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Published on in Vol 14 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/77681, first published .
Doctors review MRI scan of brain in medical imaging room with patient in scanner.

The White Matter Hyperintensity Shape and Brain Clearance (WHIMAS) Study for Identification of Novel 7T Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease: Protocol for a Cross-Sectional Study

The White Matter Hyperintensity Shape and Brain Clearance (WHIMAS) Study for Identification of Novel 7T Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease: Protocol for a Cross-Sectional Study

Jasmin Annica Kuhn-Keller   1, 2 , PhD ;   Ingmar Eiling   1, 2 , MSc ;   Lydiane Hirschler   1, 2 , PhD ;   Lena Václavů   1, 2 , PhD ;   Marie-Noëlle Witjes-Ané   3, 4 , PhD ;   Marjolein Wijngaarden   3, 5 , MD, PhD ;   Martijn Nagtegaal   1, 2 , PhD ;   Ece Ercan   1, 2 , PhD ;   Nathaly Rius Ottenheim   4 , MD, PhD ;   Marjan van der Elst   3, 5 , RN ;   Evelien Sohl   6 , MD ;   Mark A van Buchem   2 , MD, PhD ;   Simon Mooijaart   3, 5 , MD, PhD ;   Matthias JP van Osch   1, 2 , PhD ;   Jeroen de Bresser   2 , MD, PhD

1 CJ Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, South Holland, The Netherlands

2 Department of Radiology, Leiden University Medical Center, Leiden, South Holland, The Netherlands

3 Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, South Holland, The Netherlands

4 Department of Psychiatry, Leiden University Medical Center, Leiden, South Holland, The Netherlands

5 Center for Medicine for Older People, Leiden University Medical Center, Leiden, South Holland, The Netherlands

6 Department of Geriatrics, Alrijne Hospital Leiden, Leiden, South Holland, The Netherlands

Corresponding Author:

  • Jeroen de Bresser, MD, PhD
  • Department of Radiology
  • Leiden University Medical Center
  • Albinusdreef 2
  • Leiden, South Holland 2333 ZA
  • The Netherlands
  • Phone: 31 715264376
  • Email: J.H.J.M.de_Bresser@lumc.nl