Published on in Vol 12 (2023)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/41812, first published .
FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases (FAST-01): Protocol for the First Prospective Feasibility Study

FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases (FAST-01): Protocol for the First Prospective Feasibility Study

FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases (FAST-01): Protocol for the First Prospective Feasibility Study

Journals

  1. Konishi T, Kusumoto T, Hiroyama Y, Kobayashi A, Mamiya T, Kodaira S. Induction of DNA strand breaks and oxidative base damages in plasmid DNA by ultra-high dose rate proton irradiation. International Journal of Radiation Biology 2023;99(9):1405 View
  2. Mascia A, Daugherty E, Breneman J. FLASH Radiotherapy in a Value-Based Health Care Environment—Reply. JAMA Oncology 2023;9(5):727 View
  3. Yang Y, Kang M, Chen C, Hu L, Yu F, Tsai P, Huang S, Liu J, Turner R, Shen B, Hasan S, Chhabra A, Choi J, Bell B, Pennock M, Tome W, Guha C, Simone C, Lin H. Commissioning a 250 MeV research beamline for proton FLASH radiotherapy preclinical experiments. Medical Physics 2023;50(7):4623 View
  4. Yang Y, Kang M, Huang S, Chen C, Tsai P, Hu L, Yu F, Hajj C, Choi J, Tome W, Simone C, Lin H. Impact of respiratory motion on proton pencil beam scanning FLASH radiotherapy: an in silico and phantom measurement study. Physics in Medicine & Biology 2023;68(8):085008 View
  5. Schulte R, Johnstone C, Boucher S, Esarey E, Geddes C, Kravchenko M, Kutsaev S, Loo B, Méot F, Mustapha B, Nakamura K, Nanni E, Obst-Huebl L, Sampayan S, Schroeder C, Sheng K, Snijders A, Snively E, Tantawi S, Van Tilborg J. Transformative Technology for FLASH Radiation Therapy. Applied Sciences 2023;13(8):5021 View
  6. Lattery G, Kaulfers T, Cheng C, Zhao X, Selvaraj B, Lin H, Simone C, Choi J, Chang J, Kang M. Pencil Beam Scanning Bragg Peak FLASH Technique for Ultra-High Dose Rate Intensity-Modulated Proton Therapy in Early-Stage Breast Cancer Treatment. Cancers 2023;15(18):4560 View
  7. Battestini M, Missiaggia M, Attili A, Tommasino F, La Tessa C, Cordoni F, Scifoni E. Across the stages: a multiscale extension of the generalized stochastic microdosimetric model (MS-GSM2) to include the ultra-high dose rate. Frontiers in Physics 2023;11 View
  8. Pennock M, Wei S, Cheng C, Lin H, Hasan S, Chhabra A, Choi J, Bakst R, Kabarriti R, Simone II C, Lee N, Kang M, Press R. Proton Bragg Peak FLASH Enables Organ Sparing and Ultra-High Dose-Rate Delivery: Proof of Principle in Recurrent Head and Neck Cancer. Cancers 2023;15(15):3828 View
  9. Cotterill J, Flynn S, Thomas R, Subiel A, Lee N, Shipley D, Palmans H, Lourenço A. Monte Carlo modelling of a prototype small-body portable graphite calorimeter for ultra-high dose rate proton beams. Physics and Imaging in Radiation Oncology 2023;28:100506 View
  10. Miles D, Sforza D, Wong J, Rezaee M. Dosimetric characterization of a rotating anode x‐ray tube for FLASH radiotherapy research. Medical Physics 2024;51(2):1474 View
  11. Charyyev S, Chang C, Zhu M, Lin L, Langen K, Dhabaan A. Characterization of 250 MeV Protons from the Varian ProBeam PBS System for FLASH Radiation Therapy. International Journal of Particle Therapy 2023;9(4):279 View
  12. Miles D, Sforza D, Wong J, Gabrielson K, Aziz K, Mahesh M, Coulter J, Siddiqui I, Tran P, Viswanathan A, Rezaee M. FLASH Effects Induced by Orthovoltage X-Rays. International Journal of Radiation Oncology*Biology*Physics 2023;117(4):1018 View
