Evaluation of the TiaoShenZhiAi Regimen for Patients With Ovarian Cancer Experiencing a Psychoneurological Symptom Cluster: Protocol for a Multicenter, Double-Blind, Randomized Controlled Trial

Ze Liu   ^{1, 2 *} , MD ;   Jialiang Yao   ^{1, 2 *} , PhD ;   Xinyi Lu   ^{1, 2} , PhD ;   Yun Yang   ^{1, 2} , PhD ;   Bin Luo   ^{1, 2} , PhD ;   Yanhong Wang   ^{1, 2} , MD ;   Xi Cheng   ³ , PhD, Prof Dr ;   Wei Jiang   ⁴ , PhD, Prof Dr ;   Guowang Yang   ⁵ , PhD, Prof Dr ;   Jing Xiao   ⁶ , PhD, Prof Dr ;   Jiuda Zhao   ⁷ , PhD, Prof Dr ;   Jianhui Tian   ^{1, 2} , PhD, Prof Dr

¹ Clinical Cancer Center, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China

² Oncology Institute of Traditional Chinese Medicine, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai, China

³ Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China

⁴ Department of Gynecologic Oncology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, Shanghai, China

⁵ Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Beijing, Beijing, China

⁶ Department of Gynecology, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong, China

⁷ Breast Disease Diagnosis and Treatment Center, Qinghai University Affiliated Hospital, Xi'ning, Qinghai, China

*these authors contributed equally