This paper is in the following e-collection/theme issue:

RCTs - Protocols/Proposals (non-eHealth) (443) Cardiology (235) Cardiac Arrhythmia, Atrial Fibrillation (116) Precision Medicine (183) Pharmacology and Pharmaceutics (126) Clinical Information and Decision Making (2041)

Published on in Vol 14 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/44027, first published .
Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial

Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial

Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial

Authors of this article:

Sumanth Karamchand1 Author Orcid Image ;   Tsungai Chipamaunga1 Author Orcid Image ;   Poobalan Naidoo2, 3 Author Orcid Image ;   Kiolan Naidoo4 Author Orcid Image ;   Virendra Rambiritch5 Author Orcid Image ;   Kevin Ho6 Author Orcid Image ;   Robert Chilton7 Author Orcid Image ;   Kyle McMahon8 Author Orcid Image ;   Rory Leisegang9 Author Orcid Image ;   Hellmuth Weich10, 11, 12 Author Orcid Image ;   Karim Hassan13 Author Orcid Image
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Journals

  1. Aazar R, Arzouni R, Nicolaou P. Dual Inhibition of the Renin–Angiotensin–Aldosterone System and Sodium–Glucose Cotransporter-2: Mechanistic and Clinical Evidence for Cardiorenal Protection. Biomedicines 2026;14(1):101 View
  2. Marcin Schulz , Karolina Osińska , Dawid Studziński , Michał Kulczak , Anna Kołcz , Agnieszka Morawa . NEPRILYSIN INHIBITORS (ARNI) IN THE TREATMENT OF CHRONIC HEART FAILURE — A SYSTEMATIC REVIEW AND CRITICAL APPRAISAL OF THE EVIDENCE. International Journal of Innovative Technologies in Social Science 2026;(1(49)) View