  13. Vincini M, Zaffaroni M, Schwarz M, Marvaso G, Mastroleo F, Volpe S, Bergamaschi L, Mazzola G, Corrao G, Orecchia R, Jereczek-Fossa B, Alterio D. More than Five Decades of Proton Therapy: A Bibliometric Overview of the Scientific Literature. Cancers 2023;15(23):5545 View
  14. Harrison N, Kang M, Liu R, Charyyev S, Wahl N, Liu W, Zhou J, Higgins K, Simone C, Bradley J, Dynan W, Lin L. A Novel Inverse Algorithm To Solve the Integrated Optimization of Dose, Dose Rate, and Linear Energy Transfer of Proton FLASH Therapy With Sparse Filters. International Journal of Radiation Oncology*Biology*Physics 2024;119(3):957 View
  15. Ma C, Zhou J, Chang C, Wang Y, Patel P, Yu D, Tian S, Yang X. Streamlined pin‐ridge‐filter design for single‐energy proton FLASH planning. Medical Physics 2024;51(4):2955 View
  16. Kaulfers T, Lattery G, Cheng C, Zhao X, Selvaraj B, Wu H, Chhabra A, Choi J, Lin H, Simone C, Hasan S, Kang M, Chang J. Pencil Beam Scanning Proton Bragg Peak Conformal FLASH in Prostate Cancer Stereotactic Body Radiotherapy. Cancers 2024;16(4):798 View
  17. Borghini A, Labate L, Piccinini S, Panaino C, Andreassi M, Gizzi L. FLASH Radiotherapy: Expectations, Challenges, and Current Knowledge. International Journal of Molecular Sciences 2024;25(5):2546 View
  18. Daugherty E, Zhang Y, Xiao Z, Mascia A, Sertorio M, Woo J, McCann C, Russell K, Sharma R, Khuntia D, Bradley J, Simone C, Breneman J, Perentesis J. FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach. Radiation Oncology 2024;19(1) View
  19. Giannini N, Gadducci G, Fuentes T, Gonnelli A, Di Martino F, Puccini P, Naso M, Pasqualetti F, Capaccioli S, Paiar F. Electron FLASH radiotherapy in vivo studies. A systematic review. Frontiers in Oncology 2024;14 View
  20. Hart A, Giguère C, Bateman J, Korysko P, Farabolini W, Rieker V, Esplen N, Corsini R, Dosanjh M, Beaulieu L, Bazalova-Carter M. Plastic Scintillator Dosimetry of Ultrahigh Dose-Rate 200 MeV Electrons at CLEAR. IEEE Sensors Journal 2024;24(9):14229 View
  21. van Marlen P, van de Water S, Slotman B, Dahele M, Verbakel W. Technical note: Dosimetry and FLASH potential of UHDR proton PBS for small lung tumors: Bragg‐peak‐based delivery versus transmission beam and IMPT. Medical Physics 2024;51(10):7580 View
  22. Tsai P, Yang Y, Wu M, Chen C, Yu F, Simone C, Choi J, Tomé W, Lin H. A comprehensive pre‐clinical treatment quality assurance program using unique spot patterns for proton pencil beam scanning FLASH radiotherapy. Journal of Applied Clinical Medical Physics 2024;25(8) View
  23. Wanstall H, Korysko P, Farabolini W, Corsini R, Bateman J, Rieker V, Hemming A, Henthorn N, Merchant M, Santina E, Chadwick A, Robertson C, Malyzhenkov A, Jones R. VHEE FLASH sparing effect measured at CLEAR, CERN with DNA damage of pBR322 plasmid as a biological endpoint. Scientific Reports 2024;14(1) View
  24. Mossahebi S, Byrne K, Jiang K, Gerry A, Deng W, Repetto C, Jackson I, Sawant A, Poirier Y. A high-throughput focused collimator for OAR-sparing preclinical proton FLASH studies: commissioning and validation. Physics in Medicine & Biology 2024;69(14):14NT01 View
  25. Subiel A, Bourgouin A, Kranzer R, Peier P, Frei F, Gomez F, Knyziak A, Fleta C, Bailat C, Schüller A. Metrology for advanced radiotherapy using particle beams with ultra-high dose rates. Physics in Medicine & Biology 2024;69(14):14TR01 View
  26. Zhao X, Huang S, Lin H, Choi J, Zhu K, Simone C, Yan X, Kang M. A Novel Dose Rate Optimization Method to Maximize Ultrahigh-Dose-Rate Coverage of Critical Organs at Risk Without Compromising Dosimetry Metrics in Proton Pencil Beam Scanning FLASH Radiation Therapy. International Journal of Radiation Oncology*Biology*Physics 2024;120(4):1181 View
