Unintended Prolonged Opioid Use: Protocol for a Case-Controlled Trial

W Michael Hooten   ^{1 *} , MD ;   Darin J Erickson   ^{2 *} , PhD ;   Marek Chawarski   ^{3 *} , PhD ;   Natalie A Scholz   ^{2 *} , MPH ;   Jennifer F Waljee   ^{4 *} , MPH, MS, MD ;   Chad M Brummett   ^{5 *} , MD ;   Molly M Jeffery   ^{6 *} , PhD

¹ Division of Pain Medicine, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, United States

² Division of Epidemiology and Community Healty, University of Minnesota, Minneapolis, MN, United States

³ Department of Emergency Medicine, Department of Psychiatry, Yale University, New Haven, United States

⁴ Department of Surgery, Indiana University, Bloomington, United States

⁵ Department of Anesthesiology, University of Michigan–Ann Arbor, Ann Arbor, United States

⁶ Division of Health Care Delivery Research, Department of Emergency Medicine, Mayo Clinic, Rochester, MN, United States

*all authors contributed equally