This paper is in the following e-collection/theme issue:

Methods and Feasibility Studies (405) Validity, Reliability, and Bias (105)

Published on in Vol 9, No 5 (2020): May

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/17603, first published .
An Ecologically Valid, Longitudinal, and Unbiased Assessment of Treatment Efficacy in Alzheimer Disease (the EVALUATE-AD Trial): Proof-of-Concept Study

An Ecologically Valid, Longitudinal, and Unbiased Assessment of Treatment Efficacy in Alzheimer Disease (the EVALUATE-AD Trial): Proof-of-Concept Study

An Ecologically Valid, Longitudinal, and Unbiased Assessment of Treatment Efficacy in Alzheimer Disease (the EVALUATE-AD Trial): Proof-of-Concept Study

Authors of this article:

Neil William Douglas Thomas1, 2, 3, 4 Author Orcid Image ;   Zachary Beattie3 Author Orcid Image ;   Jennifer Marcoe3 Author Orcid Image ;   Kirsten Wright3 Author Orcid Image ;   Nicole Sharma3 Author Orcid Image ;   Nora Mattek3 Author Orcid Image ;   Hiroko Dodge3, 5 Author Orcid Image ;   Katherine Wild3 Author Orcid Image ;   Jeffrey Kaye3, 4 Author Orcid Image
Article Authors Cited by (21) Tweetations (3) Metrics

Journals

  1. Miller L, Steele J, Wu C, Kaye J, Dodge H, Gonzales M, Lyons K. Depressive symptoms in older adult couples: Associations with dyadic physical health, social engagement, and close friends. Frontiers in Psychiatry 2022;13 View
  2. Miller L, Solomon D, Whitlatch C, Hiatt S, Wu C, Reynolds C, Au-Yeung W, Kaye J, Steele J, Pak R. The Remote Assessment and Dynamic Response Program: Development of an In-Home Dementia-Related Care Needs Assessment to Improve Well-Being. Innovation in Aging 2022;6(2) View
  3. Chen M, Leow A, Ross M, DeLuca J, Chiaravalloti N, Costa S, Genova H, Weber E, Hussain F, Demos A. Associations between smartphone keystroke dynamics and cognition in MS. DIGITAL HEALTH 2022;8:205520762211432 View
  4. Gilson A, Gassman M, Dodds D, Lombardo R, Ford II J, Potteiger M. Refining a Digital Therapeutic Platform for Home Care Agencies in Dementia Care to Elicit Stakeholder Feedback: Focus Group Study With Stakeholders. JMIR Aging 2022;5(1):e32516 View
  5. Thomas N, Beattie Z, Riley T, Hofer S, Kaye J. Home-Based Assessment of Cognition and Health Measures: The Collaborative Aging Research Using Technology (CART) Initiative and International Collaborations. IEEE Instrumentation & Measurement Magazine 2021;24(6):68 View
  6. Beattie Z, Miller L, Almirola C, Au-Yeung W, Bernard H, Cosgrove K, Dodge H, Gamboa C, Golonka O, Gothard S, Harbison S, Irish S, Kornfeld J, Lee J, Marcoe J, Mattek N, Quinn C, Reynolds C, Riley T, Rodrigues N, Sharma N, Siqueland M, Thomas N, Truty T, Wall R, Wild K, Wu C, Karlawish J, Silverberg N, Barnes L, Czaja S, Silbert L, Kaye J. The Collaborative Aging Research Using Technology Initiative: An Open, Sharable, Technology-Agnostic Platform for the Research Community. Digital Biomarkers 2020;4(Suppl. 1):100 View
  7. Masi G, Amprimo G, Priano L, Ferraris C. New Perspectives in Nonintrusive Sleep Monitoring for Neurodegenerative Diseases—A Narrative Review. Electronics 2023;12(5):1098 View
  8. Kim Y, Shin B, Kim K. Digital Biomarkers for Alzheimer’s Disease. Journal of the Korean Neurological Association 2023;41(4):268 View
  9. Machado S, Tavares J, Barbosa J. Technologies for monitoring patients with Alzheimer’s disease: A systematic mapping study and taxonomy. Journal of Ambient Intelligence and Smart Environments 2024;16(1):3 View
  10. Kessler D, Franz M, Levy M, Vrckovnik A, Thomas N, Finlayson M, Knoefel F. Supporting compassionate use of technology to support functioning in daily activities among people with cognitive decline – a scoping review. Disability and Rehabilitation: Assistive Technology 2024;19(8):2834 View
  11. Scaramozza M, Ruet A, Chiesa P, Ahamada L, Bartholomé E, Carment L, Charre-Morin J, Cosne G, Diouf L, Guo C, Juraver A, Kanzler C, Karatsidis A, Mazzà C, Penalver-Andres J, Ruiz M, Saubusse A, Simoneau G, Scotland A, Sun Z, Tang M, van Beek J, Zajac L, Belachew S, Brochet B, Campbell N. Sensor-Derived Measures of Motor and Cognitive Functions in People With Multiple Sclerosis Using Unsupervised Smartphone-Based Assessments: Proof-of-Concept Study. JMIR Formative Research 2024;8:e60673 View
  12. Yu K, Wu C, Barnes L, Silbert L, Beattie Z, Croff R, Miller L, Dodge H, Kaye J. Life‐Space Mobility Is Related to Loneliness Among Living‐Alone Older Adults: Longitudinal Analysis With Motion Sensor Data. Journal of the American Geriatrics Society 2025;73(4):1125 View
  13. Kaye J, Aisen P, Amariglio R, Au R, Ballard C, Carrillo M, Fillit H, Iwatsubo T, Jimenez-Maggiora G, Lovestone S, Natanegara F, Papp K, Soto M, Weiner M, Vellas B. Using Digital Tools to Advance Alzheimer's Drug Trials During a Pandemic: The EU/US CTAD Task Force. The Journal of Prevention of Alzheimer's Disease 2021;8(4):513 View
  14. Lott S, Streel E, Bachman S, Bode K, Dyer J, Fitzer-Attas C, Goldsack J, Hake A, Jannati A, Fuertes R, Fromy P. Digital Health Technologies for Alzheimer's Disease and Related Dementias: Initial Results from a Landscape Analysis and Community Collaborative Effort. The Journal of Prevention of Alzheimer's Disease 2024;11(5):1480 View
  15. Noda K, Kageyama I, Kobayashi Y, Lim Y, Sengoku S, Kodama K. Leveraging mHealth wearables for managing patients with Alzheimer’s disease: a scoping review. Drug Discovery Today 2025;30(5):104363 View
  16. Kessler D, Irons S, Franz M, Thomas N, Kaye J, Finlayson M, Knoefel F. Codesign of a framework to support compassionate care appropriate to technology use by people with cognitive decline. Disability and Rehabilitation 2025:1 View

