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Proposals (eHealth) (161) Machine Learning (3125) Artificial Intelligence (4689)
Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/35738, first published .
Grandmother and granddaughter doing yoga tree pose together in a living room.

Life Course Digital Twins–Intelligent Monitoring for Early and Continuous Intervention and Prevention (LifeTIME): Proposal for a Retrospective Cohort Study

Life Course Digital Twins–Intelligent Monitoring for Early and Continuous Intervention and Prevention (LifeTIME): Proposal for a Retrospective Cohort Study

Authors of this article:

Madison Milne-Ives1 Author Orcid Image ;   Lorna K Fraser2 Author Orcid Image ;   Asiya Khan3 Author Orcid Image ;   David Walker3 Author Orcid Image ;   Michelle Helena van Velthoven4 Author Orcid Image ;   Jon May5 Author Orcid Image ;   Ingrid Wolfe6 Author Orcid Image ;   Tracey Harding7 Author Orcid Image ;   Edward Meinert1, 8, 9 Author Orcid Image
Article Authors Cited by (15) Tweetations (3) Metrics

Journals

  1. Calcaterra V, Pagani V, Zuccotti G. Digital Twin: A Future Health Challenge in Prevention, Early Diagnosis and Personalisation of Medical Care in Paediatrics. International Journal of Environmental Research and Public Health 2023;20(3):2181 View
  2. Tretter M, Ott T, Dabrock P. AI-produced certainties in health care: current and future challenges. AI and Ethics 2025;5(1):497 View
  3. Vallée A. Envisioning the Future of Personalized Medicine: Role and Realities of Digital Twins. Journal of Medical Internet Research 2024;26:e50204 View
  4. Maïzi Y, Arcand A, Bendavid Y. Digital twin in healthcare: Classification and typology of models based on hierarchy, application, and maturity. Internet of Things 2024;28:101379 View
  5. Sheng B, Wang Z, Qiao Y, Xie S, Tao J, Duan C. Detecting latent topics and trends of digital twins in healthcare: A structural topic model-based systematic review. DIGITAL HEALTH 2023;9 View
  6. Oulefki A, Amira A, Foufou S. Digital twins and AI transforming healthcare systems through innovation and data-driven decision making. Health and Technology 2025;15(2):299 View
  7. Mishra V, Singh J, Rana S, Haque M. System Dynamics-Based Digital Twin for Population Health- A Case of Diabetes Management in the UAE. Procedia Computer Science 2025;260:252 View
  8. Daraio C, Di Leo S, Orsini J. An Integrated and Flexible Review Framework to Evaluate the Evolution and Barriers of Digital-Twin Technologies in Industrial and Healthcare Domains. Global Journal of Flexible Systems Management 2025;26(3):625 View
  9. Aghamiri S, Amin R. Digital Twin-Based Multiscale Models for Biomarker Discovery in Kinase and Phosphatase Tumorigenic Processes. Kinases and Phosphatases 2025;3(3):18 View
  10. Olawade D, Almarzook S, Ogunbona M, Makanjuola B, Olawuyi O, Wada O. Digital twin applications in healthcare for people living with disability. International Journal of Medical Informatics 2026;212:106359 View
  11. Savvidou D, Dermitzaki N, Baltogianni M, Nikolaou A, Giapros V. Digital Twins in Neonatology: Current Applications and Future Directions: A Narrative Review. Applied Sciences 2026;16(5):2198 View
  12. Taherdoost H. Digital twins to improve clinical trial design and patient satisfaction in oncology. Intelligent Hospital 2026;2(2):100075 View
  13. Silva P, Tao J, Rogers S, He Q, Robert J, Black L, Bruce S, Shireman P, Ramos K. Data Stewardship Barriers to Building Digital Twin Technology for Precision Medicine. AI in Medicine 2026;1(3):20 View

Books/Policy Documents

  1. Barresi G, Gaggioli A, Sternini F, Ravizza A, Pacchierotti C, De Michieli L. mHealth and Human-Centered Design Towards Enhanced Health, Care, and Well-being. View
  2. Kokkas S, Segkouli S, Votis K. Artificial Intelligence Applications and Innovations. AIAI 2025 IFIP WG 12.5 International Workshops. View