Protocol Outlines for Parts 1 and 2 of the Prospective Endoscopy III Study for the Early Detection of Colorectal Cancer: Validation of a Concept Based on Blood Biomarkers

Journals

1. Nielsen H, Christensen I, Andersen B, Rasmussen M, Friis-Hansen L, Bygott T, MiCallef J. Serological biomarkers in triage of FIT-positive subjects?. Scandinavian Journal of Gastroenterology 2017;52(6-7):742 View
2. Jensen S, Øgaard N, Ørntoft M, Rasmussen M, Bramsen J, Kristensen H, Mouritzen P, Madsen M, Madsen A, Sunesen K, Iversen L, Laurberg S, Christensen I, Nielsen H, Andersen C. Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation study. Clinical Epigenetics 2019;11(1) View
3. Piper T, Jørgensen L, Olsen J, Nielsen K, Davis G, Johansen J, Jarle Christensen I, Nielsen H. Increased serological, cancer-associated protein biomarker levels at diagnosis of large bowel adenoma: Risk of subsequent primary malignancy?. Acta Oncologica 2019;58(sup1):S42 View
4. Jensen S, Øgaard N, Nielsen H, Bramsen J, Andersen C. Enhanced Performance of DNA Methylation Markers by Simultaneous Measurement of Sense and Antisense DNA Strands after Cytosine Conversion. Clinical Chemistry 2020;66(7):925 View
5. Petersen M, Ferm L, Kleif J, Piper T, Rømer E, Christensen I, Nielsen H. Triage May Improve Selection to Colonoscopy and Reduce the Number of Unnecessary Colonoscopies. Cancers 2020;12(9):2610 View
6. Mertz-Petersen M, Piper T, Kleif J, Ferm L, Christensen I, Nielsen H, Jørgensen L, Rasmussen M, Hendel J, Madsen M, Madsen A, Vilandt J, Hillig T, Willemoes K, Brandsborg S, Klærke M, Andersen B, Hornung N, Sunesen K, Andersen C, Erlandsen E, Kahlid A. Triage for selection to colonoscopy?. European Journal of Surgical Oncology 2018;44(10):1539 View
7. Wilhelmsen M, Christensen I, Jørgensen L, Madsen M, Vilandt J, Hillig T, Klærke M, Nielsen K, Laurberg S, Gawel S, Yang X, Davis G, Heijboer A, Martens F, Nielsen H. Clean Colorectum at Diagnostic Colonoscopy: Subsequent Detection of Extracolonic Malignancies by Plasma Protein Biomarkers?. Biomarkers in Cancer 2018;10 View
8. Ørntoft M, Jensen S, Øgaard N, Henriksen T, Ferm L, Christensen I, Reinert T, Larsen O, Nielsen H, Andersen C. Age‐stratified reference intervals unlock the clinical potential of circulating cell‐free DNA as a biomarker of poor outcome for healthy individuals and patients with colorectal cancer. International Journal of Cancer 2021;148(7):1665 View
9. Bresalier R, Grady W, Markowitz S, Nielsen H, Batra S, Lampe P. Biomarkers for Early Detection of Colorectal Cancer: The Early Detection Research Network, a Framework for Clinical Translation. Cancer Epidemiology, Biomarkers & Prevention 2020;29(12):2431 View
10. Kleif J, Jørgensen L, Hendel J, Madsen M, Vilandt J, Brandsborg S, Andersen L, Khalid A, Ingeholm P, Ferm L, Davis G, Gawel S, Martens F, Andersen B, Rasmussen M, Christensen I, Nielsen H. Early detection of colorectal neoplasia: application of a blood-based serological protein test on subjects undergoing population-based screening. British Journal of Cancer 2022;126(10):1387 View
11. Du X, Aristizabal-Henao J, Garrett T, Brochhausen M, Hogan W, Lemas D. A Checklist for Reproducible Computational Analysis in Clinical Metabolomics Research. Metabolites 2022;12(1):87 View
12. Petersen M, Kleif J, Jørgensen L, Hendel J, Seidelin J, Madsen M, Vilandt J, Brandsborg S, Rasmussen J, Andersen L, Khalid A, Ferm L, Gawel S, Martens F, Andersen B, Rasmussen M, Davis G, Christensen I, Therkildsen C. Optimizing Screening for Colorectal Cancer: An Algorithm Combining Fecal Immunochemical Test, Blood-Based Cancer-Associated Proteins and Demographics to Reduce Colonoscopy Burden. Clinical Colorectal Cancer 2023;22(2):199 View
13. Piper T, Nielsen H, Christensen I. Serological cancer-associated protein biomarker levels at bowel endoscopy: Increased risk of subsequent primary malignancy. Tumor Biology 2022;44(1):1 View
14. Widman A, Shah M, Frydendahl A, Halmos D, Khamnei C, Øgaard N, Rajagopalan S, Arora A, Deshpande A, Hooper W, Quentin J, Bass J, Zhang M, Langanay T, Andersen L, Steinsnyder Z, Liao W, Rasmussen M, Henriksen T, Jensen S, Nors J, Therkildsen C, Sotelo J, Brand R, Schiffman J, Shah R, Cheng A, Maher C, Spain L, Krause K, Frederick D, den Brok W, Lohrisch C, Shenkier T, Simmons C, Villa D, Mungall A, Moore R, Zaikova E, Cerda V, Kong E, Lai D, Malbari M, Marton M, Manaa D, Winterkorn L, Gelmon K, Callahan M, Boland G, Potenski C, Wolchok J, Saxena A, Turajlic S, Imielinski M, Berger M, Aparicio S, Altorki N, Postow M, Robine N, Andersen C, Landau D. Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment. Nature Medicine 2024;30(6):1655 View
15. Petersen M, Kleif J, Liggett J, Rasmussen M, Jørgensen L, Vilandt J, Seidelin J, Beertsen C, Heijboer A, Jaensch C, Bondeven P, Gotschalck K, Løve U, Gawel S, Andersen B, Christensen I, Mayer E, Davis G, Therkildsen C. Development of an algorithm combining blood-based biomarkers, fecal immunochemical test, and age for population-based colorectal cancer screening. Gastrointestinal Endoscopy 2024;100(6):1061 View
16. Øgaard N, Iden C, Jensen S, Mustafa S, Aagaard E, Bramsen J, Ahlborn L, Hasselby J, Rohrberg K, Achiam M, Andersen C, Mau-Sørensen M. DNA methylation markers for sensitive detection of circulating tumor DNA in patients with gastroesophageal cancers. ESMO Gastrointestinal Oncology 2024;6:100104 View