Optimization of Preemptive Therapy for Cytomegalovirus Infections With Valganciclovir Based on Therapeutic Drug Monitoring: Protocol for a Phase II, Single-Center, Single-Arm Trial

Naoki Tamura   ^{1, 2} , BS ;   Kotaro Itohara   ¹ , PhD ;   Yo Ueda   ³ , MD, PhD ;   Yumi Kitahiro   ¹ , PhD ;   Kazuhiro Yamamoto   ^{1, 4} , PhD ;   Tomohiro Omura   ¹ , PhD ;   Toshiyasu Sakane   ² , PhD ;   Jun Saegusa   ³ , MD, PhD ;   Ikuko Yano   ¹ , PhD

¹ Department of Pharmacy, Kobe University Hospital, Kobe, Japan

² Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Kobe, Japan

³ Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan

⁴ Department of Integrated Clinical and Basic Pharmaceutical Sciences, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan