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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">ResProt</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Res Protoc</journal-id>
      <journal-title>JMIR Research Protocols</journal-title>
      <issn pub-type="epub">1929-0748</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v14i1e76668</article-id>
      <article-id pub-id-type="pmid">41143459</article-id>
      <article-id pub-id-type="doi">10.2196/76668</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Protocol</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Protocol</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Impact of Connected Mental Health on the Work Environment of Mental Health Clinicians: Protocol for a Systematic Literature Review</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Schwartz</surname>
            <given-names>Amy</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Chigevenga</surname>
            <given-names>Rosemary</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Pankhurst</surname>
            <given-names>Christian</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Premanandan</surname>
            <given-names>Shweta</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Division of Computing Science</institution>
            <institution>Department of Information Technology</institution>
            <institution>Uppsala University</institution>
            <addr-line>Hus 10, Regementsvägen 10</addr-line>
            <addr-line>Uppsala, 751 05</addr-line>
            <country>Sweden</country>
            <phone>46 707689331</phone>
            <email>shweta.premanandan@it.uu.se</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-0732-7009</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Ouhbi</surname>
            <given-names>Sofia</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-7614-9731</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Stadin</surname>
            <given-names>Magdalena Ramstedt</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-8196-1289</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Blease</surname>
            <given-names>Charlotte</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3657-2476</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Cajander</surname>
            <given-names>Åsa</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-7472-2215</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Hägglund</surname>
            <given-names>Maria</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-6839-3651</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Division of Computing Science</institution>
        <institution>Department of Information Technology</institution>
        <institution>Uppsala University</institution>
        <addr-line>Uppsala</addr-line>
        <country>Sweden</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Vi3</institution>
        <institution>Department of Information Technology</institution>
        <institution>Uppsala University</institution>
        <addr-line>Uppsala</addr-line>
        <country>Sweden</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Participatory eHealth and Health Data Research Group</institution>
        <institution>Department of Women's and Children's Health</institution>
        <institution>Uppsala University</institution>
        <addr-line>Uppsala</addr-line>
        <country>Sweden</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Shweta Premanandan <email>shweta.premanandan@it.uu.se</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2025</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>27</day>
        <month>10</month>
        <year>2025</year>
      </pub-date>
      <volume>14</volume>
      <elocation-id>e76668</elocation-id>
      <history>
        <date date-type="received">
          <day>28</day>
          <month>4</month>
          <year>2025</year>
        </date>
        <date date-type="rev-request">
          <day>24</day>
          <month>8</month>
          <year>2025</year>
        </date>
        <date date-type="rev-recd">
          <day>29</day>
          <month>9</month>
          <year>2025</year>
        </date>
        <date date-type="accepted">
          <day>8</day>
          <month>10</month>
          <year>2025</year>
        </date>
      </history>
      <copyright-statement>©Shweta Premanandan, Sofia Ouhbi, Magdalena Ramstedt Stadin, Charlotte Blease, Åsa Cajander, Maria Hägglund. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 27.10.2025.</copyright-statement>
      <copyright-year>2025</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Research Protocols, is properly cited. The complete bibliographic information, a link to the original publication on https://www.researchprotocols.org, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.researchprotocols.org/2025/1/e76668" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Many mental health professionals face work-related stress due to high job demands, limited control, and inadequate institutional support. Connected mental health (CMH) technologies such as mobile apps and teletherapy platforms are increasingly being proposed as tools to alleviate these job demands. However, their actual influence on clinicians’ work environments—here understood as the organizational, social, and psychological conditions that shape their workload, job demands, autonomy, and overall well-being—remains underexplored. Existing reviews have primarily focused on traditional organizational interventions, leaving a critical gap in understanding how CMH technologies specifically influence the work environment of mental health clinicians.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This systematic literature review aims to identify and summarize knowledge about the impact of CMH on the work environment of mental health clinicians.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>A systematic literature review will be performed. The review follows PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and has been registered in PROSPERO on April 23, 2025. A comprehensive search strategy was developed using the population, intervention, comparison, and outcome (PICO) framework in collaboration with an academic librarian. Studies will be sourced from the PubMed, Scopus, IEEE Xplore, and ACM Digital Library databases. Inclusion criteria are limited to empirical studies involving mental health clinicians using CMH tools, where outcomes explicitly relate to the work environment (eg, job demands, workload, autonomy, stress, or well-being). Eligible studies must be published in English. Data extraction will include publication trends, study methods, and types of CMH technologies. Additionally, the extraction will capture the study results, including qualitative and quantitative findings, along with the measurement instruments used. Two reviewers will independently select articles for review and extract data. Conflicts will be discussed, and a third reviewer will be consulted if a consensus cannot be reached. Descriptive statistics and thematic analysis (via NVivo) will be used to synthesize the findings.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>This systematic literature review seeks to explore and synthesize existing research on how CMH technologies affect clinicians’ work environments and is expected to be completed by December 2025.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>This review will offer a comprehensive overview of how CMH technologies affect the professional work environment of clinicians.</p>
        </sec>
        <sec sec-type="trial registration">
          <title>Trial Registration</title>
          <p>PROSPERO CRD420251018685; https://www.crd.york.ac.uk/PROSPERO/view/CRD420251018685</p>
        </sec>
        <sec sec-type="registered-report">
          <title>International Registered Report Identifier (IRRID)</title>
          <p>PRR1-10.2196/76668</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>connected mental health</kwd>
        <kwd>work environment</kwd>
        <kwd>mental health clinicians</kwd>
        <kwd>digital mental health applications</kwd>
        <kwd>burnout</kwd>
        <kwd>systematic literature review</kwd>
        <kwd>artificial intelligence</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Overview</title>
        <p>The global rise in mental health conditions has placed significant pressure on health care systems, with an increasing number of individuals seeking support [<xref ref-type="bibr" rid="ref1">1</xref>]. Although not all individuals with the highest needs seek help due to factors such as stigma, cultural background, or socioeconomic status, those who do contribute to the growing demand for mental health care services [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref3">3</xref>]. This growing demand contributes to a heavier workload and greater responsibility for mental health professionals [<xref ref-type="bibr" rid="ref4">4</xref>]. Research across various countries has highlighted that professionals working in mental health care often face some of the most challenging working conditions [<xref ref-type="bibr" rid="ref5">5</xref>-<xref ref-type="bibr" rid="ref7">7</xref>]. These include high workloads, elevated stress levels, administrative burdens, staffing shortages, limited resources, exposure to violence, interpersonal conflicts, and role ambiguity. It is also important to acknowledge that many mental health care professionals themselves experience burnout and mental health conditions. However, concerns about stigma and professional repercussions often make them reluctant to seek support [<xref ref-type="bibr" rid="ref8">8</xref>]. Connected mental health (CMH) applications have been proposed as potential solutions to increase access to mental health care services and alleviate some of the pressures faced by mental health professionals [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>].</p>
        <p>CMH refers to the use of information and communication technologies in mental health care to overcome barriers such as stigma, education, and cost [<xref ref-type="bibr" rid="ref11">11</xref>]. It encompasses various technology-based solutions, including online platforms, mobile apps, and wearable devices, which can aid in diagnosing, managing, and treating common mental health issues [<xref ref-type="bibr" rid="ref12">12</xref>]. CMH has shown promise in assisting health care workers during the COVID-19 pandemic [<xref ref-type="bibr" rid="ref11">11</xref>] and in supporting the transition from primary to secondary school [<xref ref-type="bibr" rid="ref13">13</xref>]. Research indicates an increasing interest in CMH, with journals being the main publication channels and exploratory research dominating the field [<xref ref-type="bibr" rid="ref11">11</xref>]. Although attitudes toward CMH are generally positive, concerns exist regarding technical issues, the digital divide, and institutional barriers [<xref ref-type="bibr" rid="ref14">14</xref>].</p>
