition (793) Prescribable Digital Interventions (Digital Therapeutics) (77) AI-Powered Therapy Bots and Virtual Companions in Digital Mental Health (82)

Published on in Vol 14 (2025)

This is a member publication of University of Washington

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/81293, first published .
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Effectiveness, Engagement, and Safety of a Digital Therapeutic (CT-155/BI 3972080) for Treating Negative Symptoms in People With Schizophrenia: Protocol for the Phase 3 CONVOKE Randomized Controlled Trial

Effectiveness, Engagement, and Safety of a Digital Therapeutic (CT-155/BI 3972080) for Treating Negative Symptoms in People With Schizophrenia: Protocol for the Phase 3 CONVOKE Randomized Controlled Trial

Authors of this article:

Shaheen E Lakhan1 Author Orcid Image ;   Cornelia Dorner-Ciossek2 Author Orcid Image ;   Olya Besedina1 Author Orcid Image ;   Faith Dickerson3 Author Orcid Image ;   Claudia Hastedt2 Author Orcid Image ;   Ridwana Isla4 Author Orcid Image ;   René S Kahn5 Author Orcid Image ;   Jean-Pierre Lindenmayer6 Author Orcid Image ;   Ruchi Mehta1 Author Orcid Image ;   Cassandra Snipes1 Author Orcid Image ;   Austin Speier1 Author Orcid Image ;   Wenbo Tang4 Author Orcid Image ;   Bailey Willis1 Author Orcid Image ;   Jamie Winderbaum Fernandez7 Author Orcid Image ;   Christoph von der Goltz2 Author Orcid Image ;   Abhishek Pratap4 Author Orcid Image
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Journals

  1. Gandhi A, Firmin R, Luther L, Wahid N, Parcher B, Brown J, Machniewska G, Hare B, Perocco S, Strauss G, Dorner-Ciossek C, Pratap A. Patient Perspectives on a Digital Therapeutic for Schizophrenia: A Qualitative Evaluation of an App for Negative Symptoms. Schizophrenia Bulletin Open 2025;6(1) View
  2. 张 超. Research Progress on Digital Biomarkers and Digital Therapeutics for Schizophrenia. Advances in Psychology 2026;16(01):226 View
  3. Palaniyappan L, Baillet S, Bambini V, Barou-Laforie E, Bosia M, Delgaram-Nejad O, Ganesh H, Garani R, Harrison N, Hodgins V, Joober R, Kircher T, Kuperberg G, Murthy C, Rossell S, Singh K, Sommer I, Tang S, Titone D, Voppel A, Watson T, Zeljkovic I. Increasing participation of people with thought disorder in clinical research. European Psychiatry 2026;69(1) View