Metabolic Syndrome Parameters, Determinants, and Biomarkers in Adult Survivors of Childhood Cancer: Protocol for the Dutch Childhood Cancer Survivor Study on Metabolic Syndrome (Dutch LATER METS)

Vincent Pluimakers   ¹ , MD ;   Marta Fiocco   ^{1, 2, 3} , PhD ;   Jenneke van Atteveld   ¹ , MD ;   Monique Hobbelink   ⁴ , MD ;   Dorine Bresters   ¹ , MD, PhD ;   Eline Van Dulmen-den Broeder   ^{1, 5} , PhD ;   Margriet Van der Heiden-van der Loo   ⁶ , PhD ;   Geert O Janssens   ^{1, 4} , MD, PhD ;   Leontien Kremer   ^{1, 5} , MD ;   Jacqueline Loonen   ⁷ , MD, PhD ;   Marloes Louwerens   ² , MD ;   Helena Van der Pal   ¹ , MD, PhD ;   Cécile Ronckers   ^{1, 5, 8} , PhD ;   Hanneke Van Santen   ^{1, 9} , MD, PhD ;   Birgitta Versluys   ^{1, 9} , MD, PhD ;   Andrica De Vries   ^{1, 10} , MD, PhD ;   Marry Van den Heuvel-Eibrink   ¹ , MD ;   Sebastian Neggers   ^{1, 11} , MD, PhD

¹ Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands

² Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands

³ Mathematical Institute, Leiden University, Leiden, The Netherlands

⁴ Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

⁵ Department of Pediatric Oncology, Emma Children’s Hospital/Amsterdam University Medical Center, Amsterdam, The Netherlands

⁶ Dutch Childhood Oncology Group, Utrecht, The Netherlands

⁷ Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands

⁸ Institute of Biostatistics and Registry Research, Brandenburg Medical School Theodor Fontane, Neuruppin, Germany

⁹ Department of Pediatric Oncology and Hematology, Wilhelmina Children’s Hospital/University Medical Center Utrecht, Utrecht, The Netherlands

¹⁰ Department of Pediatric Oncology/Hematology, Sophia Children’s Hospital/Erasmus Medical Center, Rotterdam, The Netherlands

¹¹ Department of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands