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The Paget Trial: A Multicenter, Observational Cohort Intervention Study for the Clinical Efficacy, Safety, and Immunological Response of Topical 5% Imiquimod Cream for Vulvar Paget Disease

The Paget Trial: A Multicenter, Observational Cohort Intervention Study for the Clinical Efficacy, Safety, and Immunological Response of Topical 5% Imiquimod Cream for Vulvar Paget Disease

Vulvar clinics are outpatient multidisciplinary clinics with participation of both gynecologists and dermatologists who are specialized in disorders of the vulva.Participating centers are Antoni van Leeuwenhoek, Netherlands Cancer Institute, Amsterdam; Catharina

Michelle van der Linden, Kim Meeuwis, Colette van Hees, Eleonora van Dorst, Johan Bulten, Tjalling Bosse, Joanna IntHout, Dorry Boll, Brigitte Slangen, Manon van Seters, Marc van Beurden, Mariëtte van Poelgeest, Joanne de Hullu

JMIR Res Protoc 2017;6(9):e178


Treatment of Peritoneal Dissemination in Stomach Cancer Patients With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Rationale and Design of the PERISCOPE Study

Treatment of Peritoneal Dissemination in Stomach Cancer Patients With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Rationale and Design of the PERISCOPE Study

survival will be measured from the date of start of systemic chemotherapy to the date of disease recurrence and/or death.Ethical ConsiderationsThe study protocol has been approved by the medical ethical committee of the Netherlands Cancer Institute/Antoni van

Rosa T van der Kaaij, Hidde JW Braam, Henk Boot, Maartje Los, Annemieke Cats, Cecile Grootscholten, Jan HM Schellens, Arend GJ Aalbers, Alwin DR Huitema, Catherijne AJ Knibbe, Djamila Boerma, Marinus J Wiezer, Bert van Ramshorst, Johanna W van Sandick

JMIR Res Protoc 2017;6(7):e136


Development of a Self-Help Web-Based Intervention Targeting Young Cancer Patients With Sexual Problems and Fertility Distress in Collaboration With Patient Research Partners

Development of a Self-Help Web-Based Intervention Targeting Young Cancer Patients With Sexual Problems and Fertility Distress in Collaboration With Patient Research Partners

If the intervention is shown to be effective, it is planned to be implemented in regular care.The Holistic Framework for Development of eHealth TechnologiesThis study is based on the holistic framework for developing eHealth technologies by van Gemert-Pijnen

Jeanette Winterling, Maria Wiklander, Claire Micaux Obol, Claudia Lampic, Lars E Eriksson, Britta Pelters, Lena Wettergren

JMIR Res Protoc 2016;5(2):e60


Neurofeedback as a Treatment for Impulsivity in a Forensic Psychiatric Population With Substance Use Disorder: Study Protocol of a Randomized Controlled Trial Combined With an N-of-1 Clinical Trial

Neurofeedback as a Treatment for Impulsivity in a Forensic Psychiatric Population With Substance Use Disorder: Study Protocol of a Randomized Controlled Trial Combined With an N-of-1 Clinical Trial

It has been approved by the medical ethical council of Brabant, the Netherlands (study number NL46390.008.13).This study takes place in Forensic Psychiatric Centre (FPC) Dr S van Mesdag, a maximum security inpatient forensic treatment facility in Groningen,

Sandra Fielenbach, Franc CL Donkers, Marinus Spreen, Stefan Bogaerts

JMIR Res Protoc 2017;6(1):e13


Systematic Evaluation of Research Progress on Natural Language Processing in Medicine Over the Past 20 Years: Bibliometric Study on PubMed

Systematic Evaluation of Research Progress on Natural Language Processing in Medicine Over the Past 20 Years: Bibliometric Study on PubMed

It was codeveloped by Nees Jan van Eck and Ludo Waltman of Leiden University in the Netherlands [29], and it has unique advantages in clustering techniques based on co-occurrences.

Jing Wang, Huan Deng, Bangtao Liu, Anbin Hu, Jun Liang, Lingye Fan, Xu Zheng, Tong Wang, Jianbo Lei

J Med Internet Res 2020;22(1):e16816


Authors’ Reply to: Comment on “Feasibility of a New Cuffless Device for Ambulatory Blood Pressure Measurement in Patients With Hypertension: Mixed Methods Study”

Authors’ Reply to: Comment on “Feasibility of a New Cuffless Device for Ambulatory Blood Pressure Measurement in Patients With Hypertension: Mixed Methods Study”

We thank Noud van Helmond and colleagues [1] for the critical assessment of our study results.In a number of studies, we have recently evaluated the possible value of a handy device (Viatom’s Checkme) for measuring multiple vital parameters, including cuffless

Sebastian J H Bredie, Jelske M de Jong, Tom H van de Belt, Harry van Goor

J Med Internet Res 2020;22(4):e16205


Adaptive Elements in Internet-Delivered Psychological Treatment Systems: Systematic Review

Adaptive Elements in Internet-Delivered Psychological Treatment Systems: Systematic Review

Os et al, 2017 [55]van de Ven et al, 2017 [32]Intervention PlatformBased on our findings, the communication media used to administer internet-facilitated interventions to patients can be classified into three categories: web apps, mobile apps, and computer

Suresh Kumar Mukhiya, Jo Dugstad Wake, Yavuz Inal, Ka I Pun, Yngve Lamo

J Med Internet Res 2020;22(11):e21066