        <p>The work environment is a multidimensional concept encompassing physical, social, and organizational factors that influence employee satisfaction, performance, and well-being [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>]. It includes job demands, health management, work design, leadership, work-life balance, and recognition [<xref ref-type="bibr" rid="ref16">16</xref>,<xref ref-type="bibr" rid="ref17">17</xref>]. A positive work environment can improve organizational outcomes, reduce turnover, and increase engagement [<xref ref-type="bibr" rid="ref18">18</xref>]. The workplace environment significantly impacts employee morale, productivity, and quality of life [<xref ref-type="bibr" rid="ref19">19</xref>]. Organizations can enhance employee loyalty and well-being by improving working conditions and the overall environment [<xref ref-type="bibr" rid="ref20">20</xref>]. Managers must create an atmosphere that attracts, retains, and motivates employees in today’s diverse and changing work landscape [<xref ref-type="bibr" rid="ref18">18</xref>]. Digitalization has introduced both opportunities and challenges for the work environment, potentially enhancing efficiency and flexibility and increasing cognitive load, work intensification, and stress levels [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>]. Although the specific impact of CMH technologies on work environments remains underexplored, it is important to recognize that mental health care already operates under highly stressful and pressured conditions [<xref ref-type="bibr" rid="ref23">23</xref>]. Therefore, it is imperative to ensure that CMH implementations are designed to support and alleviate work-related stress rather than inadvertently contributing to additional strain on health care workers.</p>
        <p>Several systematic reviews have examined the impact of mental health systems and workplace environments on the well-being of clinicians [<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref26">26</xref>]. One major theme emerging from these reviews is the effectiveness of organizational-level interventions in reducing burnout and improving mental health among health care workers. A recent review emphasized that changes in job structure, work tasks, and physical environments are among the most effective strategies for supporting clinicians’ mental health [<xref ref-type="bibr" rid="ref24">24</xref>]. In contrast, reviews of workplace mental health screening programs have shown mixed results. For example, a systematic review and meta-analysis found that screening followed only by advice or referral did not significantly improve outcomes, whereas screening combined with access to treatment produced small improvements [<xref ref-type="bibr" rid="ref25">25</xref>]. Another review focusing on nurses in critical care settings found that the work environment was a significant contributor to high levels of depression and anxiety, pointing to the need for structural changes [<xref ref-type="bibr" rid="ref26">26</xref>].</p>
        <p>Although existing reviews provide valuable insights into the broader relationship between mental health systems and clinician well-being, they often focus on traditional organizational interventions, general workplace screening programs, or environmental stressors. However, there is a noticeable gap in synthesized knowledge specifically addressing how CMH technologies impact the work environment of mental health clinicians. The shift toward digital care has accelerated in recent years, particularly during and after the COVID-19 pandemic; however, the consequences for clinicians’ job demands, autonomy, workload, emotional labor, and professional identity remain fragmented across disciplines and underexplored in reviews. Moreover, although patient outcomes and accessibility are common focal points in CMH research, the clinician perspective, particularly in terms of occupational stress, job satisfaction, technology-induced strain, and ethical concerns, has not been systematically synthesized. This gap is especially critical given that mental health clinicians often manage emotionally intensive caseloads, and the integration of digital tools can both alleviate and exacerbate existing stressors.</p>
        <p>In addition to traditional organizational interventions, a growing body of research has explored the use of digital technologies to address employee mental health in workplace settings. Web-based stress management programs and computer-assisted interventions have demonstrated benefits in reducing stress and enhancing coping skills among employees [<xref ref-type="bibr" rid="ref27">27</xref>]. Workplace-delivered digital programs, including mobile apps for mindfulness, resilience, and psychological support, have been associated with improvements in well-being and reductions in anxiety and depression symptoms [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref29">29</xref>]. These studies suggest that technology-enabled interventions can be feasible and effective, but their adoption and sustained use often depend on usability, organizational readiness, and perceptions of confidentiality [<xref ref-type="bibr" rid="ref29">29</xref>]. Although these advances illustrate the potential of digital tools to improve workplace mental health, evidence remains fragmented, and no systematic review has specifically examined how CMH technologies influence the work environment of mental health clinicians.</p>
        <p>Therefore, this review aims to fill this critical gap by synthesizing the available evidence on the impact of CMH technologies on the work environment of mental health clinicians. It will offer insights into both the benefits and challenges of digital integration from a clinician-centered perspective, guiding technology design, policy, and workforce support in mental health services.</p>
      </sec>
      <sec>
        <title>Study Objectives</title>
        <p>The objective of the proposed systematic review is to synthesize and critically analyze the reported outcomes and impacts of CMH technologies on mental health clinicians’ work environments across diverse global contexts.</p>
      </sec>
      <sec>
        <title>Research Questions</title>
        <p>In the medical domain, the population, intervention, comparison, and outcome (PICO) framework is commonly used and recommended to develop research questions (RQs), especially for systematic literature reviews (<xref ref-type="boxed-text" rid="box1">Textbox 1</xref>) [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref31">31</xref>]. This ensures that only the studies most likely to be relevant will be retrieved and analyzed [<xref ref-type="bibr" rid="ref32">32</xref>]. Although the PICO framework primarily aims to structure search strategies, past studies have occasionally excluded certain PICO elements based on research requirements such as the comparison component [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>]. For this study, we also omit this component, as it is not suitable for the study. This is because we do not aim to rank the studies found or to compare them with some other existing approach.</p>
        <boxed-text id="box1" position="float">
          <title>Population, intervention, comparison, and outcome structure.</title>
          <list list-type="bullet">
            <list-item>
              <p>Population: studies that include mental health care professionals such as psychiatrists and psychologists</p>
            </list-item>
            <list-item>
              <p>Intervention: connected mental health applications</p>
            </list-item>
            <list-item>
              <p>Comparison: not applicable</p>
            </list-item>
            <list-item>
              <p>Outcome: the work environment of mental health care professionals such as psychiatrists and psychologists</p>
            </list-item>
          </list>
        </boxed-text>
        <p>The population to be included will be mental health care professionals such as psychiatrists and psychologists. The intervention will be CMH applications. The outcomes of interest will be work-related stress or other work environment factors.</p>
        <p>The following RQs guided this systematic literature review:</p>
        <list list-type="order">
          <list-item>
            <p>What are the positive and negative impacts of using CMH applications on mental health clinicians’ work environments?</p>
          </list-item>
          <list-item>
            <p>What technical challenges are associated with the impact of CMH applications on mental health clinicians’ work environments?</p>
          </list-item>
          <list-item>
            <p>Which design features of CMH applications enable their effectiveness in workplace settings for mental health clinicians?</p>
          </list-item>
        </list>
        <p>In addition, we will report on the characteristics of the identified publications, including temporal distribution, publication avenues, country of origin, types of studies conducted, and types of CMH applications studied.</p>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Study Design</title>
        <p>This systematic review was submitted for registration with PROSPERO on April 23, 2025 (CRD420251018685) to avoid bias in conducting and reporting findings. According to the progress of the study, amendments will be made if necessary. The PRISMA-P (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols) checklist [<xref ref-type="bibr" rid="ref35">35</xref>] is provided as <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p>
        <p>We selected a systematic literature review approach because our goal is to summarize the research related to the influence of CMH on the work environment and the barriers to adopting CMH, as well as to identify the types of mental health applications currently in use. Therefore, we followed widely recognized guidelines [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref31">31</xref>] to plan and conduct a systematic literature review. Database searches and screening were conducted between April and July 2025. Data extraction and analysis of the included studies are being performed between August and November 2025. The review manuscript is scheduled for submission in December 2025.</p>
      </sec>
      <sec>
        <title>Search Strategy</title>
