Published on in Vol 14 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/66246, first published .
Evaluating the Efficacy and Safety of 48-Week Low-Dose Dienogest Administration in Patients With Dysmenorrhea Caused by Endometriosis: Protocol for a Randomized, Open-Label, Parallel-Group Trial

Evaluating the Efficacy and Safety of 48-Week Low-Dose Dienogest Administration in Patients With Dysmenorrhea Caused by Endometriosis: Protocol for a Randomized, Open-Label, Parallel-Group Trial

Evaluating the Efficacy and Safety of 48-Week Low-Dose Dienogest Administration in Patients With Dysmenorrhea Caused by Endometriosis: Protocol for a Randomized, Open-Label, Parallel-Group Trial

Kyoko Kikuno   1 , MD ;   Ryuta Asada   2 , PhD ;   Takuma Ishihara   2 , PhD ;   Yoshimasa Bomoto   3 , MD ;   Saki Murase   3 , MD ;   Yoko Ueda   3 , MD ;   Tomomi Shiga   3 , PhD ;   Yoh Hayasaki   3 , MD ;   Tatsuro Furui   3 , PhD ;   Satoko Matsuzaki   4 , MD ;   Masahiko Takemura   4 , PhD ;   Kazutoshi Matsunami   5 , MD ;   Makoto Kubo   6 , MD ;   Naoki Ito   7 , PhD ;   Masanori Isobe   3 , PhD ;   Ken-ichirou Morishige   4 , PhD

1 Department of Obstetrics and Gynecology, Gifu University Medical School Hospital, Gifu, Japan

2 Innovative and Clinical Research Promotion Center, Gifu University Medical School Hospital, Gifu, Japan

3 Department of Obstetrics and Gynecology, Gifu University Medical School Hospital, Gifu, Japan

4 Department of Obstetrics and Gynecology, Osaka General Medical Center, Osaka, Japan

5 Department of Obstetrics and Gynecology, Matsunami General Hospital, Gifu, Japan

6 Department of Obstetrics and Gynecology, Hashima City Hospital, Gifu, Japan

7 Department of Obstetrics and Gynecology, Chuno Kosei Hospital, Gifu, Japan

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