Published on in Vol 8, No 3 (2019): March

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/11868, first published .
Eva Clemens 1, 2*, MSc;  Annelot JM Meijer 1*, MSc;  Linda Broer 3, PhD;  Thorsten Langer 4, MD, PhD;  Anne-Lotte LF van der Kooi 1, 2, 5, MSc, MD;  André G Uitterlinden 3, PhD;  Andrica de Vries 1, 2, MD, PhD;  Claudia E Kuehni 6, 7, MD, PhD;  Maria L Garrè 8, MD;  Tomas Kepak 9, 10, MD;  Jarmila Kruseova 11, MD;  Jeanette F Winther 12, 13, MD;  Leontien C Kremer 1, 14, MD, PhD;  Eline van Dulmen-den Broeder 1, 15, PhD;  Wim JE Tissing 1, 16, MD, PhD;  Catherine Rechnitzer 17, MSc, MD;  Line Kenborg 13, PhD;  Henrik Hasle 18, MD, PhD;  Desiree Grabow 19, PhD;  Ross Parfitt 20, PhD;  Harald Binder 19, 21, PhD;  Bruce C Carleton 22, PharmD;  Julianne Byrne 23, PhD;  Peter Kaatsch 19, PhD;  Antoinette am Zehnhoff-Dinnesen 20, AuD;  Oliver Zolk 24, PhD;  Marry M van den Heuvel-Eibrink 1, MD, PhD

1 Princess Maxima Center for Pediatric Oncology , Utrecht , NL

2 Department of Pediatric Hematology and Oncology , Erasmus Medical Center–Sophia Children's Hospital, Rotterdam , NL

3 Department of Internal Medicine , Erasmus Medical Center, Rotterdam , NL

4 Department of Pediatric Oncology , University Hospital for Children and Adolescents, Luebeck , DE

5 Department of Obstetrics and Gynecology , Erasmus Medical Center–Sophia Children's Hospital, Rotterdam , NL

6 Institute of Social and Preventive Medicine , University of Bern, Bern , CH

7 Department of Paediatric Respiratory Medicine, University Children's Hospital, University of Bern, Bern , CH

8 Department of Neurooncology , Institute Giannina Gaslini, Genova , IT

9 Department of Paediatric Oncology, University Hospital Brno, Masaryk University, Brno , CZ

10 St. Anne’s University Hospital Brno–International Clinical Research Center , Brno , CZ

11 Department of Pediatric Hemato-Oncology , Motol University Hospital Prague, Prague , CZ

12 Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus , DK

13 Danish Cancer Society Research Center , Copenhagen , DK

14 Department of Pediatric Oncology , Academic Medical Center Amsterdam, Amsterdam , NL

15 Department of Pediatric Hematology and Oncology , VU Medical Center, Amsterdam , NL

16 Department of Pediatric Oncology, University Medical Center Groningen, University of Groningen, Groningen , NL

17 Department of Pediatrics and Adolescent Medicine , Copenhagen University Hospital Rigshospitalet, Copenhagen , DK

18 Department of Pediatrics , Aarhus University Hospital, Aarhus , DK

19 German Childhood Cancer Registry, Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz , DE

20 Department of Phoniatrics and Pedaudiology , University of Münster, Muenster , DE

21 Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freibug , DE

22 Division of Translational Therapeutics, Department of Pediatrics, British Columbia Children’s Hospital Research Institute, University of British Columbia, Vancouver, BC, CA

23 Boyne Research Institute , Drogheda , IE

24 Institute of Pharmacology of Natural Products and Clinical Pharmacology , Ulm University Medical Center, Ulm , DE

*these authors contributed equally

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