        <p>This review will analyze studies that discuss mental health care professionals’ use of CMH applications and their impact on the work environment. The search strategy for this systematic literature review was developed in collaboration with Görel Sundström, a librarian at Uppsala University, and the research team (SP, SO, MH, CB, ÅC, and MRS). The PICO statement was used to construct the search strategy, as shown in <xref ref-type="table" rid="table1">Table 1</xref>.</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Search strategy.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="70"/>
            <col width="200"/>
            <col width="730"/>
            <thead>
              <tr valign="top">
                <td>Search</td>
                <td>Keyword group</td>
                <td>Search string</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>1</td>
                <td>Connected mental health</td>
                <td>TITLE-ABS-KEY (“e mental health” OR “m mental health” OR ((“psychological health” OR “mental health” OR psychotherapy OR “behavi* therapy”) W/2 (connected OR digital OR mobile OR online OR smart OR tele OR video OR web)))</td>
              </tr>
              <tr valign="top">
                <td>2</td>
                <td>Work environment</td>
                <td>TITLE-ABS-KEY (((job OR work*) W/2 (abuse* OR bullying OR condition* OR control* OR demand OR engagement OR environment* OR satisfaction OR stress* OR setting OR situation* OR strain OR violence OR well-being OR wellbeing)) OR “burn* out” OR burnout* OR “effort-reward imbalance” OR “employee* health” OR ergonomic* OR ERI OR “occupational health” OR “occupational safety” OR “occupational stress” OR “work life balance” OR “workplace health”)</td>
              </tr>
              <tr valign="top">
                <td>3</td>
                <td>Mental health professionals</td>
                <td>TITLE-ABS-KEY (clinician* OR counsellor or counselor OR doctor* OR “health personnel” OR “health professional*” OR “healthcare professional*” OR “healthcare provider*” OR “healthcare worker*” OR “health care professional*” OR “health care provider*” OR “health care worker*” OR “general practitioner” OR “medical staff” OR nurse* OR “nursing staff” OR physician* OR psychiatrist* OR psychoanalyst* OR psychologist* OR psychotherapist* OR therapist*)</td>
              </tr>
              <tr valign="top">
                <td>4</td>
                <td>Combined search</td>
                <td>1 AND 2 AND 3</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
        <p>The refinement of keywords involved multiple strategies: the librarian performed testing, and the team examined the cited articles to identify their keyword choices. The goal was to ensure that the search captured studies that addressed the same RQs using different terminologies.</p>
        <p>The search will be conducted across a range of electronic databases: PubMed, IEEE Xplore, Scopus, and ACM Digital Library. The selected databases are chosen for their relevance to the research topic and their broad use in academic and research settings. This systematic review will not involve the collection of sensitive personal data. The search for publications is completed.</p>
      </sec>
      <sec>
        <title>Study Selection Criteria</title>
        <p>The PICO statement was used to define the eligibility criteria for study inclusion and exclusion as shown in <xref ref-type="table" rid="table2">Table 2</xref>.</p>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Inclusion and exclusion criteria based on population, intervention, comparison, and outcome (PICO) framework.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="130"/>
            <col width="440"/>
            <col width="430"/>
            <thead>
              <tr valign="top">
                <td>PICO</td>
                <td>Inclusion criteria</td>
                <td>Exclusion criteria</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Population</td>
                <td>Mental health care professionals, physicians, and nurses, with no exclusion based on age or gender</td>
                <td>Study participants who are not mental health care professionals, physicians, or nurses</td>
              </tr>
              <tr valign="top">
                <td>Intervention</td>
                <td>Mental health applications (eg, self-guided CBT<sup>a</sup> apps, mood tracking, or AI<sup>b</sup>-driven chat support) and video consultations, which enable remote interaction between patients and mental health professionals.</td>
                <td>General health care applications</td>
              </tr>
              <tr valign="top">
                <td>Comparison</td>
                <td>Not applicable</td>
                <td>Not applicable</td>
              </tr>
              <tr valign="top">
                <td>Outcome</td>
                <td>Influence on the work environment</td>
                <td>Not applicable</td>
              </tr>
              <tr valign="top">
                <td>Study methods</td>
                <td>Qualitative methods, quantitative methods, mixed methods, solution proposal, evaluation research, and experience articles</td>
                <td>Reviews (systematic, scoping, meta-analysis, etc)</td>
              </tr>
              <tr valign="top">
                <td>Publication types</td>
                <td>Formally published peer-reviewed journal articles and conference articles</td>
                <td>Gray literature, opinion pieces, protocols, and reviews</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>CBT: cognitive behavioral therapy.</p>
            </fn>
            <fn id="table2fn2">
              <p><sup>b</sup>AI: artificial intelligence.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Types of Studies</title>
        <sec>
          <title>Qualitative Studies</title>
          <p>Qualitative studies include interviews, focus group discussions, usability studies, participatory research, participatory design, case studies, grounded theory research, thematic and content analysis of textual data, phenomenological studies, narrative research, and ethnographic observations.</p>
        </sec>
        <sec>
          <title>Quantitative Studies</title>
          <p>Quantitative studies include randomized controlled trials, cohort studies, longitudinal studies, experimental studies, case-control studies, cross-sectional studies, and observational studies.</p>
        </sec>
        <sec>
          <title>Mixed Methods Studies</title>
          <p>Mixed methods studies include those integrating qualitative and quantitative data collection and analysis methods within a single research design, encompassing, but not restricted to, convergent design, sequential explanatory design, and sequential exploratory design.</p>
        </sec>
      </sec>
      <sec>
        <title>Language</title>
        <p>Because of limited resources, this study will only consider articles published in English. The research team recognizes that this decision restricts the inclusion of studies conducted in various regions and published in other languages.</p>
      </sec>
      <sec>
        <title>Study Screening</title>
        <p>An independent librarian will first run a search using predefined keywords aligned with the inclusion and exclusion criteria to find potentially relevant studies. The search results will then be deduplicated by identifying and removing duplicates in EndNote (version 21; Clarivate), following the guidelines by Bramer et al [<xref ref-type="bibr" rid="ref36">36</xref>]. The remaining studies will then be imported to Rayyan [<xref ref-type="bibr" rid="ref37">37</xref>]. Data will first be screened on the title and abstract, and finally, on full-text screening. At least 2 reviewers will independently review the titles and abstracts during the first step. They will be blinded to each other’s review decision [<xref ref-type="bibr" rid="ref38">38</xref>]. Thereafter, the potential articles will be screened based on their full text. In case of disagreements between the reviewers, another reviewer will be consulted to reach a consensus.</p>
      </sec>
      <sec>
        <title>Data Extraction</title>
        <p>Data will be extracted using a standardized form developed by the research team. This form is structured to collect key study details, including (1) identification—study ID, authors, year, country, publication type, and study type (qualitative, quantitative, or mixed methods); (2) study characteristics—clinician demographics, age, sample size, and CMH application (digital platform or software used and delivery medium); and (3) results—findings in both qualitative and quantitative formats and the tools used for measurement.</p>
        <p>Additional details may be incorporated if the research team deems them relevant to the analysis. One reviewer will carry out the data extraction independently, and a second reviewer will review the extracted data to ensure accuracy and completeness. All extracted information will be compiled into a predesigned table in Microsoft Excel. In addition, qualitative data related to the results and findings will be collected. These qualitative data will subsequently be analyzed to identify important themes using NVivo (version 14; Lumivero).</p>
      </sec>
      <sec>
        <title>Quality Assessment and Appraisal in the Screening Process</title>
        <p>The quality of the included studies will be assessed using the Mixed Methods Appraisal Tool (MMAT) [<xref ref-type="bibr" rid="ref39">39</xref>], which is specifically designed for systematic reviews that include qualitative, quantitative, and mixed methods studies. As shown in previous systematic reviews, the MMAT is reliable and efficient [<xref ref-type="bibr" rid="ref40">40</xref>]. The assessment will be based on method-specific criteria, including the appropriateness and rigor of the methodology, control of confounding factors, minimization of selection bias, and consideration of study limitations. Two researchers will independently carry out the MMAT assessments and will reach a consensus on their evaluations. In cases of disagreement, a third researcher will be consulted.</p>
      </sec>
      <sec>
        <title>Data Analysis and Synthesis</title>
        <p>The study selection procedure will be illustrated using the PRISMA 2020 flow diagram, as demonstrated in <xref rid="figure1" ref-type="fig">Figure 1</xref> [<xref ref-type="bibr" rid="ref41">41</xref>]. Data synthesis will combine quantitative descriptive summaries with qualitative thematic analysis to ensure alignment with the RQs. These will be visualized through tables and charts in Microsoft Excel. Descriptive statistics will be used to address questions related to publication trends, study designs, contexts, and the types of CMH technologies investigated. This will involve frequency counts and distributions presented in tables and figures.</p>
