A Prospective, Multicenter, Randomized Phase II Study to Evaluate the Efficacy and Safety of Eculizumab in Patients with Guillain-Barré Syndrome (GBS): Protocol of Japanese Eculizumab Trial for GBS (JET-GBS)

Nobuko Yamaguchi   ¹ , BSc ;   Sonoko Misawa   ² , PhD, MD ;   Yasunori Sato   ³ , PhD ;   Kengo Nagashima   ³ , PhD ;   Kanako Katayama   ¹ , MSc ;   Yukari Sekiguchi   ² , PhD, MD ;   Yuta Iwai   ² , PhD, MD ;   Hiroshi Amino   ² , MD ;   Tomoki Suichi   ² , MD ;   Takanori Yokota   ⁴ , PhD, MD ;   Yoichiro Nishida   ⁴ , PhD, MD ;   Nobuo Kohara   ⁵ , PhD, MD ;   Koichi Hirata   ⁶ , PhD, MD ;   Kazutoshi Nishiyama   ⁷ , PhD, MD ;   Ichiro Yabe   ⁸ , PhD, MD ;   Ken-Ichi Kaida   ⁹ , PhD, MD ;   Norihiro Suzuki   ¹⁰ , PhD, MD ;   Hiroyuki Nodera   ¹¹ , MD ;   Shoji Tsuji   ¹² , PhD, MD ;   Haruki Koike   ¹³ , PhD, MD ;   Jun-Ichi Kira   ¹⁴ , PhD, MD ;   Hideki Hanaoka   ¹ , PhD, MD ;   Susumu Kusunoki   ¹⁵ , PhD, MD ;   Satoshi Kuwabara   ² , PhD, MD ;   JET-GBS Group   ^{4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15}

¹ Reseach and Education Center of Health Sciences, Gunma University Graduate School of Health Sciences, Gunma, JP

² Department of Neurology, Chiba University Graduate School of Medicine, Chiba, JP

³ Department of Global Clinical Research, Chiba University Graduate School of Medicine, Chiba, JP

⁴ Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Tokyo, JP

⁵ Department of Neurology, Kobe City Medical Centre General Hospital, Kobe, JP

⁶ Department of Neurology, Dokkyo Medical University, Tochigi, JP

⁷ Department of Neurology, Kitasato University School of Medicine, Kanagawa, JP

⁸ Department of Neurology, Hokkaido University Graduate School of Medicine, Sapporo, JP

⁹ Division of Neurology, Department of Internal Medicine, National Defense Medical College, Saitama, JP

¹⁰ Department of Neurology, Keio University School of Medicine, Tokyo, JP

¹¹ Department of Clinical Neuroscience, Graduate School of Medical Sciences, Tokushima University, Tokushima, JP

¹² Department of Neurology, The University of Tokyo Graduate School of Medicine, Tokyo, JP

¹³ Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, JP

¹⁴ Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JP

¹⁵ Department of Neurology, Faculty of Medicine, Kindai University, Osaka-Sayama, JP