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Published on in Vol 15 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/94288, first published .
Doctor reviews brain MRI scans on a computer monitor, showing detailed axial views of the human brain.

Transcranial Magnetic Stimulation for Patients with Exposure Therapy Resistant Obsessive-Compulsive Disorder (TETRO): Study Protocol for a Multicenter Randomized Controlled Trial

Transcranial Magnetic Stimulation for Patients with Exposure Therapy Resistant Obsessive-Compulsive Disorder (TETRO): Study Protocol for a Multicenter Randomized Controlled Trial

Tjardo S Postma   1, 2, 3, 4 , MD ;   Ysbrand D van der Werf   2, 3 , PhD ;   Martijn Arns   5, 6 , PhD ;   Neeltje M Batelaan   1, 4, 7 , MD, PhD ;   Manou van den Berg   8 , MSc ;   Judith E Bosmans   9 , PhD ;   Merijn Eikelenboom   1 , PhD, LLM ;   Gert-Jan Hendriks   10, 11, 12 , MD, PhD ;   Adriaan W Hoogendoorn   1, 7 , PhD ;   Mirjam Kampman   10, 11 , PhD ;   Désirée van Leeuwen   13 , LLM ;   Iris van Oostrom   8 , PhD ;   Patricia van Oppen   1, 4 , PhD ;   Alexander T Sack   14, 15, 16 , PhD ;   Koen Schruers   17, 18 , MD, PhD ;   Indira Tendolkar   12, 19 , MD, PhD ;   Chris Vriend   1, 2, 3 , PhD ;   Odile A van den Heuvel   1, 2, 3 , MD, PhD

1 Department of Psychiatry, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, North Holland, The Netherlands

2 Department of Anatomy & Neurosciences, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, North Holland, The Netherlands

3 Impulsivity & Attention program, Amsterdam Neuroscience, Amsterdam, North Holland, The Netherlands

4 GGZ inGeest, Amsterdam, North Holland, The Netherlands

5 Brainclinics foundation, Brainclinics, Nijmegen, Gelderland, The Netherlands

6 Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, United States

7 Amsterdam Public Health, Amsterdam, North Holland, The Netherlands

8 Neurocare clinics, Nijmegen, Gelderland, The Netherlands

9 Faculty of Science, Department of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam, North Holland, The Netherlands

10 Overwaal Centre for Anxiety, OCD and PTSD, Pro Persona, Nijmegen, Gelderland, The Netherlands

11 Behavioral Science Institute, Radboud University Nijmegen, Nijmegen, Gelderland, The Netherlands

12 Department of Psychiatry, Radboud University Medical Center, Nijmegen, Gelderland, The Netherlands

13 Angst Dwang en Fobie (ADF) stichting, Driebergen-Rijsenburg, The Netherlands

14 Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Limburg, The Netherlands

15 Maastricht Brain Imaging Centre (MBIC), Maastricht University, Maastricht, Limburg, The Netherlands

16 Brain and Nerve Centre, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, Limburg, The Netherlands

17 Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, Limburg, The Netherlands

18 Topclinical center for anxiety disorders, OCD and PTSD, Mondriaan GGZ, Maastricht, Limburg, The Netherlands

19 Department of Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Gelderland, The Netherlands

Corresponding Author:

  • Odile A van den Heuvel, MD, PhD
  • Department of Psychiatry
  • Amsterdam UMC Location Vrije Universiteit Amsterdam
  • De Boelelaan 1117
  • Amsterdam, North Holland 1081HV
  • The Netherlands
  • Phone: 31 0204444444
  • Email: oa.vandenheuvel@amsterdamumc.nl