        <p>To address RQ1, we will conduct thematic analysis following the 6-phase framework proposed by Braun and Clarke [<xref ref-type="bibr" rid="ref42">42</xref>]. Extracted data relating to work environment outcomes (eg, job demands, workload, autonomy, stress, and well-being) will be inductively coded. Codes will be collated into themes that represent how CMH technologies influence specific aspects of clinicians’ work environments. Themes will be reviewed and refined iteratively by multiple reviewers to ensure consistency, with NVivo software (version 14; Lumivero) used to support coding and transparency.</p>
        <p>For RQ2, we will extract data relating to technical barriers (eg, interoperability, usability, system reliability, and data security). These will be coded inductively and synthesized thematically, highlighting how technical challenges shape or constrain work environment outcomes.</p>
        <p>To answer RQ3, we will identify and code reported design features (eg, interface design, workflow integration, decision support, communication tools) and analyze them thematically. This synthesis will enable us to link specific design features to the reported positive or negative impacts in clinical work environments.</p>
        <p>In addition to thematic analysis, descriptive statistics will summarize bibliometric and study characteristics (eg, year of publication, country, study design, type of CMH technology). These will contextualize the thematic findings and help identify patterns and gaps across the literature. Together, the descriptive and thematic analyses will provide a systematic answer to all 3 RQs.</p>
        <p>One reviewer will conduct the coding, and a second reviewer will verify the sample for consistency. The findings will be synthesized narratively and supported by visual representations. The PRISMA 2020 flow diagram will illustrate the study selection process.</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flow diagram.</p>
          </caption>
          <graphic xlink:href="resprot_v14i1e76668_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Dissemination Strategy</title>
        <p>The results of this study will be disseminated as a scientific publication in a peer-reviewed journal and presented at conferences. Results will also be shared on the blogs of various research groups that the authors are a part of.</p>
      </sec>
      <sec>
        <title>Ethical Considerations</title>
        <p>According to the Ethical Review Act (2003:460) issued by the Swedish Ethical Review Authority, this research does not require ethics approval.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>The authors have conducted 2 pilot searches to test and refine keywords and verify the initial quality of results with the help of the librarian. We have identified 386 studies for screening. Database searches and screening were completed by July 2025. The review team is currently engaged in data extraction and thematic analysis of the included studies, a process scheduled to be concluded by November 2025. The completed systematic review will be submitted for publication in December 2025.</p>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Anticipated Findings</title>
        <p>This systematic review investigates how CMH applications influence the work environment of mental health clinicians. Although the results are pending, this review is expected to highlight the key trends, tools, outcomes, and challenges in this emerging field. We anticipate identifying a steady rise in publications, signaling a growing interest in CMH among researchers. Commonly studied technologies will likely include mobile apps and teletherapy platforms. Expected outcomes include positive effects such as reduced stress, improved mental well-being, and enhanced support for clinicians. However, the review also aims to uncover challenges such as poor usability, concerns over data privacy, digital fatigue, and limited institutional support, factors that may hinder adoption or long-term use. By focusing on clinicians, this review shifts attention from patient-centered outcomes to the well-being and work conditions of those delivering care. The findings will provide practical insights for developers, health care organizations, and policymakers seeking to implement CMH tools that genuinely support clinicians and, in turn, their patients, rather than compounding their burdens.</p>
      </sec>
      <sec>
        <title>Comparison to Previous Work</title>
        <p>Previous reviews on digital workplace mental health programs have shown benefits for employee well-being, although adoption is shaped by usability and organizational readiness [<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref29">29</xref>]. In contrast, our review focuses on clinicians as workers, examining how CMH tools used in patient care affect their own job demands and resources. Research on telemental health highlights implementation barriers, confidentiality, and increased electronic health record workload [<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref44">44</xref>], while technostress studies describe how system complexity and poor support reduce well-being [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]. Our synthesis will connect these strands to clinicians’ work environments using the job demands–resources framework [<xref ref-type="bibr" rid="ref46">46</xref>].</p>
      </sec>
      <sec>
        <title>Expected Contributions</title>
