This paper is in the following e-collection/theme issue:

RCTs - Protocols/Proposals (non-eHealth) (363)

Published on in Vol 8, No 9 (2019): September

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/13176, first published .
Noninvasive Bimodal Neuromodulation for the Treatment of Tinnitus: Protocol for a Second Large-Scale Double-Blind Randomized Clinical Trial to Optimize Stimulation Parameters

Noninvasive Bimodal Neuromodulation for the Treatment of Tinnitus: Protocol for a Second Large-Scale Double-Blind Randomized Clinical Trial to Optimize Stimulation Parameters

Noninvasive Bimodal Neuromodulation for the Treatment of Tinnitus: Protocol for a Second Large-Scale Double-Blind Randomized Clinical Trial to Optimize Stimulation Parameters

Authors of this article:

Brendan Conlon1, 2, 3 Author Orcid Image ;   Caroline Hamilton2 Author Orcid Image ;   Stephen Hughes2 Author Orcid Image ;   Emma Meade2 Author Orcid Image ;   Deborah A Hall4, 5, 6 Author Orcid Image ;   Sven Vanneste3, 7 Author Orcid Image ;   Berthold Langguth8 Author Orcid Image ;   Hubert H Lim2, 9 Author Orcid Image
Article Authors Cited by (18) Tweetations (7) Metrics

Journals

  1. Kleinjung T, Langguth B. Avenue for Future Tinnitus Treatments. Otolaryngologic Clinics of North America 2020;53(4):667 View
  2. Langguth B. Non-Invasive Neuromodulation for Tinnitus. Journal of Audiology and Otology 2020;24(3):113 View
  3. Conlon B, Langguth B, Hamilton C, Hughes S, Meade E, Connor C, Schecklmann M, Hall D, Vanneste S, Leong S, Subramaniam T, D’Arcy S, Lim H. Bimodal neuromodulation combining sound and tongue stimulation reduces tinnitus symptoms in a large randomized clinical study. Science Translational Medicine 2020;12(564) View
  4. Mazurek B, Hesse G, Sattel H, Kratzsch V, Lahmann C, Dobel C. S3 Guideline: Chronic Tinnitus. HNO 2022;70(11):795 View
  5. Grundfast K, Jamil T. Evaluation and Management of Tinnitus: Are There Opportunities for Improvement?. Otolaryngology–Head and Neck Surgery 2023;168(1):45 View
  6. Conlon B, Hamilton C, Meade E, Leong S, O Connor C, Langguth B, Vanneste S, Hall D, Hughes S, Lim H. Different bimodal neuromodulation settings reduce tinnitus symptoms in a large randomized trial. Scientific Reports 2022;12(1) View
  7. Sirh S, Sirh S, Mun H, Sirh H. Integrative Treatment for Tinnitus Combining Repeated Facial and Auriculotemporal Nerve Blocks With Stimulation of Auditory and Non-auditory Nerves. Frontiers in Neuroscience 2022;16 View
  8. Mercante B, Enrico P, Deriu F. Cognitive Functions following Trigeminal Neuromodulation. Biomedicines 2023;11(9):2392 View
  9. Ying B, Huang H, Su Y, Howarth J, Gu Z, Nan K. Theranostic gastrointestinal residence systems. Device 2023;1(2):100053 View
  10. Singh A, Smith P, Zheng Y. Targeting the Limbic System: Insights into Its Involvement in Tinnitus. International Journal of Molecular Sciences 2023;24(12):9889 View
  11. Yasoda-Mohan A, Adcock K, Leong S, Meade E, Langguth B, Schecklmann M, Lim H, Vanneste S. Tinnitus: A Dimensionally Segregated, yet Perceptually Integrated Heterogeneous Disorder. Journal of the Association for Research in Otolaryngology 2024;25(2):215 View
  12. Adcock K, Byczynski G, Meade E, Leong S, Gault R, Lim H, Vanneste S. Feasibility of deep learning to predict tinnitus patient outcomes. Intelligence-Based Medicine 2024;9:100141 View
  13. Boedts M, Buechner A, Khoo S, Gjaltema W, Moreels F, Lesinski-Schiedat A, Becker P, MacMahon H, Vixseboxse L, Taghavi R, Lim H, Lenarz T. Combining sound with tongue stimulation for the treatment of tinnitus: a multi-site single-arm controlled pivotal trial. Nature Communications 2024;15(1) View
  14. McMahan E, Lim H. Retrospective chart review demonstrating effectiveness of bimodal neuromodulation for tinnitus treatment in a clinical setting. Communications Medicine 2025;5(1) View
  15. Raeisi Z, Sodagartojgi A, Sharafkhani F, Roshanzamir A, Najafzadeh H, Bashiri O, Golkarieh A. Enhanced classification of tinnitus patients using EEG microstates and deep learning techniques. Scientific Reports 2025;15(1) View

Books/Policy Documents

  1. Riffle T, Martel D, Jones G, Shore S. The Behavioral Neuroscience of Tinnitus. View
  2. De Ridder D, Adhia D, Langguth B. The Behavioral Neuroscience of Tinnitus. View
  3. Noreña A, Lacher-Fougère S, Fraysse M, Bizaguet E, Grevin P, Thai-Van H, Moati L, Le Pajolec C, Fournier P, Ohresser M. Tinnitus - An Interdisciplinary Approach Towards Individualized Treatment: Towards understanding the complexity of tinnitus. View