  27. Ren W, Hou L, Zhang K, Chen H, Feng X, Jiang Z, Shao F, Dai J, Gao Y, He J. The sparing effect of ultra-high dose rate irradiation on the esophagus. Frontiers in Oncology 2024;14 View
  28. Fischer J, Whitmore L, Desrosiers C, Sheehy S, Bazalova-Carter M. Very high-energy electrons as radiotherapy opportunity. The European Physical Journal Plus 2024;139(8) View
  29. Böhlen T, Psoroulas S, Aylward J, Beddar S, Douralis A, Delpon G, Garibaldi C, Gasparini A, Schüler E, Stephan F, Moeckli R, Subiel A. Recording and reporting of ultra-high dose rate “FLASH” delivery for preclinical and clinical settings. Radiotherapy and Oncology 2024;200:110507 View
  30. Chaikh A, Édouard M, Huet C, Milliat F, Villagrasa C, Isambert A. Towards clinical application of ultra-high dose rate radiotherapy and the FLASH effect: Challenges and current status. Cancer/Radiothérapie 2024;28(5):463 View
  31. Vozenin M, Loo B, Tantawi S, Maxim P, Spitz D, Bailat C, Limoli C. FLASH: New intersection of physics, chemistry, biology, and cancer medicine. Reviews of Modern Physics 2024;96(3) View
  32. Glukhov S, Kuznetsova E. Molecular Mechanisms of FLASH Effect in Radiobiology. Biofizika 2024;69(4):868 View
  33. Bell B, Velten C, Pennock M, Kang M, Tanaka K, Selvaraj B, Bookbinder A, Koba W, Vercellino J, English J, Małachowska B, Pandey S, Duddempudi P, Yang Y, Shajahan S, Hasan S, Choi J, Simone C, Yang W, Tomé W, Lin H, Guha C. Whole Abdominal Pencil Beam Scanned Proton FLASH Increases Acute Lethality. International Journal of Radiation Oncology*Biology*Physics 2024 View
  34. Bancheri J, Currell A, Krasnykh A, Maher M, Lund C, Bui A, Seuntjens J. Evaluation of DSRD-based pulsers for a Dielectric Wall Accelerator. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 2024;1069:169935 View
  35. Snider J, Rustin G, Mayr N, Molitoris J, Chhabra A, Kang M, Simone C, Mossahebi S, Griffin R, Mohiuddin M, Zhang H, Amendola B, Perez N, Tubin S, Limoli C, Marter K, Mahadevan A, Coleman N, Ahmed M. The Radiosurgery Society Working Groups on GRID, LATTICE, Microbeam, and FLASH Radiotherapies: 2022 - 2023 Advancements Symposium and Subsequent Progress Made. Practical Radiation Oncology 2024 View
  36. Pogue B, Thomas W, Tavakkoli A, Jarvis L, Hoopes P. Major contributors to FLASH sparing efficacy emerge from murine skin studies: dose rate, total dose per fraction, anesthesia and oxygenation. Frontiers in Oncology 2024;14 View
  37. Guan F, Jiang D, Wang X, Yang M, Iga K, Li Y, Bronk L, Bronk J, Wang L, Guo Y, Sahoo N, Grosshans D, Koong A, Zhu X, Mohan R. Mimicking large spot‐scanning radiation fields for proton FLASH preclinical studies with a robotic motion platform. Precision Radiation Oncology 2024 View
  38. Feldman J, Pryanichnikov A, Achkienasi A, Polyansky I, Hillman Y, Raskin S, Blumenfeld P, Popovtzer A, Marash M. Commissioning of a novel gantry-less proton therapy system. Frontiers in Oncology 2024;14 View
  39. Alhaddad L, Osipov A, Leonov S. FLASH Radiotherapy: Benefits, Mechanisms, and Obstacles to Its Clinical Application. International Journal of Molecular Sciences 2024;25(23):12506 View
  40. Ma C, Yang X, Setianegara J, Wang Y, Gao Y, Yu D, Patel P, Zhou J. Feasibility study of modularized pin ridge filter implementation in proton FLASH planning for liver stereotactic ablative body radiotherapy. Physics in Medicine & Biology 2024;69(24):245001 View
  41. Cotterill J, Flynn S, Thomas R, Subiel A, Lee N, Homer M, Palmans H, De Marzi L, Prezado Y, Shipley D, Lourenço A. Challenges for the Implementation of Primary Standard Dosimetry in Proton Minibeam Radiation Therapy. Cancers 2024;16(23):4013 View