        <p>This review is expected to make several contributions. First, it will provide a clinician-centered synthesis of how CMH applications influence work environment factors such as workload, autonomy, collaboration, and well-being—areas that are often overshadowed by patient-focused outcomes in the literature. Second, it will identify the design features and technical challenges most consistently associated with positive or negative impacts, offering insights into how these technologies can be optimized for clinical settings. Finally, by linking these findings to the job demands–resources framework, this review will generate practical guidance for both technology design and organizational implementation, thereby informing future development, policy, and research.</p>
      </sec>
      <sec>
        <title>Strengths, Limitations, and Future Directions</title>
        <p>A significant strength of this review is that the protocol has been prospectively registered, which enhances transparency and reduces the risk of selective reporting. The review also follows PRISMA guidelines, ensuring methodological rigor in searching, screening, and reporting. Another strength is the use of 3 reviewers in screening and data extraction, which minimizes bias and increases reliability in study selection and coding. In addition, the combination of descriptive synthesis with thematic analysis provides both breadth—through mapping publication trends and study characteristics—and depth—through an interpretive account of how CMH technologies shape clinicians’ work environments. At the same time, several limitations of this study must be acknowledged. The included studies are likely to be heterogeneous in design, outcomes, and contexts, which may complicate the synthesis and limit comparability. Some studies may not include formal comparators, making it difficult to directly attribute changes to CMH technologies. Restricting the review to English-language studies also introduces the possibility of language bias, potentially excluding relevant work from non-English or gray literature sources. To mitigate these limitations, we will use transparent coding procedures, map outcomes consistently to the job demands–resources framework to enhance comparability and explicitly acknowledge contextual and methodological gaps in the evidence base.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>This protocol outlines a systematic literature review that will evaluate and synthesize evidence on the impacts of CMH technologies on the work environments of mental health clinicians. By systematically analyzing both positive and negative outcomes, technical challenges, and enabling design features, this review will provide an understanding of how CMH applications shape clinicians’ job demands, resources, and well-being. The use of a PRISMA-guided methodology, combined with descriptive and thematic synthesis, and alignment with the job demands–resources framework, supports the development of findings that will be robust and practically relevant. The anticipated contribution of this review is twofold: advancing the academic literature by clarifying the state of evidence in this area and informing technology developers, health care organizations, and policymakers seeking to design and implement CMH solutions that are sustainable and supportive of clinicians’ work environments. Ultimately, the results are expected to generate insights that can guide future research, design, and policy, while also identifying critical gaps, particularly in underrepresented regions, that warrant further investigation.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>PRISMA-P checklist.</p>
        <media xlink:href="resprot_v14i1e76668_app1.docx" xlink:title="DOCX File , 18 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">CMH</term>
          <def>
            <p>connected mental health</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">MMAT</term>
          <def>
            <p>Mixed Methods Appraisal Tool</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">PICO</term>
          <def>
            <p>population, intervention, comparison, and outcome</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">PRISMA-P</term>
          <def>
            <p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">RQ</term>
          <def>
            <p>research question</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The authors would like to thank Uppsala University librarian Görel Sundström for assisting with the search strategy. This research is funded by Forskningsrådet för hälsa, arbetsliv och välfärd (FORTE; STY-2024/0004). The funders had no role in the study design, protocol preparation, decision to publish, or preparation of the manuscript.</p>
    </ack>
    <notes>
      <sec>
        <title>Data Availability</title>
        <p>Data sharing is not applicable to this study as no datasets were generated or analyzed during this study.</p>
      </sec>
    </notes>
    <fn-group>
      <fn fn-type="con">
        <p>SP, SO, and MH contributed to the conception. SP wrote the initial manuscript draft. The manuscript has been revised by SP, SO, MH, CB, ÅC, and MRS. Visualization was performed by SP. All authors reviewed and edited the manuscript and approved the final version of the manuscript.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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