Books/Policy Documents

  1. Au R, Lin H, Kolachalama V. Alzheimer's Disease Drug Development. View

Conference Proceedings

  1. Rajkumar A, Wallace B, Ault L, Lariviere-Chartier J, Knoefel F, Goubran R, Kaye J, Thomas N. 2020 IEEE International Conference on Big Data (Big Data). Visualizing Effects of COVID-19 Social Isolation with Residential Activity Big Data Sensor Data View
  2. Agarwal A, Wallace B, Ault L, Lariviere-Chartier J, Knoefel F, Goubran R, Kaye J, Beattie Z, Thomas N. 2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA). Using Zigbee Sensors for Ambient Measurement of Human Gait – Analytical Considerations View
  3. Chimehi B, Larivière-Chartier J, Wallace B, Beattie Z, Ault L, Miller L, Steele J, Thomas N. 2024 IEEE International Symposium on Medical Measurements and Applications (MeMeA). Sensor Assessment of Time in Bed on Caregiver Burden for Person Living with Cognitive Impairment View
  4. Chimehi B, Larivière-Chartier J, Wallace B, Beattie Z, Ault L, Dey R, Sheehy L, Anderson L, Steele J, Thomas N. 2025 IEEE Medical Measurements & Applications (MeMeA). Predicting Caregiver Burden Using Motion Sensor Data and Machine Learning: A Supportive Approach for Persons with Cognitive Decline View