<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="research-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIR Res Protoc</journal-id><journal-id journal-id-type="publisher-id">ResProt</journal-id><journal-id journal-id-type="index">5</journal-id><journal-title>JMIR Research Protocols</journal-title><abbrev-journal-title>JMIR Res Protoc</abbrev-journal-title><issn pub-type="epub">1929-0748</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v15i1e83495</article-id><article-id pub-id-type="doi">10.2196/83495</article-id><article-categories><subj-group subj-group-type="heading"><subject>Protocol</subject></subj-group></article-categories><title-group><article-title>Salutogenesis in Mexico and Latin America: Protocol For Scoping Review</article-title></title-group><contrib-group><contrib contrib-type="author" equal-contrib="yes"><name name-style="western"><surname>Ramos Herrera</surname><given-names>Igor Martin</given-names></name><degrees>MD, PhD</degrees><xref ref-type="aff" rid="aff1"/><xref ref-type="fn" rid="equal-contrib1">*</xref></contrib><contrib contrib-type="author" corresp="yes" equal-contrib="yes"><name name-style="western"><surname>Cisneros Garcia</surname><given-names>Rigoberto Antonio</given-names></name><degrees>MGSSS, LE, MPSS</degrees><xref ref-type="aff" rid="aff1"/><xref ref-type="fn" rid="equal-contrib1">*</xref></contrib></contrib-group><aff id="aff1"><institution>Department of Public Health, University of Guadalajara, Regional Institute for Public Health Research</institution><addr-line>Sierra Mojada 950, Colonia Independencia</addr-line><addr-line>Guadalajara</addr-line><country>Mexico</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Schwartz</surname><given-names>Amy</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Girma</surname><given-names>Abayeneh</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Rigoberto Antonio Cisneros Garcia, MGSSS, LE, MPSS, Department of Public Health, University of Guadalajara, Regional Institute for Public Health Research, Sierra Mojada 950, Colonia Independencia, Guadalajara, 44340, Mexico, 52 (33) 1058 5200 ext 33902; <email>rigoberto.cisneros@academicos.udg.mx</email></corresp><fn fn-type="equal" id="equal-contrib1"><label>*</label><p>all authors contributed equally</p></fn></author-notes><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>16</day><month>4</month><year>2026</year></pub-date><volume>15</volume><elocation-id>e83495</elocation-id><history><date date-type="received"><day>08</day><month>09</month><year>2025</year></date><date date-type="rev-recd"><day>13</day><month>03</month><year>2026</year></date><date date-type="accepted"><day>16</day><month>03</month><year>2026</year></date></history><copyright-statement>&#x00A9; Igor Martin Ramos Herrera, Rigoberto Antonio Cisneros Garcia. Originally published in JMIR Research Protocols (<ext-link ext-link-type="uri" xlink:href="https://www.researchprotocols.org">https://www.researchprotocols.org</ext-link>), 16.4.2026. </copyright-statement><copyright-year>2026</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Research Protocols, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://www.researchprotocols.org">https://www.researchprotocols.org</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://www.researchprotocols.org/2026/1/e83495"/><abstract><sec><title>Background</title><p>The salutogenic model, introduced by Aaron Antonovsky, represents a fundamental paradigm shift from the traditional pathogenic orientation&#x2014;which focuses on the etiology of disease&#x2014;to a focus on the origins of health (salutogenesis). The core of this model is the Sense of Coherence, a global orientation that allows individuals to mobilize Generalized Resistance Resources to cope with the stressors of daily life. Although salutogenesis has been extensively researched in Europe and North America, its systematic application within diverse and multicultural contexts, marked by the inequity present in Mexico and Latin America, remains fragmented and insufficiently documented. There is a lack of clarity regarding how the model adapts to local realities, specifically in these countries.</p></sec><sec><title>Objective</title><p>The main objective of this study is to conduct a scoping review to systematically map the extent, range, and nature of research activity on salutogenesis in Mexico and Latin America published between 2010 and 2026. Secondary objectives include identifying the theoretical frameworks employed, describing the psychometric properties of the instruments used to study the Sense of Coherence model in Spanish, English, and Portuguese, as well as determining research gaps to identify future guidelines for health promotion.</p></sec><sec sec-type="methods"><title>Methods</title><p>This review will adhere to the methodological framework for scoping reviews developed by Arksey and O&#x2019;Malley, refined by Levac et al, and the guidelines of the Joanna Briggs Institute. The protocol adheres to the PRISMA criteria for Scoping Reviews (PRISMA-ScR). A trilingual search (ie, English, Spanish, Portuguese) will be conducted in MEDLINE (PubMed), Scopus, Web of Science, PsycINFO, CINAHL, SciELO, LILACS, and Redalyc. Two independent reviewers will screen titles or abstracts and full-text articles, evaluating inter-rater reliability using Cohen Kappa coefficient. Data will be extracted using a piloted form and synthesized through descriptive numerical analysis and qualitative thematic analysis.</p></sec><sec sec-type="results"><title>Results</title><p>This protocol did not involve funding. The search strategy was finalized and preliminary searches were conducted in August 2025. Starting in February 2026, the study will begin the data integration phase. The final analysis is expected to be completed by August 2026, with submission for publication planned for December 2026.</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>This scoping review will be the first to provide a holistic view of salutogenic research in Latin America. By synthesizing the evidence on how the model is operationalized in this region, the study will provide critical insights for the transition of public health systems from a curative model to one that fosters health assets, supporting the design of culturally congruent interventions.</p></sec><sec sec-type="registered-report"><title>International Registered Report Identifier (IRRID)</title><p>PRR1-10.2196/83495</p></sec></abstract><kwd-group><kwd>salutogenesis</kwd><kwd>Mexico</kwd><kwd>Latin America</kwd><kwd>public health</kwd><kwd>scoping review</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><sec id="s1-1"><title>The Hegemony of the Pathogenic Paradigm</title><p>For centuries, biomedical sciences have been dominated by the pathogenic paradigm. This perspective asks, &#x201C;Why do people get sick?&#x201D; and focuses its resources on identifying pathogens, risk factors, and treating specific diseases [<xref ref-type="bibr" rid="ref1">1</xref>]. While this approach has been responsible for monumental achievements in human survival&#x2014;such as the eradication of smallpox and the management of infectious diseases&#x2014;it inherently views health as a dichotomous variable (ie, the presence or absence of disease). Under this model, the goal of public health is to return the individual to a state of &#x201C;normality&#x201D; or homeostasis, largely defined by the absence of pathology [<xref ref-type="bibr" rid="ref2">2</xref>]. However, this &#x201C;deficit model&#x201D; fails to explain why despite given the omnipresence of viruses, bacteria, stressors, and socioeconomic challenges, a significant portion of the population remains healthy and thrives.</p></sec><sec id="s1-2"><title>The Salutogenic Turn</title><sec id="s1-2-1"><title>Origins of Health</title><p>In the late 1970s, medical sociologist Aaron Antonovsky challenged this orthodoxy by introducing the concept of Salutogenesis (from the Latin <italic>salus</italic>=health, and the Greek <italic>genesis</italic>=origin). Antonovsky posited that chaos and stress are inherent to the human condition, not deviations from the norm. He proposed the &#x201C;Health Ease/Dis-ease Continuum,&#x201D; suggesting that individuals are not simply &#x201C;healthy&#x201D; or &#x201C;sick,&#x201D; but constantly moving along a spectrum between total health and breakdown [<xref ref-type="bibr" rid="ref3">3</xref>]. The relevant question then shifts from &#x201C;how do we treat disease?&#x201D; to &#x201C;how can we help a person move toward the health pole on the continuum, regardless of their current physiological state?&#x201D;</p></sec><sec id="s1-2-2"><title>Theoretical Core</title><p>The cornerstone of the salutogenic model is the Sense of Coherence (SOC). Antonovsky defined SOC as: &#x201C;a global orientation that expresses the extent to which one has a pervasive, enduring though dynamic feeling of confidence.&#x201D; This construct consists of three interrelated components:</p><list list-type="order"><list-item><p>Comprehensibility (Cognitive): The belief that stimuli deriving from internal and external environments are structured, predictable, and explicable.</p></list-item><list-item><p>Manageability (Instrumental): The perception that resources are available to meet the demands posed by these stimuli.</p></list-item><list-item><p>Meaningfulness (Motivational): The sense that these demands are challenges worthy of emotional investment and engagement.</p></list-item></list><p>Research suggests that people with a strong SOC are better able to identify and mobilize Generalized Resistance Resources (GRRs)&#x2014;such as money, ego strength, social support, and cultural stability&#x2014;to cope with stressors effectively, thereby maintaining or improving their health.</p></sec></sec><sec id="s1-3"><title>The Latin American Context</title><sec id="s1-3-1"><title>A Unique Epidemiological Landscape</title><p>While the salutogenic model has been widely adopted in the Global North, specifically in Scandinavia, the United States, and Israel, its application in Latin America warrants specific investigation. For its part, the Latin American region is characterized by deep structural inequalities, rapid urbanization, and a polarized epidemiological profile where chronic non-communicable diseases (diabetes, hypertension, etc) coexist with infectious diseases and violence [<xref ref-type="bibr" rid="ref4">4</xref>].</p><p>Furthermore, Latin America has a rich history of &#x201C;Social Medicine&#x201D; and &#x201C;Collective Health,&#x201D; which share philosophical roots with salutogenesis but have developed independently. Concepts such as <italic>Buen Vivir</italic> (Sumak Kawsay) in the Andean region emphasize harmony with the community and nature as a prerequisite for health, coinciding with the holistic nature of salutogenesis [<xref ref-type="bibr" rid="ref5">5</xref>]. However, it is unclear to what extent Europe-derived salutogenic instruments (such as the SOC-29 or SOC-13 questionnaires) are culturally valid in these contexts, or whether they capture the nuances of Latin American resilience.</p></sec><sec id="s1-3-2"><title>Rationale for a Scoping Review</title><p>Given the potential fragmentation of the literature in this region&#x2014;scattered across psychology, public health, nursing, and sociology journals, and often published in Spanish or Portuguese&#x2014;a classic systematic review focusing on intervention effectiveness would be premature. A scoping review is the most appropriate methodology to: (a) map the volume of research activity in the region, (b) clarify concepts and definitions used in the local literature, (c) identify research gaps (eg, lack of qualitative studies, absence of intervention studies), and (d) synthesize the evidence to inform the feasibility of a future full systematic review [<xref ref-type="bibr" rid="ref6">6</xref>].</p><p>To the best of our knowledge, no comprehensive scoping review has specifically addressed the production of salutogenic knowledge in Mexico and Latin America. This protocol outlines the rigorous steps we will take to address this gap.</p></sec></sec></sec><sec id="s2" sec-type="methods"><title>Methods</title><sec id="s2-1"><title>Study Design and Registration</title><p>This scoping review will be conducted according to the methodological framework originally proposed by Arksey and O&#x2019;Malley [<xref ref-type="bibr" rid="ref7">7</xref>] and later enhanced by Levac, Colquhoun, and O&#x2019;Brien [<xref ref-type="bibr" rid="ref8">8</xref>]. Additionally, we will follow the guidance provided by the Joanna Briggs Institute (JBI) Manual for Evidence Synthesis [<xref ref-type="bibr" rid="ref9">9</xref>].</p><p>The methodology consists of five key stages: (1) identifying the research question, (2) identifying relevant studies, (3) study selection, (4) data charting, and (5) collating, summarizing, and reporting the results.</p><sec id="s2-1-1"><title>Stage 1: Identifying the Research Questions</title><p>We used the PCC (Population, Concept and Context) mnemonic recommended by the JBI to construct the research questions:</p><list list-type="bullet"><list-item><p>Population human populations with no restriction on age, gender, or health status (eg, patients, students, health professionals) [<xref ref-type="bibr" rid="ref10">10</xref>]</p></list-item><list-item><p>Concept: Salutogenesis, SOC, Generalized Resistance Resources (GRRs)</p></list-item><list-item><p>Context: Research conducted in Mexico, Central America, South America, and the Spanish/Portuguese-speaking Caribbean</p></list-item></list></sec><sec id="s2-1-2"><title>Primary Research Question</title><p>What is the current state of scientific knowledge regarding salutogenesis and the SOC in Mexico and Latin America from 2010 to 2026?</p></sec><sec id="s2-1-3"><title>Secondary Questions</title><p>What theoretical frameworks and definitions of salutogenesis are employed in Latin American research? Which versions of the SOC scale (SOC-13, SOC-29, or adapted versions) are most frequently used and have been validated for specific local populations? What are the main health outcomes (mental health, chronic disease management, health behaviors) associated with salutogenesis in the region? In what settings (clinical, educational, community, occupational) [<xref ref-type="bibr" rid="ref11">11</xref>]. Is the model being applied?</p></sec></sec><sec id="s2-2"><title>Stage 2: Identifying Relevant Studies</title><p>A comprehensive search strategy will be implemented to locate both published and gray literature. The search will be limited to documents published between January 1, 2010, and December 31, 2025, to capture the most recent developments and the evolution of the field over the last 15 years.</p><sec id="s2-2-1"><title>Information Sources</title><p>We will search the following electronic databases through access licenses provided by the University of Guadalajara, Mexico:</p></sec><sec id="s2-2-2"><title>International Databases</title><p>MEDLINE (via PubMed), Scopus (Elsevier), Web of Science (Core Collection), PsycINFO (APA), and CINAHL (EBSCOhost).</p></sec><sec id="s2-2-3"><title>Regional Databases</title><list list-type="bullet"><list-item><p>SciELO (Scientific Electronic Library Online): covers a vast network of Latin American journals</p></list-item><list-item><p>LILACS (Latin American and Caribbean Health Sciences Literature): The most comprehensive index of scientific and technical literature in the region</p></list-item><list-item><p>Redalyc (Network of Scientific Journals of Latin America and the Caribbean, Spain and Portugal): A major open-access database of peer-reviewed journals from Latin America, Spain, and Portugal</p></list-item></list></sec><sec id="s2-2-4"><title>Search Strategy</title><p>The search strategy will use a combination of controlled vocabulary (MeSH terms for PubMed, DeCS terms for LILACS/SciELO) and free-text keywords. The search will be conducted in English, Spanish, and Portuguese.</p><list list-type="bullet"><list-item><p xml:lang="es-mx"><bold>Keywords (English):</bold> &#x201C;Salutogenesis,&#x201D; &#x201C;Sense of Coherence,&#x201D;&#x201C;Sense of Coherence,&#x201D; &#x201C;Salutogenic,&#x201D; &#x201C;Generalized Resistance Resources,&#x201D;&#x201C;Generalized Resistance Resources,&#x201D; &#x201C;Latin America,&#x201D; &#x201C;Mexico,&#x201D; &#x201C;Brazil,&#x201D; &#x201C;Argentina,&#x201D; &#x201C;Colombia,&#x201D; &#x201C;Chile,&#x201D; &#x201C;Peru,&#x201D; &#x201C;Central America,&#x201D; &#x201C;South America.&#x201D;</p></list-item><list-item><p xml:lang="es-mx"><bold>Keywords (Spanish):</bold> &#x201C;Salutog&#x00E9;nesis,&#x201D; &#x201C;Sentido de Coherencia,&#x201D; &#x201C;Modelo Salutog&#x00E9;nico,&#x201D; &#x201C;Recursos Generales de Resistencia,&#x201D; &#x201C;Am&#x00E9;rica Latina,&#x201D; &#x201C;M&#x00E9;xico.&#x201D;</p></list-item><list-item><p xml:lang="es-mx"><bold>Keywords (Portuguese):</bold> &#x201C;Salutog&#x00EA;nese,&#x201D; &#x201C;Senso de Coer&#x00EA;ncia,&#x201D; &#x201C;Recursos Gerais de Resist&#x00EA;ncia,&#x201D; &#x201C;Am&#x00E9;rica Latina.&#x201D;</p></list-item></list><p>A draft of the search strategy for PubMed is provided in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p></sec><sec id="s2-2-5"><title>Gray Literature Strategy</title><p>To minimize publication bias, we will search for gray literature in:</p><p><bold>Google Scholar (reviewing the first 200 results):</bold> A broad multidisciplinary search engine that retrieves scholarly literature across formats, useful for capturing a wide range of academic sources</p><p><bold>Institutional repositories of major Latin American universities (e.g., UNAM, University of S&#x00E3;o Paulo, University of Guadalajara):</bold> University-based repositories that provide access to theses, dissertations, articles, and other academic outputs produced by institutional researchers and students</p><p><bold>ProQuest Dissertations and Theses:</bold> A major database of graduate theses and dissertations, offering access to extensive scholarly work from universities worldwide</p></sec></sec><sec id="s2-3"><title>Stage 3: Study Selection</title><p>This process will be managed using Covidence (Veritas Health Innovation) or Rayyan software to ensure transparency and blinding.</p><sec id="s2-3-1"><title>Inclusion Criteria</title><list list-type="bullet"><list-item><p>Study type: Primary empirical studies (quantitative, qualitative, mixed), systematic reviews, meta-analyses, and theoretical articles proposing specific adaptations for the region [<xref ref-type="bibr" rid="ref12">12</xref>]</p></list-item><list-item><p>Language: Spanish, English, or Portuguese</p></list-item><list-item><p>Topic: The study must explicitly address salutogenesis or measure the SOC as a primary variable</p></list-item><list-item><p>Geography: Conducted in Latin American countries</p></list-item></list></sec><sec id="s2-3-2"><title>Exclusion Criteria</title><list list-type="bullet"><list-item><p>Editorials, commentaries, and opinion pieces without original data or theoretical contribution</p></list-item><list-item><p>Conference abstracts where the full text is not available</p></list-item><list-item><p>Studies conducted on Latin American immigrants residing outside the region (eg, in the USA or Spain), as the environmental context differs from the scope of this review</p></list-item></list></sec></sec><sec id="s2-4"><title>Screening Process</title><sec id="s2-4-1"><title>Calibration</title><p>Before starting the formal screening, the two reviewers (IMRH and RACG) will independently evaluate a random sample of 50 citations. We will calculate inter-rater reliability using Cohen&#x2019;s Kappa coefficient. If Kappa&#x003C;0.75, reviewers will discuss discrepancies and refine the inclusion criteria.</p></sec><sec id="s2-4-2"><title>Level 1 Screening (Title and Abstract)</title><p>Two reviewers will independently examine all retrieved citations.</p></sec><sec id="s2-4-3"><title>Level 2 Screening (Full Text):</title><p>The full text of potentially eligible articles will be retrieved and evaluated independently. Reasons for exclusion will be recorded for each article rejected at this stage. Discrepancy Resolution: Any disagreement will be resolved through discussion or by consulting a third senior reviewer if consensus cannot be reached.</p></sec></sec><sec id="s2-5"><title>Stage 4: Data Charting</title><p>A data extraction form will be developed in Microsoft Excel. The form will be iteratively updated; the two reviewers will pilot test the form on a sample of 5&#x2010;10 studies to ensure it captures all necessary nuances.</p><p>The data items to be extracted include:</p><list list-type="order"><list-item><p>Bibliometric data: Author(s), year, title, journal, country of origin, publication language</p></list-item><list-item><p>Methodological data: Study design (eg, cross-sectional, cohort, ethnographic), sample size, sampling method, study duration</p></list-item><list-item><p>Population characteristics: Age group (children, adolescents, adults, elderly), gender distribution, socioeconomic status, health status (healthy vs clinical population)</p></list-item></list><sec id="s2-5-1"><title>Salutogenic Variables</title><p>The methodology framework begins with a clear definition of salutogenesis tailored to the study&#x2019;s context. To quantify the SOC, researchers utilized established instruments such as the SOC-13, SOC-29, SOC-L, or the Family SOC scale. Furthermore, the study details the reliability coefficients (Cronbach &#x03B1;) specifically calculated for the local population to ensure psychometric integrity. Finally, the analysis incorporates additional salutogenic constructs, specifically Generalized Resistance Resources (GRRs).</p></sec><sec id="s2-5-2"><title>Main Findings</title><p>The main findings included associations between SOC and health outcomes, as well as the main themes identified in qualitative studies. Conclusions included the authors&#x2019; recommendations for policy or practice.</p></sec></sec><sec id="s2-6"><title>Stage 5: Collating, Summarizing, and Reporting Results</title><p>We will synthesize the data using a hybrid thematic framework synthesis. This approach allows for a systematic link between our research questions and the evidence mapping by combining deductive and inductive coding. The process will follow the framework analysis method proposed by Ritchie and Spencer [<xref ref-type="bibr" rid="ref13">13</xref>] and the JBI methodological guidance for evidence synthesis [<xref ref-type="bibr" rid="ref14">14</xref>].