Efficacy and Safety of Shen-Ling-Lian-Xia Granule Combined With Neoadjuvant Chemotherapy in Patients With Triple-Negative Breast Cancer: Protocol for a Randomized, Double-Blind, Multicenter Clinical Trial

Yuanyuan Ren   ^{1, 2 *} , MD ;   Shuai Yuan   ^{3 *} , MD ;   Youyang Shi   ^{2 *} , MD, PhD ;   Lichen Tang   ⁴ , MD ;   Tian Li   ⁵ , MD ;   Rui Yang   ⁶ , MD ;   Kaigang Xie   ⁷ , MD ;   Xiaoqing Zhang   ⁸ , MD ;   Jue Chen   ⁹ , MD ;   Jinhui Hu   ¹⁰ , MD ;   Sheng Liu   ² , MD, PhD

¹ School of Clinical Medicine, Jiangxi University of Chinese Medicine, Jiangxi, China

² Department of Breast Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China

³ International Peace Maternity & Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

⁴ Fudan University Shanghai Cancer Center, Shanghai, China

⁵ Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine (Baoshan Hospital, Shanghai University of Traditional Chinese Medicine), Shanghai, China

⁶ Shanxi Cancer Hospital, Taiyuan, China

⁷ Ningbo Hospital of Integrated Traditional Chinese and Western Medicine, Ningbo, China

⁸ Jiangsu Province Hospital of Traditional Chinese Medicine, Jiangsu, China

⁹ Affiliated Hospital of Yangzhou University, Yangzhou, China

¹⁰ First Affiliated Hospital of Hunan University of Chinese Medicine, Hunan, China

*these authors contributed equally