An Interdisciplinary Ecosystem for the Prevention of Cardiotoxicity in Older Patients With Breast Cancer: Protocol for a Prospective and Multicentric Study

Gaia Giulia Angela Sacco   ^{1 *} , MSc ;   Ketti Mazzocco   ^{1, 2 *} , PhD, PsyD ;   Anastasia Constantinidou   ³ , MD, PhD ;   Andri Papakonstantinou   ⁴ , MD, PhD ;   Davide Mauri   ⁵ , MD ;   Grigorios Kalliatakis   ⁶ , PhD ;   Manolis Tsiknakis   ⁷ , PhD ;   Domen Ribnikar   ⁸ , MD ;   Dorothea Tsekoura   ⁹ , MD, PhD ;   Valantis Aidarinis   ⁹ , MSc ;   Kalliopi Keramida   ¹⁰ , MD, PhD ;   Panagiotis Oikonomopoulos   ¹⁰ , PhD ;   Athos Antoniades   ¹¹ , PhD ;   Cameron Brown   ¹¹ , PhD ;   Federica Rizzi   ¹² , PhD ;   Anca Bucur   ¹³ , PhD ;   Elsa Pacella   ¹⁴ , MSc ;   Georgia Karanasiou   ¹⁵ , PMP ;   Daniela Cardinale   ¹ , MD, PhD ;   Carlo Cipolla   ¹ , MD ;   Elisabetta Munzone   ¹ , MD ;   Dimitrios Fotiadis   ¹⁵ , PhD ;   Giuseppe Curigliano   ^{1, 2} , MD, PhD ;   Gabriella Pravettoni   ^{1, 2} , PhD, PsyD

¹ European Institute of Oncology, IRCCS, Milan, Italy

² Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy

³ Medical Oncology Department, Bank of Cyprus Oncology Centre, Nicosia, Cyprus

⁴ Oncology-Pathology Dept., Karolinska Institutet - Cancer Center Karolinska (CCK), Solna, Sweden

⁵ Medical Oncology Department, General Hospital of Lamia, Lamia, Greece

⁶ Computation, Computational BioMedicine Laboratory (CBML), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Greece

⁷ Department of Electrical & Computer Engineering, Hellenic Mediterranean University (HMU), Chania, Greece

⁸ Medical Oncology Department, Institute of Oncology Ljubljana, Ljubljana, Slovenia

⁹ 2nd Department of Surgery, Aretaieio University Hospital, National and Kapodistrian University of Athens, Athens, Greece

¹⁰ 2nd Department of Cardiology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece

¹¹ Stremble Ventures LTD, Limassol, Cyprus

¹² IMS - Istituto di Management Sanitario, Bresso, Italy

¹³ Philips Research Europe, Eindhoven, The Netherlands

¹⁴ ESC, European Society of Cardiology, Sophia Antipolis, France

¹⁵ Department of Materials Science and Engineering, UOI - University of Ioannina, Ioannina, Greece

*these authors contributed equally