</p><sec id="s2-6-1"><title>Deductive Coding</title><p>An initial framework will be established using categories derived from the study objectives, such as &#x201C;Theoretical Frameworks&#x201D; and &#x201C;SOC Scale Variations.&#x201D; These represent the &#x201C;expected themes&#x201D; identified in the pilot search.</p></sec><sec id="s2-6-2"><title>Inductive Refinement</title><p>Following the reflexive thematic analysis phases of Braun and Clarke [<xref ref-type="bibr" rid="ref15">15</xref>], reviewers will read the data to identify emerging codes that capture regional nuances, such as the transition from individual to collective resilience or the integration of <italic>Buen Vivir</italic> [<xref ref-type="bibr" rid="ref16">16</xref>].</p></sec><sec id="s2-6-3"><title>Mapping and Synthesis</title><p>The final narrative report will integrate numerical descriptions with these themes to provide a holistic view of the salutogenic paradigm in Mexico and Latin America.</p></sec></sec></sec><sec id="s3" sec-type="results"><title>Results</title><sec id="s3-1"><title>Project timeline</title><p>The project&#x2019;s timeline began with the conceptualization of the study in January 2025. This was followed by a preparatory phase from August to December 2025, which focused on protocol development and team training. The operational stages for 2026 commenced with database searches and duplicate removal in February and March, leading into the title and abstract screening in April. Looking ahead, the full-text review is projected for May and June, followed by data extraction and synthesis in July. The project is expected to conclude with the reporting phase, involving manuscript writing and submission, scheduled between August and December 2026.&#x201D;</p></sec><sec id="s3-2"><title>Preliminary Search Results</title><p>An initial pilot search in PubMed using the term &#x201C;Salutogenesis AND Mexico&#x201D; yielded 109 results, while &#x201C;Salutogenesis AND Latin America&#x201D; yielded 1150 results. This confirms the feasibility of the review but highlights the need for a trilingual search strategy to capture the full breadth of the literature. The protocol has been prepared following the PRISMA Extension for Scoping Reviews (PRISMA-ScR) checklist [<xref ref-type="bibr" rid="ref17">17</xref>] and the preliminary selection process is shown in <xref ref-type="fig" rid="figure1">Figure 1</xref>.</p><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>PRISMA diagram (PRISMA Extension for Scoping Reviews) [<xref ref-type="bibr" rid="ref18">18</xref>].</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="resprot_v15i1e83495_fig01.png"/></fig></sec></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Maturation of the Paradigm and the Global-Local Gap</title><p>This protocol represents a critical step in the maturation of health promotion research in Latin America [<xref ref-type="bibr" rid="ref19">19</xref>]. While salutogenesis has been extensively reviewed globally&#x2014;with a strong predominance of studies in Global North contexts&#x2014;the translation of this paradigm to Latin American socioeconomic and epidemiological realities remains fragmented. Foundational systematic reviews have mapped the impact of the SOC on specific health outcomes [<xref ref-type="bibr" rid="ref1">1</xref>]; however, there remains a persistent need for a comprehensive synthesis addressing how the model is operationalized in contexts of high structural inequality. By consolidating literature from regional databases such as LILACS and Redalyc, this study aims to bridge a critical gap, retrieving evidence that is often rendered invisible in Anglophone-centric reviews.</p></sec><sec id="s4-2"><title>Theoretical Implications: The Tension Between Individualism and Collectivism</title><p>We hypothesize that this review will reveal a fundamental epistemological tension between the individualistic genesis of the SOC construct and the inherently collectivistic nature of Latin American cultures. The protocol seeks to clarify whether the use of standard scales (SOC-29, SOC-13) has been uncritical or if there is a transition toward culturally adapted instruments that capture family and community resilience. This analysis is essential for theoretical development, as it allows for testing the universality of Antonovsky&#x2019;s constructs under regional worldviews such as <italic>Buen Vivir</italic> (Sumak Kawsay) [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>], suggesting that health in the Global South is not merely an individual psychological trait but a socio-ecological process of collective management.</p></sec><sec id="s4-3"><title>Implications for Practice and Public Policy</title><p>From a practical standpoint, the protocol is oriented toward transforming the traditional deficit-based model into an asset-based one. If the review confirms that a robust SOC is associated with better management of chronic conditions (such as diabetes in resource-limited settings), it will strengthen the argument for integrating salutogenic interventions into primary care [<xref ref-type="bibr" rid="ref22">22</xref>]. Specifically, the findings could support the implementation of &#x201C;social prescribing,&#x201D; connecting patients with community assets and support networks that bolster their comprehensibility, manageability, and meaningfulness. At a policy level, this study seeks to align with the PAHO Strategy and Plan of Action on Health Promotion 2019&#x2010;2030, providing evidence to shift from a &#x201C;war on disease&#x201D; toward governance that generates health through intersectoral interventions [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>].</p></sec><sec id="s4-4"><title>Design Strengths and Limitations</title><p>The main strength of this protocol lies in its trilingual search strategy and methodological rigor based on JBI and PRISMA-ScR guidelines. By including regional databases, representativeness is ensured, challenging global publication biases. However, it is acknowledged as a limitation that, as a scoping review, a formal assessment of the risk of bias of the included studies will not be conducted; instead, the priority will be an exhaustive mapping of the state of the art in the region.</p><p>The results will be disseminated through publication in a high-impact, peer-reviewed indexed journal. Additionally, we plan to create a brief for policymakers and present the findings at the Mexican Public Health Congress to ensure the translation of knowledge into local practice.</p></sec></sec><sec id="s5" sec-type="conclusions"><title>Conclusion</title><p>The transition toward a health system that truly promotes well-being requires solid theoretical foundations [<xref ref-type="bibr" rid="ref25">25</xref>]. This protocol establishes the roadmap to assess whether salutogenesis can be that foundation in Latin America [<xref ref-type="bibr" rid="ref26">26</xref>]. By mapping the existing evidence, it not only identifies academic gaps but also takes a step toward the decolonization of health knowledge, validating how our populations build health amidst adversity [<xref ref-type="bibr" rid="ref27">27</xref>].</p></sec></body><back><ack><p>Disclosure of Delegation to Generative AI: The authors declare the use of generative AI in the research and writing process. According to the GAIDeT taxonomy (2025), the following tasks were delegated to GAI tools under full human supervision:</p><p>- Translation</p><p>The GAI tool used was: GEMINI PRO. Responsibility for the final manuscript lies entirely with the authors. GAI tools are not listed as authors and do not bear responsibility for the final outcomes. Declaration submitted by: Rigoberto Antonio Cisneros Garcia and Igor Martin Ramos Herrera</p><p>Additional note: We used GEMINI PRO for the text translation. The translation was also validated by the authors.</p></ack><notes><sec><title>Funding</title><p>This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.</p></sec></notes><fn-group><fn fn-type="other"><label>Author note</label><p>Disclosure of Delegation to Generative AI: The authors declare the use of generative AI in the research and writing process. According to the GAIDeT taxonomy (2025), the following tasks were delegated to GAI tools under full human supervision:</p><p>- Translation</p><p>The GAI tool used was: GEMINI PRO. Responsibility for the final manuscript lies entirely with the authors. GAI tools are not listed as authors and do not bear responsibility for the final outcomes. Declaration submitted by: Rigoberto Antonio Cisneros Garcia and Igor Martin Ramos Herrera</p><p>Additional note: We used GEMINI PRO for the text translation. 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