Central Nervous System Mechanisms and Treatment Response in Chronic Ocular Surface Pain: Protocol for a Cross-Sectional Observational Phenotyping Study

Lindsey B De Lott   ¹ , MS, MD ;   Steven E Harte   ² , PhD ;   Chelsea Kaplan   ² , PhD ;   David A Williams   ² , PhD ;   Roni Shtein   ¹ , MD ;   Maria A Woodward   ¹ , MD, MSc ;   Alexander Tsodikov   ³ , PhD ;   Tatiana Deveney   ¹ , MD ;   Anat Galor   ^{4, 5} , MD, MPH ;   Anne Shea   ⁶ , MD ;   Charles Schultz   ⁶ , MD ;   Clare McKolay   ¹ , COT ;   Kathy A Scott   ² , BSN, RN ;   Daniel J Clauw   ² , MD

¹ Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, United States

² Chronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, United States

³ Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, United States

⁴ Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States

⁵ Surgical services, Miami Veterans Administration Medical Center, Miami, FL, United States

⁶ Department of Neurology, University of Michigan, Ann Arbor, MI, United States