Impact of a Personalized Preventive Strategy on Oral Microbial Homeostasis During Fixed Orthodontic Treatment (PREPERMIO): Protocol for a Randomized Controlled Trial

Published on 11.Nov.2026 in Vol 15 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/94212, first published 26.Feb.2026.

; Morgane Ortis¹

; Lilit Tonoyan¹

; Alain Doglio¹

; Marie-France Bertrand^{1, 2}

; Olivier Sorel³

; Laurence Lupi^{1, 2}

Margaux Dubois ^{1, 2} , DDS, PhD ; Morgane Ortis ¹ , PhD ; Lilit Tonoyan ¹ , PhD ; Alain Doglio ¹ , PhD ; Marie-France Bertrand ^{1, 2} , DDS, PhD ; Olivier Sorel ³ , DDS, PhD ; Laurence Lupi ^{1, 2} , DDS, PhD

¹ Laboratoire MICORALIS, Faculté de Chirurgie Dentaire Odontologie, Université Côte d'Azur, Nice, France

² Institut de Médecine Bucco-Dentaire, Centre Hospitalier Universitaire de Nice, Nice, France

³ Private Practice in Orthodontics, Dinan, France

Corresponding Author: