<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "http://dtd.nlm.nih.gov/publishing/2.0/journalpublishing.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">ResProt</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Res Protoc</journal-id>
      <journal-title>JMIR Research Protocols</journal-title>
      <issn pub-type="epub">1929-0748</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
    <article-id pub-id-type="publisher-id">v5i4e231</article-id>
    <article-id pub-id-type="pmid">27956377</article-id>
    <article-id pub-id-type="doi">10.2196/resprot.6285</article-id>
    <article-categories>
      <subj-group subj-group-type="heading">
        <subject>Protocol</subject>
      </subj-group>
      <subj-group subj-group-type="article-type">
        <subject>Protocol</subject>
      </subj-group>
    </article-categories>
    <title-group>
      <article-title>Examining Incentives to Promote Physical Activity Maintenance Among Hospital Employees Not Achieving 10,000 Daily Steps: A Web-Based Randomized Controlled Trial Protocol</article-title>
    </title-group>
    <contrib-group>
      <contrib contrib-type="editor">
        <name>
          <surname>Eysenbach</surname>
          <given-names>Gunther</given-names>
        </name>
      </contrib>
    </contrib-group>
    <contrib-group>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Kramer</surname>
          <given-names>Jan-Niklas</given-names>
        </name>
      </contrib>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Ploderer</surname>
          <given-names>Bernd</given-names>
        </name>
      </contrib>
    </contrib-group>
    <contrib-group>
      <contrib contrib-type="author" id="contrib1" corresp="yes">
      <name name-style="western">
        <surname>Mitchell</surname>
        <given-names>Marc</given-names>
      </name>
      <degrees>PhD</degrees>
      <xref rid="aff1" ref-type="aff">1</xref>
      <address>
        <institution>Toronto Rehabilitation Institute</institution>
        <institution>University Health Network</institution>
        <addr-line>347 Rumsey Rd</addr-line>
        <addr-line>Toronto, ON</addr-line>
        <country>Canada</country>
        <phone>1 416 660 7781</phone>
        <fax>1 416 425 0301</fax>
        <email>marc.mitchell@uhn.ca</email>
      </address>  
      <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-2772-9614</ext-link></contrib>
      <contrib contrib-type="author" id="contrib2">
        <name name-style="western">
          <surname>White</surname>
          <given-names>Lauren</given-names>
        </name>
        <degrees>MSc</degrees>
        <xref rid="aff2" ref-type="aff">2</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-9935-3732</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib3">
        <name name-style="western">
          <surname>Oh</surname>
          <given-names>Paul</given-names>
        </name>
        <degrees>MSc, MD</degrees>
        <xref rid="aff1" ref-type="aff">1</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-0603-6958</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib4">
        <name name-style="western">
          <surname>Kwan</surname>
          <given-names>Matthew</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff3" ref-type="aff">3</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-9757-2771</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib5">
        <name name-style="western">
          <surname>Gove</surname>
          <given-names>Peter</given-names>
        </name>
        <degrees>MSW</degrees>
        <xref rid="aff4" ref-type="aff">4</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0003-0383-8039</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib6">
        <name name-style="western">
          <surname>Leahey</surname>
          <given-names>Tricia</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff5" ref-type="aff">5</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-8134-3838</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib7">
        <name name-style="western">
          <surname>Faulkner</surname>
          <given-names>Guy</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff6" ref-type="aff">6</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-8898-2536</ext-link>
      </contrib>
    </contrib-group>
    <aff id="aff1">
    <sup>1</sup>
    <institution>Toronto Rehabilitation Institute</institution>
    <institution>University Health Network</institution>  
    <addr-line>Toronto, ON</addr-line>
    <country>Canada</country></aff>
    <aff id="aff2">
    <sup>2</sup>
    <institution>Faculty of Kinesiology and Physical Education</institution>
    <institution>University of Toronto</institution>  
    <addr-line>Toronto, ON</addr-line>
    <country>Canada</country></aff>
    <aff id="aff3">
    <sup>3</sup>
    <institution>Department of Family Medicine</institution>
    <institution>McMaster University</institution>  
    <addr-line>Hamilton, ON</addr-line>
    <country>Canada</country></aff>
    <aff id="aff4">
      <sup>4</sup>
      <institution>Green Shield Canada Inc</institution>
      <addr-line>Toronto, ON</addr-line>
      <country>Canada</country>
    </aff>
    <aff id="aff5">
      <sup>5</sup>
      <institution>University of Connecticut</institution>
      <addr-line>Storrs, CT</addr-line>
      <country>United States</country>
    </aff>
    <aff id="aff6">
    <sup>6</sup>
    <institution>School of Kinesiology</institution>
    <institution>University of British Columbia</institution>  
    <addr-line>Vancouver, BC</addr-line>
    <country>Canada</country></aff>
    <author-notes>
      <corresp>Corresponding Author: Marc Mitchell 
      <email>marc.mitchell@uhn.ca</email></corresp>
    </author-notes>
    <pub-date pub-type="collection"><season>Oct-Dec</season><year>2016</year></pub-date>
    <pub-date pub-type="epub">
      <day>12</day>
      <month>12</month>
      <year>2016</year>
    </pub-date>
    <volume>5</volume>
    <issue>4</issue>
    <elocation-id>e231</elocation-id>
    <!--history from ojs - api-xml-->
    <history>
      <date date-type="received">
        <day>28</day>
        <month>6</month>
        <year>2016</year>
      </date>
      <date date-type="rev-request">
        <day>29</day>
        <month>7</month>
        <year>2016</year>
      </date>
      <date date-type="rev-recd">
        <day>13</day>
        <month>10</month>
        <year>2016</year>
      </date>
      <date date-type="accepted">
        <day>22</day>
        <month>10</month>
        <year>2016</year>
      </date>
    </history>
    <!--(c) the authors - correct author names and publication date here if necessary. Date in form ', dd.mm.yyyy' after jmir.org-->
    <copyright-statement>©Marc Mitchell, Lauren White, Paul Oh, Matthew Kwan, Peter Gove, Tricia Leahey, Guy Faulkner. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 12.12.2016.</copyright-statement>
    <copyright-year>2016</copyright-year>
    <license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0/">
      <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Research Protocols, is properly cited. The complete bibliographic information, a link to the original publication on http://www.researchprotocols.org, as well as this copyright and license information must be included.</p>
    </license>  
    <self-uri xlink:href="http://www.researchprotocols.org/2016/4/e231/" xlink:type="simple"/>
    <abstract>
      <sec sec-type="background">
        <title>Background</title>
        <p>The economic burden of physical inactivity in Canada is estimated at Can $6.8 billion (US $5 billion) per year. Employers bear a substantial proportion of the economic costs, as they pay more for inactive workers in health care and other organizational costs. In response, many Canadian employers offer wellness programs, though these are often underutilized. While financial health incentives have been proposed as one way of increasing participation, their longer term effects (ie postintervention effects) are not clear.</p>
      </sec>
      <sec sec-type="objective">
        <title>Objective</title>
        <p>The objective of this paper is to outline the methodology for a randomized control trial (RCT) examining the longer term impact of an existing physical activity promotion program that is enhanced by adding guaranteed rewards (Can $1 [US $0.74] per day step goal met) in a lower active hospital employee population (less than 10,000 steps per day).</p>
      </sec>
      <sec sec-type="methods">
        <title>Methods</title>
        <p>A 12-week, parallel-arm RCT (with a 12-week postintervention follow-up) will be employed. Employees using Change4Life (a fully automated, incentive-based wellness program) and accumulating fewer than 10,000 steps per day at baseline (weeks 1 to 2) will be randomly allocated (1:1) to standard care (wellness program, accelerometer) or an intervention group (standard care plus guaranteed incentives). All study participants will be asked to wear the accelerometer and synchronize it to Change4Life daily, although only intervention group participants will receive guaranteed incentives for reaching tailored daily step count goals (Can $1 [US $0.74] per day; weeks 3 to 12). The primary study outcome will be mean proportion of participant-days step goal reached during the postintervention follow-up period (week 24). Mean proportion of participant-days step goal reached during the intervention period (week 12) will be a secondary outcome.</p>
      </sec>
      <sec sec-type="results">
        <title>Results</title>
        <p>Enrollment for the study will be completed in February 2017. Data analysis will commence in September 2017. Study results are to be published in the winter of 2018.</p>
      </sec>
      <sec sec-type="conclusions">
        <title>Conclusions</title>
        <p>This protocol was designed to examine the impact of guaranteed rewards on physical activity maintenance in lower active hospital employees.</p>
      </sec>
      <sec sec-type="clinicalTrial">
        <title>ClinicalTrial</title>
        <p>ClinicalTrials.gov NCT02638675; https://clinicaltrials.gov/ct2/show/NCT0 2638675 (Archived by WebCite at http://www.webcitation.org/6g4pvZvhW)</p>
      </sec>
    </abstract>
    <kwd-group>
      <kwd>financial health incentives</kwd>
      <kwd>physical activity</kwd>
      <kwd>behavioral economics</kwd>
      <kwd>randomized controlled trial</kwd>
      <kwd>workplace health</kwd>
    </kwd-group></article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>There is a substantial economic burden associated with physical inactivity in Canada [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref2">2</xref>]. According to Janssen [<xref ref-type="bibr" rid="ref1">1</xref>], the cost of inactivity is Can $6.8 billion (US $5.0 billion) per year, posing a significant threat to the sustainability of the Canadian health care system. On the other hand, the projected cost savings of increasing the proportion of Canadians who meet physical activity guidelines (ie, 150 minutes of moderate-vigorous physical activity [MVPA] per week, or roughly 10,000 steps per day) by just 1% is Can $2.1 billion (US $1.6 billion) per year [<xref ref-type="bibr" rid="ref3">3</xref>]. Notably, significant reductions in health risk and associated costs and improvements in quality of life are seen when inactive (&#60;5000 steps per day) and low active (5000 to 7499 steps per day) adults become a little more active (eg, 1000 more steps per day) [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref4">4</xref>]. The workplace is an ideal setting for physical activity promotion since Canadian jobs are increasingly desk-based and sedentary [<xref ref-type="bibr" rid="ref5">5</xref>].</p>
      <p>Not surprisingly, Canadian employers bear a significant proportion of the inactivity burden because they pay more for lower active (&#60;10,000 steps per day) workers in health care expenses [<xref ref-type="bibr" rid="ref6">6</xref>]. For instance, while Canadian provincial and territorial governments cover hospital- and physician-related medical costs, employers in Canada often subsidize other medical expenses, one of the costliest being chronic disease–related medications [<xref ref-type="bibr" rid="ref6">6</xref>]. A study by Wang and colleagues [<xref ref-type="bibr" rid="ref7">7</xref>] helps to illustrate the economic benefit of a more physically active employee population. This study found that moderately active (1 to 2 times per week) and very active (3 or more times per week) employees had Can $250 (US $185) less paid health care costs annually when compared to their sedentary counterparts (0 times per week). In addition, wellness initiatives that increase employees’ physical activity have been shown to reduce absenteeism, presenteeism, and turnover [<xref ref-type="bibr" rid="ref8">8</xref>-<xref ref-type="bibr" rid="ref11">11</xref>]. Finally, according to health care surveys by Towers Watson [<xref ref-type="bibr" rid="ref12">12</xref>] and Sanofi [<xref ref-type="bibr" rid="ref6">6</xref>], Canadian employers have a vested interest in employees’ physical activity levels given the positive effects on organizational costs (eg, health care expenses) and performance (eg, presenteeism).</p>
      <p>As a result, the majority (72%) of large Canadian companies now offer wellness programs to help reduce overall health care spending and increase productivity [<xref ref-type="bibr" rid="ref6">6</xref>]. For participating employees, such programs have been associated with a reduced risk of chronic illness and lower medical claim costs [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref14">14</xref>]. However, these programs are chronically underutilized. In Canada, wellness program participation rates are extremely low, less than 10% [<xref ref-type="bibr" rid="ref6">6</xref>]. This means that more than 90% of eligible Canadian workers are not reaping the benefits of company-sponsored wellness programming. Behavioral economics, a new branch of economics that is complemented by insights from psychology, has stimulated renewed interest in financial health incentives as a means to increase wellness program participation [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref15">15</xref>-<xref ref-type="bibr" rid="ref17">17</xref>].</p>
      <p>Behavioral economics recognizes that human decisions are biased in systematic ways and that that these “decision biases” can be leveraged to facilitate healthy decision making [<xref ref-type="bibr" rid="ref18">18</xref>]. For example, according to behavioral economics, increasing the immediately rewarding aspects of a healthy behavior (eg, with a financial incentive) may offset the so-called “present bias” where people tend to overweigh the immediate costs (and discount the future benefits) of those behaviors (eg, time out of a busy schedule to exercise) [<xref ref-type="bibr" rid="ref19">19</xref>]. Systematic reviews by Mitchell et al [<xref ref-type="bibr" rid="ref20">20</xref>] and Strohacker et al [<xref ref-type="bibr" rid="ref21">21</xref>] support the theory suggesting that incentives generally stimulate physical activity in the short-term (less than 3 months) and while incentives are in place. These reviews also suggest that not enough studies have examined the longer term (ie, postintervention) impact of incentives on physical activity to draw conclusions about sustained effects [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>]—an issue of particular interest to Canadian employers looking to deliver cost-effective incentive-based wellness programs [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref6">6</xref>].</p>
      <p>Of the randomized controlled trials (RCTs) that have recently examined this issue [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref26">26</xref>], 4 have observed a regression to baseline behaviors after incentive removal [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref26">26</xref>] and only 1 has demonstrated persisting physical activity [<xref ref-type="bibr" rid="ref25">25</xref>]. One reason for this may have to do with the limited application of health behavior change theories in the design of incentive programs [<xref ref-type="bibr" rid="ref19">19</xref>]. It is increasingly suggested that for incentives to both stimulate and sustain health behavior change they should be grounded in theory [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]. In the single “positive” study, behavioral maintenance (ie, 16-week follow-up) was driven entirely by the lower active subgroup (ie, university students visiting the gym fewer than once per week at baseline)—possibly because exposure to the new behavior (ie, gym attendance) led to increased confidence to perform that behavior [<xref ref-type="bibr" rid="ref25">25</xref>]. This presumption aligns well with self-determination theory, a global theory of motivation focused on the extent to which behaviors are done volitionally, which suggests that incentive programs designed to increase a person’s confidence are more likely to foster self-determined (or intrinsic) motivation [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>]—a key driver of sustained physical activity [<xref ref-type="bibr" rid="ref30">30</xref>].</p>
      <p>Realizing the potential of incentives to promote sustained physical activity, therefore, will be contingent on research that improves the understanding of theoretical (eg, self-determined motivation) and contextual (eg, target group characteristics) factors that may influence incentive program effectiveness. The purpose of this protocol is to outline the design of an RCT that will examine the longer term effects of an existing physical activity promotion program that is enhanced by guaranteed incentives for lower active employees only in a real-world, ecological setting. We hypothesize that targeting lower active employees with incentives for tailored daily step goals (in addition to the generic, one-size-fits-all approach to goal setting that is typically used) may be more likely to create mastery experiences, increase confidence, and promote physical activity maintenance.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Study Design</title>
        <p>A 12-week, parallel-arm RCT with a 12-week postintervention follow-up will be employed to examine the impact of an enhanced (Can $1 [US $0.74] per day) incentive program on objectively measured physical activity among lower active employees (&#60;10,000 steps per day) within a large Canadian hospital network. See the study flow chart in <xref ref-type="fig" rid="figure1">Figure 1</xref>, including an overview of the enrollment process and assessments.</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>Study flowchart.</p>
          </caption>
          <graphic xlink:href="resprot_v5i4e231_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Study Population and Recruitment</title>
        <p>This study will specifically target lower active employees (&#60;10,000 steps per day). Hospital employees (including health care professionals and administrative and business support personnel) enrolled in the Change4Life program will be invited to participate via website notifications and hospital newsletters. Only data from participants who accumulate less than 10,000 steps per day during the “2-Week Run-In” period will be included in the analysis. Further eligibility criteria will include: 18 years of age or older, English speaking, ready Internet access, and without medical conditions exacerbated by physical activity as assessed by the Physical Activity Readiness Questionnaire Plus. Eligible participants will be asked to provide their expressed consent using the online consent form.</p>
      </sec>
      <sec>
        <title>Change4Life</title>
        <p>Change4Life, a Web- and incentive-based health education and behavior change program, was launched in May 2015 at the hospital network. The hospital network is offering Change4Life to 6500 full-time employees across 8 worksites. Specifically, the Web-based wellness program offers educational information relating to chronic disease prevention via learning modules (ie, series of short articles and quizzes). All employees who sign up for Change4Life are rewarded with points for completing these modules as well as for setting health-related goals, self-reporting health behaviors/outcomes, identifying barriers, and creating action plans—self-regulatory behaviors that have been theorized and empirically proven to promote sustained health behavior change (see the Change4Life Steps Study calendar in <xref ref-type="fig" rid="figure2">Figure 2</xref>) [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>]. Using points, employees may “purchase” ballots in the Change4Life reward store and enter into drawings for health-promoting products (eg, groceries, exercise equipment). At the hospital network, Change4Life operates as a minimal chance-based incentive program (low frequency, low magnitude rewards), where participants have less than a 1 in 100 chance of winning reward drawings that generally range in value from Can $5 to $20 (US $3.70-$14.80).</p>
        <fig id="figure2" position="float">
          <label>Figure 2</label>
          <caption>
            <p>Change4Life Steps Study calendar (ie, tracking page).</p>
          </caption>
          <graphic xlink:href="resprot_v5i4e231_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Standard Care Group</title>
        <p>Standard care group participants will have access to Change4Life and will receive the standard minimal chance-based incentives (ie, less than 1 in 100 chance of earning Can $5 to $20 [US $3.70-$14.80] vouchers) for completing learning modules and health tasks. In addition, standard care participants will be asked to wear the accelerometer, which tracks steps and 10-minute bouts of MVPA per day, synchronize the device to the Change4Life program daily, and reach tailored daily step count goals for 10 weeks (weeks 3 to 12). Standard care participants will be instructed to increase their daily step counts by 1000 steps above their baseline average every 2 weeks until they reach the target goal of 3000 extra steps at week 7 (see <xref ref-type="table" rid="table1">Table 1</xref>). Change4Life will automatically calculate the average baseline value in the early hours of day 1, week 3 using data uploaded the previous 2 weeks (the Run-In period)—days with step counts less than 100 or greater than 50,000 will not be included in calculations [<xref ref-type="bibr" rid="ref31">31</xref>]. This tailored and graded approach to setting step goals is more realistic than the traditional 10,000 step target (ie, the average Canadian adults accumulates only about 5000 steps per day) [<xref ref-type="bibr" rid="ref32">32</xref>], may increase chances of intervention success (versus offering a lofty 10,000 step per day goal for everyone), and has worked well in employee populations in the past [<xref ref-type="bibr" rid="ref33">33</xref>].</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Daily step count goals across the Change4Life program.</p>
          </caption>
          <table width="481" cellpadding="7" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="102"/>
            <col width="348"/>
            <thead>
              <tr valign="top">
                <td>Study week</td>
                <td>Step count goal</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Weeks 1-2</td>
                <td>2-Week Run-In (to confirm lower active status and calculate daily step count average)</td>
              </tr>
              <tr valign="top">
                <td>Weeks 3-4</td>
                <td>Increase daily steps by 1000 above baseline average</td>
              </tr>
              <tr valign="top">
                <td>Weeks 5-6</td>
                <td>Increase daily steps by 2000 above baseline average</td>
              </tr>
              <tr valign="top">
                <td>Weeks 7-8</td>
                <td>Increase daily steps by 3000 above baseline average</td>
              </tr>
              <tr valign="top">
                <td>Weeks 9-12</td>
                <td>Maintain steps at 3000 above baseline average</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
      </sec>
      <sec>
        <title>Intervention Group</title>
        <p>The only difference between the standard care and intervention groups will be the addition of the guaranteed incentive (Can $1 [US $0.74] per day). During the intervention period (weeks 3 to 12), intervention group participants will be eligible to earn Can $1 (US $0.74) in vouchers (eg, groceries, coffee, or movies) each time tailored daily step goals are achieved. The total amount available over the intervention period will be Can $70 (US $51.82). Previous research suggests that as little as Can $6.75 (US $5) per week may be sufficient to produce favorable lifestyle health behavior changes [<xref ref-type="bibr" rid="ref34">34</xref>], thus Can $7 (US $5.18) per week (Can $1 [US $0.74] per day) was chosen as the size of the incentive. During the study follow-up period (weeks 13 to 24), intervention participants will no longer receive the per day reward for reaching daily step goals.</p>
      </sec>
      <sec>
        <title>Outcome Measures</title>
        <p>The primary study outcome will be the mean proportion of participant-days that step goals are achieved during week 24 (the postintervention follow-up assessment period, T3). Mean proportion of participant-days that step goals are achieved during week 12 (intervention end point, T2) and volume of steps and 10-minute bouts of MVPA per week at T2 and T3 will be secondary outcomes. Physical activity will be objectively assessed using the StepsCount Piezo Rx accelerometer (StepsCount Inc, Deep River, ON, Canada). The Piezo Rx is a medical-grade device with a single axis piezoelectric sensor. This device has been found to be valid in calculating step counts and MVPA among adult participants [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>]. Standard care and intervention participants will be encouraged to wear their accelerometer and synchronize it to the Change4Life program during the baseline 2-Week Run-In period (T1), as well as at the intervention end point (T2), and follow-up assessment (T3) with Can $10 (US $7.40) study retention vouchers; these vouchers for assessment completion will help minimize dropout and will not be contingent on step goal achievement.</p>
        <p>The adherence outcome variables will be mean number of missing step count entries per week as well as mean number of Change4Life website log-ins in general. Participants’ self-determined motivation to exercise will be examined using the Behavioral Regulation to Exercise Questionnaire-3 (BREQ-3) [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref38">38</xref>]. Participants’ walking self-efficacy will be assessed using a modified version of the Self-Efficacy for Exercise Scale (SEE Scale) [<xref ref-type="bibr" rid="ref39">39</xref>]. The BREQ-3 and the SEE Scale will be administered online at baseline (T1), intervention end point (T2), and during the follow-up assessment period (T3). The differential impact of the Can $1 (US $0.74) per day incentive on the various physical activity outcomes will be explored. For instance, we may find that while the guaranteed incentives stimulate step goal achievement at T2, they also undermine self-determined motivation and thus the prospect that people will continue to exercise after the incentive is removed.</p>
      </sec>
      <sec>
        <title>Sample Size</title>
        <p>Sample size calculations indicate that a final sample of 158 participants (79 per group) ensures 80% power (<italic>P</italic>&#60;.05; 2-tailed) to detect a 0.20 difference in the mean proportion of participant-days step goals are reached between intervention and standard care groups for week 24 [<xref ref-type="bibr" rid="ref24">24</xref>]. This calculation assumes that the mean proportion of participant-days step goal achieved in the intervention group in week 24 will be 0.40 (vs 0.20 in the standard care group) [<xref ref-type="bibr" rid="ref24">24</xref>]. On the basis of data published by Patel et al [<xref ref-type="bibr" rid="ref22">22</xref>] this difference translates into a relative effect size of 0.40. The participant enrollment target will be increased to 174 to account for a potential 10% dropout rate, a rate that has been reported by other similar studies [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref26">26</xref>].</p>
      </sec>
      <sec>
        <title>Randomization and Blinding</title>
        <p>Employees accumulating fewer than 10,000 steps per day during the baseline period (study weeks 1 and 2) will be randomized using a single, constant allocation ratio (1:1) to standard care or intervention groups. Randomization will occur using an online random number generator [<xref ref-type="bibr" rid="ref40">40</xref>]. Participants will not be blinded to study group allocation. The research analysts will be blinded to group allocation until after the study is completed.</p>
      </sec>
      <sec>
        <title>Statistical Analyses</title>
        <p>For each participant on each day of the study (participant-day level) continuous step count data will be obtained and screened for outliers (less than 100 steps per day, more than 50,000 steps per day) [<xref ref-type="bibr" rid="ref31">31</xref>]. If participants did not synchronize their accelerometer for at least 3 separate workdays at T2 and T3, the last observation will be carried forward using T1 or T2 means [<xref ref-type="bibr" rid="ref33">33</xref>]. This procedure conservatively assumes no change in variables and allows analysis by intention-to-treat. The step count data will then be dichotomized at the participant-day level to create a binary variable where participants achieved (value = 1) or did not achieve (value = 0) their step goal. Using this binary variable, the mean proportion of participant-days where step goals were achieved at week 24 will be compared.</p>
        <p>SPSS version 21.0 (IBM Corp) will be used to fit a generalized linear model with participant random effects, a random intercept, time-fixed effects (T1-T3), and treatment-fixed effects (by study group). A binomial distribution with logit link for models using the binary outcome will be used to estimate the adjusted difference in the proportion of participant-days step goal achieved, and the bootstrap procedure and resampling of participants will be used to obtain 95% confidence intervals and <italic>P</italic> values. Comparisons across study groups will be adjusted for mean steps per day (baseline), age, gender, and income since these have moderated incentive-effects in the past [<xref ref-type="bibr" rid="ref41">41</xref>]. The same procedures will be used to analyze T2 (ie, intervention end) binary data.</p>
        <p>For continuous step count (ie, mean steps per day) and bout minutes (ie, total minutes of MVPA in 10-minute bouts per week) data at T2 and T3, a generalized linear model will be used, as above, except the difference in steps per day and MVPA bout minutes between groups will be obtained using least-squares means. Also, a repeated measures analysis of variance using linear mixed models with first order autoregressive covariance structures will be used to compare changes in self-determined motivation and self-efficacy between groups. Adherence will be analyzed using <italic>t</italic> tests comparing the mean number of missing step count entries per week and mean number of website log-ins per month between groups. This protocol is registered with ClinicalTrials.gov [NCT02638675].</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>Enrollment for the study will be completed in February 2017. Data analysis will commence in September 2017. Study results are to be published in the winter of 2018.</p>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Overview</title>
        <p>Physical activity maintenance is critical for controlling the human and economic burden of chronic disease [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref2">2</xref>]. While incentives have stimulated physical activity behaviors in the past [<xref ref-type="bibr" rid="ref20">20</xref>-<xref ref-type="bibr" rid="ref26">26</xref>], only 1 RCT to our knowledge has produced longer term, postintervention improvements [<xref ref-type="bibr" rid="ref25">25</xref>]. The primary aim of this protocol is to outline the design of an RCT to test whether adding theoretically informed guaranteed incentives to an existing physical activity promotion program can drive physical activity for 12 weeks after guaranteed incentives are removed in a workplace context. Since one of the risks with incentives is that they damage self-determined motivation and thus people’s potential for sustained change [<xref ref-type="bibr" rid="ref42">42</xref>], the theoretical considerations in this study extend beyond behavioral economics (which merely describes how incentives may be used as a catalyst for change) [<xref ref-type="bibr" rid="ref19">19</xref>] to include insights from self-determination theory (which describes the conditions under which incentives may produce sustained change) [<xref ref-type="bibr" rid="ref29">29</xref>]. The literature examining the undermining effect of incentives has mostly considered simple tasks for which initial intrinsic motivation is high, although these findings should not be generalized to lifestyle health behaviors like physical activity where initial intrinsic motivation can be low [<xref ref-type="bibr" rid="ref43">43</xref>]. In addition, incentive schemes vary greatly in their design and can differentially moderate the undermining effect [<xref ref-type="bibr" rid="ref43">43</xref>]. While more research is needed, schemes that target less active adults for realistic behavioral outcomes are theorized to support the internalization process and promote quality behavior change [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>].</p>
        <p>According to self-determination theory, incentives may help to build self-determined motivation primarily through their action on self-efficacy, especially for lower active people who exhibit fewer intrinsic motives to begin with (less motivation to crowd out) [<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]. Regarding physical activity, one hypothesis is that incentives may increase a person’s self-efficacy to become more active by exposing them to a form of physical activity for the first time [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]. Especially if the activity is an achievable one (eg, walk 1000 more steps per day vs walk 10,000 steps per day), individuals may find their confidence to be more active increases after just a few weeks [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]. To align with self-determination theory, then, we decided to (1) target lower active employees only (because they have less/little self-determined motivation to crowd out) [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref29">29</xref>] and (2) offer incentives contingent on tailored/realistic step goal achievements (to maximize mastery experiences and increase self-efficacy) [<xref ref-type="bibr" rid="ref45">45</xref>]. The main theoretical contribution of this protocol therefore is in its application of self-determination theory to the design of the incentive intervention (ie, realistic behavioral targets) and program evaluation (ie, tracking motivation throughout).</p>
        <p>The practical implications of this research are also important given the growing popularity of incentive-based wellness programs [<xref ref-type="bibr" rid="ref42">42</xref>]. First of all, we hope the results of this RCT encourage others to incorporate a simple but important incentive program design nuance by offering rewards contingent on tailored, rather than generic, physical activity goals. The pervasiveness of wearable physical activity monitors in general (eg, smartphones with built-in accelerometers) may make it easier for interventionists or employers to individualize physical activity goals in the context of a health rewards system (by setting goals based on an individual’s own physical activity pattern). Another practical implication of this study may be in encouraging employers to consider guaranteed rewards systems for higher-risk, higher-cost employees only versus the traditional (and largely ineffective) approach of offering low-frequency, low-magnitude chance-based rewards to everyone. To manage budgets, employers often opt for the seemingly more affordable chance-based reward scheme even though there is limited evidence of its effectiveness [<xref ref-type="bibr" rid="ref20">20</xref>]. Finally, if incentives are not amenable to employees, the intervention will almost certainly fail [<xref ref-type="bibr" rid="ref46">46</xref>]. Employers deploying incentives should therefore consider any unintended consequences of this novel approach, including (1) perceived unfairness (eg, Why should only lower active employees be rewarded to exercise?), (2) opportunity cost concerns (eg, Should we really be spending money on this?), (3) gaming/cheating (eg, I will cheat by getting my friend to track my activity for me), and (4) low overall acceptability (eg, I don’t want my employer telling me what to do) [<xref ref-type="bibr" rid="ref47">47</xref>-<xref ref-type="bibr" rid="ref49">49</xref>]. One way of circumventing the perceived unfairness issue may be in offering minimal chance-based rewards to all employees regardless of physical activity level as well as an enhanced incentive program to employees qualifying as lower active or higher-risk. Supporting such an approach with empirical data may alleviate concerns around unfairness, opportunity cost, and acceptability as well [<xref ref-type="bibr" rid="ref47">47</xref>-<xref ref-type="bibr" rid="ref49">49</xref>].</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>This study protocol is not without limitations. First, given that only employees already enrolled in Change4Life (less than 10% of the eligible employee population) will be assessed for eligibility and invited to participate in the study, the results may not be generalizable. By recruiting only lower active Change4Life enrollees, we will learn more about how a higher risk employee population responds to incentives. Since the hallmark of Web-based health interventions is low engagement [<xref ref-type="bibr" rid="ref49">49</xref>], there is potential for significant study dropout as well (ceasing daily device synchronization and not participating in assessments), especially among standard care participants. Both intervention and standard care participants will be encouraged to participate in all scheduled assessments (baseline, intervention end point, follow-up) with Can $10 (US $7.40) vouchers. Given the low participant burden and potential for lower active individuals to experience improved health, however, this voluntary incentive-based wellness program may be met with relatively high levels of engagement. Finally, participants will not be blinded to study group allocation, which could contaminate the results. Knowledge of group allocation will be assessed using a study exit survey to monitor this potential confounder.</p>
      </sec>
      <sec>
        <title>Conclusion</title>
        <p>The objective of this study is to improve the longer term maintenance of physical activity through a better understanding of how to structure and evaluate incentive programs. Incentives are not a panacea, of course, and may not work for all people, but as part of broader package of interventions and under certain conditions incentives may have a role to play in driving sustained health behavior change.</p>
      </sec>
    </sec>
  </body>
  <back>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">BREQ-3</term>
          <def>
            <p>Behavioral Regulation to Exercize Questionnaire</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">MVPA</term>
          <def>
            <p>moderate-vigorous physical activity</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">SEE</term>
          <def>
            <p>Self-Efficacy for Exercise</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The authors gratefully acknowledge Green Shield Canada Inc, the sponsor of this paper and the trial described within. The sponsor reviewed and approved this manuscript.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>Dr Marc Mitchell reports grant support from the Canadian Institutes of Health Research and the University Health Network as well as in-kind research support from Cookson James Loyalty Inc. Further, he is president of the financial health incentive consulting company Incentive Avenue Inc and reports consulting income from Carrot Insights Inc and stock options in Carrot Insights Inc.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Janssen</surname>
            <given-names>I</given-names>
          </name>
        </person-group>
        <article-title>Health care costs of physical inactivity in Canadian adults</article-title>
        <source>Appl Physiol Nutr Metab</source>  
        <year>2012</year>  
        <month>08</month>  
        <volume>37</volume>  
        <issue>4</issue>  
        <fpage>803</fpage>  
        <lpage>806</lpage>  
        <pub-id pub-id-type="doi">10.1139/h2012-061</pub-id>
        <pub-id pub-id-type="medline">22667697</pub-id></nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Li</surname>
            <given-names>L</given-names>
          </name>
        </person-group>
        <article-title>The financial burden of physical inactivity</article-title>
        <source>J Sport Health Science</source>  
        <year>2014</year>  
        <month>03</month>  
        <volume>3</volume>  
        <issue>1</issue>  
        <fpage>58</fpage>  
        <lpage>59</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.jshs.2013.12.003</pub-id></nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Krueger</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Turner</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Krueger</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Ready</surname>
            <given-names>AE</given-names>
          </name>
        </person-group>
        <article-title>The economic benefits of risk factor reduction in Canada: tobacco smoking, excess weight and physical inactivity</article-title>
        <source>Can J Public Health</source>  
        <year>2014</year>  
        <volume>105</volume>  
        <issue>1</issue>  
        <fpage>e69</fpage>  
        <lpage>e78</lpage>  
        <pub-id pub-id-type="medline">24735700</pub-id></nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Garber</surname>
            <given-names>CE</given-names>
          </name>
          <name name-style="western">
            <surname>Blissmer</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Deschenes</surname>
            <given-names>MR</given-names>
          </name>
          <name name-style="western">
            <surname>Franklin</surname>
            <given-names>BA</given-names>
          </name>
          <name name-style="western">
            <surname>Lamonte</surname>
            <given-names>MJ</given-names>
          </name>
          <name name-style="western">
            <surname>Lee</surname>
            <given-names>I</given-names>
          </name>
          <name name-style="western">
            <surname>Nieman</surname>
            <given-names>DC</given-names>
          </name>
          <name name-style="western">
            <surname>Swain</surname>
            <given-names>DP</given-names>
          </name>
          <collab>American College of Sports Medicine</collab>
        </person-group>
        <article-title>American College of Sports Medicine position stand: quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise</article-title>
        <source>Med Sci Sports Exerc</source>  
        <year>2011</year>  
        <month>07</month>  
        <volume>43</volume>  
        <issue>7</issue>  
        <fpage>1334</fpage>  
        <lpage>1359</lpage>  
        <pub-id pub-id-type="doi">10.1249/MSS.0b013e318213fefb</pub-id>
        <pub-id pub-id-type="medline">21694556</pub-id>
        <pub-id pub-id-type="pii">00005768-201107000-00026</pub-id></nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <collab>Conference Board of Canada</collab>
        </person-group>
        <source>Moving Ahead: Workplace Interventions to Reduce Physical Inactivity and Sedentary Behaviour</source>  
        <year>2015</year>  
        <access-date>2016-11-10</access-date>
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://sportmatters.ca/sites/default/files/content/moving_ahead_-workplace_behaviour_pub9271_br.pdf">http://sportmatters.ca/sites/default/files/content/moving_ahead_-workplace_behaviour_pub9271_br.pdf</ext-link>
          <ext-link ext-link-type="webcite" xlink:href="6g50P4KMk"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="web">
        <source>The Sanofi Canada Healthcare Survey 2015</source>  

        <access-date>2016-11-21</access-date>
        <comment>Benefits 2020: Shifting gears toward health management. 2015. 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.sanofi.ca/l/ca/en/download.jsp?file=4E103D9D-8AC6-4965-9D4E-6D0D5E7A8400.pdf">http://www.sanofi.ca/l/ca/en/download.jsp?file=4E103D9D-8AC6-4965-9D4E-6D0D5E7A8400.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6g4zRzzlb"/></comment> </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Wang</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>McDonald</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Champagne</surname>
            <given-names>LJ</given-names>
          </name>
          <name name-style="western">
            <surname>Edington</surname>
            <given-names>DW</given-names>
          </name>
        </person-group>
        <article-title>Relationship of body mass index and physical activity to health care costs among employees</article-title>
        <source>J Occup Environ Med</source>  
        <year>2004</year>  
        <month>05</month>  
        <volume>46</volume>  
        <issue>5</issue>  
        <fpage>428</fpage>  
        <lpage>436</lpage>  
        <pub-id pub-id-type="medline">15167389</pub-id>
        <pub-id pub-id-type="pii">00043764-200405000-00005</pub-id></nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>van Dongen</surname>
            <given-names>JM</given-names>
          </name>
          <name name-style="western">
            <surname>Proper</surname>
            <given-names>KI</given-names>
          </name>
          <name name-style="western">
            <surname>van Wier</surname>
            <given-names>MF</given-names>
          </name>
          <name name-style="western">
            <surname>van der Beek</surname>
            <given-names>AJ</given-names>
          </name>
          <name name-style="western">
            <surname>Bongers</surname>
            <given-names>PM</given-names>
          </name>
          <name name-style="western">
            <surname>van Mechelen</surname>
            <given-names>W</given-names>
          </name>
          <name name-style="western">
            <surname>van Tulder</surname>
            <given-names>MW</given-names>
          </name>
        </person-group>
        <article-title>Systematic review on the financial return of worksite health promotion programmes aimed at improving nutrition and/or increasing physical activity</article-title>
        <source>Obes Rev</source>  
        <year>2011</year>  
        <month>12</month>  
        <volume>12</volume>  
        <issue>12</issue>  
        <fpage>1031</fpage>  
        <lpage>1049</lpage>  
        <pub-id pub-id-type="doi">10.1111/j.1467-789X.2011.00925.x</pub-id>
        <pub-id pub-id-type="medline">21883870</pub-id></nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Hutchinson</surname>
            <given-names>AD</given-names>
          </name>
          <name name-style="western">
            <surname>Wilson</surname>
            <given-names>C</given-names>
          </name>
        </person-group>
        <article-title>Improving nutrition and physical activity in the workplace: a meta-analysis of intervention studies</article-title>
        <source>Health Promot Int</source>  
        <year>2012</year>  
        <month>06</month>  
        <volume>27</volume>  
        <issue>2</issue>  
        <fpage>238</fpage>  
        <lpage>249</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://heapro.oxfordjournals.org/cgi/pmidlookup?view=long&#38;pmid=21733915"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1093/heapro/dar035</pub-id>
        <pub-id pub-id-type="medline">21733915</pub-id>
        <pub-id pub-id-type="pii">dar035</pub-id></nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Meenan</surname>
            <given-names>RT</given-names>
          </name>
          <name name-style="western">
            <surname>Vogt</surname>
            <given-names>TM</given-names>
          </name>
          <name name-style="western">
            <surname>Williams</surname>
            <given-names>AE</given-names>
          </name>
          <name name-style="western">
            <surname>Stevens</surname>
            <given-names>VJ</given-names>
          </name>
          <name name-style="western">
            <surname>Albright</surname>
            <given-names>CL</given-names>
          </name>
          <name name-style="western">
            <surname>Nigg</surname>
            <given-names>C</given-names>
          </name>
        </person-group>
        <article-title>Economic evaluation of a worksite obesity prevention and intervention trial among hotel workers in Hawaii</article-title>
        <source>J Occup Environ Med</source>  
        <year>2010</year>  
        <month>01</month>  
        <volume>52 Suppl 1</volume>  
        <fpage>S8</fpage>  
        <lpage>S13</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/20061889"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1097/JOM.0b013e3181c81af9</pub-id>
        <pub-id pub-id-type="medline">20061889</pub-id>
        <pub-id pub-id-type="pii">00043764-201001001-00003</pub-id>
        <pub-id pub-id-type="pmcid">PMC2821094</pub-id></nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Brown</surname>
            <given-names>HE</given-names>
          </name>
          <name name-style="western">
            <surname>Ryde</surname>
            <given-names>GC</given-names>
          </name>
          <name name-style="western">
            <surname>Gilson</surname>
            <given-names>ND</given-names>
          </name>
          <name name-style="western">
            <surname>Burton</surname>
            <given-names>NW</given-names>
          </name>
          <name name-style="western">
            <surname>Brown</surname>
            <given-names>WJ</given-names>
          </name>
        </person-group>
        <article-title>Objectively measured sedentary behavior and physical activity in office employees: relationships with presenteeism</article-title>
        <source>J Occup Environ Med</source>  
        <year>2013</year>  
        <month>08</month>  
        <volume>55</volume>  
        <issue>8</issue>  
        <fpage>945</fpage>  
        <lpage>953</lpage>  
        <pub-id pub-id-type="doi">10.1097/JOM.0b013e31829178bf</pub-id>
        <pub-id pub-id-type="medline">23887700</pub-id></nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <collab>Towers Watson</collab>
        </person-group>
        <source>2013/2014 Staying@Work Report: Canada Summary</source>  
        <year>2013</year>  
        <access-date>2016-03-17</access-date>
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.towerswatson.com/en-CA/Insights/IC-Types/Survey-Research-Results/2014/02/2013-2014-staying-at-work-report-canada-summary">https://www.towerswatson.com/en-CA/Insights/IC-Types/Survey-Research-Results/2014/02/2013-2014-staying-at-work-report-canada-summary</ext-link>
          <ext-link ext-link-type="webcite" xlink:href="6g50DKW7l"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Berry</surname>
            <given-names>LL</given-names>
          </name>
          <name name-style="western">
            <surname>Mirabito</surname>
            <given-names>AM</given-names>
          </name>
          <name name-style="western">
            <surname>Baun</surname>
            <given-names>WB</given-names>
          </name>
        </person-group>
        <article-title>What's the hard return on employee wellness programs?</article-title>
        <source>Harv Bus Rev</source>  
        <year>2010</year>  
        <month>12</month>  
        <volume>88</volume>  
        <issue>12</issue>  
        <fpage>104</fpage>  
        <lpage>112</lpage>  
        <pub-id pub-id-type="medline">21188899</pub-id></nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Henke</surname>
            <given-names>RM</given-names>
          </name>
          <name name-style="western">
            <surname>Goetzel</surname>
            <given-names>RZ</given-names>
          </name>
          <name name-style="western">
            <surname>McHugh</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Isaac</surname>
            <given-names>F</given-names>
          </name>
        </person-group>
        <article-title>Recent experience in health promotion at Johnson &#38; Johnson: lower health spending, strong return on investment</article-title>
        <source>Health Aff (Millwood)</source>  
        <year>2011</year>  
        <month>03</month>  
        <volume>30</volume>  
        <issue>3</issue>  
        <fpage>490</fpage>  
        <lpage>499</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://content.healthaffairs.org/cgi/pmidlookup?view=long&#38;pmid=21383368"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1377/hlthaff.2010.0806</pub-id>
        <pub-id pub-id-type="medline">21383368</pub-id>
        <pub-id pub-id-type="pii">30/3/490</pub-id></nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Stock</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Schmidt</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Büscher</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Gerber</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Drabik</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Graf</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Lüngen</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Stollenwerk</surname>
            <given-names>B</given-names>
          </name>
        </person-group>
        <article-title>Financial incentives in the German Statutory Health Insurance: new findings, new questions</article-title>
        <source>Health Policy</source>  
        <year>2010</year>  
        <month>06</month>  
        <volume>96</volume>  
        <issue>1</issue>  
        <fpage>51</fpage>  
        <lpage>56</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.healthpol.2009.12.015</pub-id>
        <pub-id pub-id-type="medline">20106543</pub-id>
        <pub-id pub-id-type="pii">S0168-8510(10)00007-2</pub-id></nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Ries</surname>
            <given-names>N</given-names>
          </name>
        </person-group>
        <article-title>Financial incentives for weight loss and healthy behaviours</article-title>
        <source>Healthc Policy</source>  
        <year>2012</year>  
        <month>02</month>  
        <volume>7</volume>  
        <issue>3</issue>  
        <fpage>23</fpage>  
        <lpage>28</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/23372578"/>
        </comment>  
        <pub-id pub-id-type="medline">23372578</pub-id>
        <pub-id pub-id-type="pmcid">PMC3298019</pub-id></nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Schmidt</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Stock</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Doran</surname>
            <given-names>T</given-names>
          </name>
        </person-group>
        <article-title>Issues in international health policy: moving forward with wellness incentives under the Affordable Care Act</article-title>
        <source>Issue Brief (Commonwealth Fund)</source>  
        <year>2012</year>  
        <fpage>1</fpage>  
        <lpage>12</lpage> </nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="book">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Camerer</surname>
            <given-names>CF</given-names>
          </name>
          <name name-style="western">
            <surname>Loewenstein</surname>
            <given-names>G</given-names>
          </name>
        </person-group>
        <person-group person-group-type="editor">
          <name name-style="western">
            <surname>Camerer</surname>
            <given-names>CF</given-names>
          </name>
          <name name-style="western">
            <surname>Loewenstein</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Rabin</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Behavioral economics: past, present, future</article-title>
        <source>Advances in Behavioral Economics</source>  
        <year>2003</year>  
        <publisher-loc>Princeton, NJ</publisher-loc>
        <publisher-name>Princeton University Press</publisher-name></nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Loewenstein</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Asch</surname>
            <given-names>DA</given-names>
          </name>
          <name name-style="western">
            <surname>Volpp</surname>
            <given-names>KG</given-names>
          </name>
        </person-group>
        <article-title>Behavioral economics holds potential to deliver better results for patients, insurers, and employers</article-title>
        <source>Health Aff (Millwood)</source>  
        <year>2013</year>  
        <month>07</month>  
        <volume>32</volume>  
        <issue>7</issue>  
        <fpage>1244</fpage>  
        <lpage>1250</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://content.healthaffairs.org/cgi/pmidlookup?view=long&#38;pmid=23836740"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1377/hlthaff.2012.1163</pub-id>
        <pub-id pub-id-type="medline">23836740</pub-id>
        <pub-id pub-id-type="pii">32/7/1244</pub-id></nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Mitchell</surname>
            <given-names>MS</given-names>
          </name>
          <name name-style="western">
            <surname>Goodman</surname>
            <given-names>JM</given-names>
          </name>
          <name name-style="western">
            <surname>Alter</surname>
            <given-names>DA</given-names>
          </name>
          <name name-style="western">
            <surname>John</surname>
            <given-names>LK</given-names>
          </name>
          <name name-style="western">
            <surname>Oh</surname>
            <given-names>PI</given-names>
          </name>
          <name name-style="western">
            <surname>Pakosh</surname>
            <given-names>MT</given-names>
          </name>
          <name name-style="western">
            <surname>Faulkner</surname>
            <given-names>GE</given-names>
          </name>
        </person-group>
        <article-title>Financial incentives for exercise adherence in adults: systematic review and meta-analysis</article-title>
        <source>Am J Prev Med</source>  
        <year>2013</year>  
        <month>11</month>  
        <volume>45</volume>  
        <issue>5</issue>  
        <fpage>658</fpage>  
        <lpage>667</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.amepre.2013.06.017</pub-id>
        <pub-id pub-id-type="medline">24139781</pub-id>
        <pub-id pub-id-type="pii">S0749-3797(13)00436-4</pub-id></nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Strohacker</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Galarraga</surname>
            <given-names>O</given-names>
          </name>
          <name name-style="western">
            <surname>Williams</surname>
            <given-names>DM</given-names>
          </name>
        </person-group>
        <article-title>The impact of incentives on exercise behavior: a systematic review of randomized controlled trials</article-title>
        <source>Ann Behav Med</source>  
        <year>2014</year>  
        <month>08</month>  
        <volume>48</volume>  
        <issue>1</issue>  
        <fpage>92</fpage>  
        <lpage>99</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/24307474"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1007/s12160-013-9577-4</pub-id>
        <pub-id pub-id-type="medline">24307474</pub-id>
        <pub-id pub-id-type="pmcid">PMC4412849</pub-id></nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Patel</surname>
            <given-names>MS</given-names>
          </name>
          <name name-style="western">
            <surname>Asch</surname>
            <given-names>DA</given-names>
          </name>
          <name name-style="western">
            <surname>Rosin</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Small</surname>
            <given-names>DS</given-names>
          </name>
          <name name-style="western">
            <surname>Bellamy</surname>
            <given-names>SL</given-names>
          </name>
          <name name-style="western">
            <surname>Heuer</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Sproat</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Hyson</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Haff</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Lee</surname>
            <given-names>SM</given-names>
          </name>
          <name name-style="western">
            <surname>Wesby</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Hoffer</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Shuttleworth</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Taylor</surname>
            <given-names>DH</given-names>
          </name>
          <name name-style="western">
            <surname>Hilbert</surname>
            <given-names>V</given-names>
          </name>
          <name name-style="western">
            <surname>Zhu</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Yang</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Wang</surname>
            <given-names>X</given-names>
          </name>
          <name name-style="western">
            <surname>Volpp</surname>
            <given-names>KG</given-names>
          </name>
        </person-group>
        <article-title>Framing financial incentives to increase physical activity among overweight and obese adults: a randomized, controlled trial</article-title>
        <source>Ann Intern Med</source>  
        <year>2016</year>  
        <month>03</month>  
        <day>15</day>  
        <volume>164</volume>  
        <issue>6</issue>  
        <fpage>385</fpage>  
        <lpage>394</lpage>  
        <pub-id pub-id-type="doi">10.7326/M15-1635</pub-id>
        <pub-id pub-id-type="medline">26881417</pub-id>
        <pub-id pub-id-type="pii">2491916</pub-id></nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Pope</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Harvey</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>The impact of incentives on intrinsic and extrinsic motives for fitness-center attendance in college first-year students</article-title>
        <source>Am J Health Promot</source>  
        <year>2015</year>  
        <volume>29</volume>  
        <issue>3</issue>  
        <fpage>192</fpage>  
        <lpage>199</lpage>  
        <pub-id pub-id-type="doi">10.4278/ajhp.140408-QUAN-135</pub-id>
        <pub-id pub-id-type="medline">25559252</pub-id></nlm-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Kullgren</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Troxel</surname>
            <given-names>AB</given-names>
          </name>
          <name name-style="western">
            <surname>Loewenstein</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Asch</surname>
            <given-names>DA</given-names>
          </name>
          <name name-style="western">
            <surname>Norton</surname>
            <given-names>LA</given-names>
          </name>
          <name name-style="western">
            <surname>Wesby</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Tao</surname>
            <given-names>Y</given-names>
          </name>
          <name name-style="western">
            <surname>Zhu</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Volpp</surname>
            <given-names>KG</given-names>
          </name>
        </person-group>
        <article-title>Individual- versus group-based financial incentives for weight loss: a randomized, controlled trial</article-title>
        <source>Ann Intern Med</source>  
        <year>2013</year>  
        <month>04</month>  
        <day>2</day>  
        <volume>158</volume>  
        <issue>7</issue>  
        <fpage>505</fpage>  
        <lpage>514</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/23546562"/>
        </comment>  
        <pub-id pub-id-type="doi">10.7326/0003-4819-158-7-201304020-00002</pub-id>
        <pub-id pub-id-type="medline">23546562</pub-id>
        <pub-id pub-id-type="pii">1671710</pub-id>
        <pub-id pub-id-type="pmcid">PMC3994977</pub-id></nlm-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Charness</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Gneezy</surname>
            <given-names>U</given-names>
          </name>
        </person-group>
        <article-title>Incentives to Exercise</article-title>
        <source>Econometrica</source>  
        <year>2009</year>  
        <volume>77</volume>  
        <issue>3</issue>  
        <fpage>909</fpage>  
        <lpage>931</lpage> </nlm-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Finkelstein</surname>
            <given-names>EA</given-names>
          </name>
          <name name-style="western">
            <surname>Haaland</surname>
            <given-names>BA</given-names>
          </name>
          <name name-style="western">
            <surname>Bilger</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Sahasranaman</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Sloan</surname>
            <given-names>RA</given-names>
          </name>
          <name name-style="western">
            <surname>Nang</surname>
            <given-names>EEK</given-names>
          </name>
          <name name-style="western">
            <surname>Evenson</surname>
            <given-names>KR</given-names>
          </name>
        </person-group>
        <article-title>Effectiveness of activity trackers with and without incentives to increase physical activity (TRIPPA): a randomised controlled trial</article-title>
        <source>Lancet Diabetes Endocrinol</source>  
        <year>2016</year>  
        <month>10</month>  
        <day>3</day>  
        <pub-id pub-id-type="doi">10.1016/S2213-8587(16)30284-4</pub-id>
        <pub-id pub-id-type="medline">27717766</pub-id>
        <pub-id pub-id-type="pii">S2213-8587(16)30284-4</pub-id></nlm-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Burns</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Donovan</surname>
            <given-names>AS</given-names>
          </name>
          <name name-style="western">
            <surname>Ackermann</surname>
            <given-names>RT</given-names>
          </name>
          <name name-style="western">
            <surname>Finch</surname>
            <given-names>EA</given-names>
          </name>
          <name name-style="western">
            <surname>Rothman</surname>
            <given-names>AJ</given-names>
          </name>
          <name name-style="western">
            <surname>Jeffery</surname>
            <given-names>RW</given-names>
          </name>
        </person-group>
        <article-title>A theoretically grounded systematic review of material incentives for weight loss: implications for interventions</article-title>
        <source>Ann Behav Med</source>  
        <year>2012</year>  
        <month>12</month>  
        <volume>44</volume>  
        <issue>3</issue>  
        <fpage>375</fpage>  
        <lpage>388</lpage>  
        <pub-id pub-id-type="doi">10.1007/s12160-012-9403-4</pub-id>
        <pub-id pub-id-type="medline">22907712</pub-id></nlm-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Oliver</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>A nudge too far? A nudge at all? On paying people to be healthy</article-title>
        <source>Healthc Pap</source>  
        <year>2012</year>  
        <volume>12</volume>  
        <issue>4</issue>  
        <fpage>8</fpage>  
        <lpage>16</lpage>  
        <pub-id pub-id-type="medline">23713394</pub-id></nlm-citation>
      </ref>
      <ref id="ref29">
        <label>29</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Deci</surname>
            <given-names>EL</given-names>
          </name>
          <name name-style="western">
            <surname>Koestner</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Ryan</surname>
            <given-names>RM</given-names>
          </name>
        </person-group>
        <article-title>A meta-analytic review of experiments examining the effects of extrinsic rewards on intrinsic motivation</article-title>
        <source>Psychol Bull</source>  
        <year>1999</year>  
        <month>11</month>  
        <volume>125</volume>  
        <issue>6</issue>  
        <fpage>627</fpage>  
        <lpage>668</lpage>  
        <pub-id pub-id-type="medline">10589297</pub-id></nlm-citation>
      </ref>
      <ref id="ref30">
        <label>30</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Teixeira</surname>
            <given-names>PJ</given-names>
          </name>
          <name name-style="western">
            <surname>Carraça</surname>
            <given-names>EV</given-names>
          </name>
          <name name-style="western">
            <surname>Markland</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Silva</surname>
            <given-names>MN</given-names>
          </name>
          <name name-style="western">
            <surname>Ryan</surname>
            <given-names>RM</given-names>
          </name>
        </person-group>
        <article-title>Exercise, physical activity, and self-determination theory: a systematic review</article-title>
        <source>Int J Behav Nutr Phys Act</source>  
        <year>2012</year>  
        <volume>9</volume>  
        <fpage>78</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://ijbnpa.biomedcentral.com/articles/10.1186/1479-5868-9-78"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1186/1479-5868-9-78</pub-id>
        <pub-id pub-id-type="medline">22726453</pub-id>
        <pub-id pub-id-type="pii">1479-5868-9-78</pub-id>
        <pub-id pub-id-type="pmcid">PMC3441783</pub-id></nlm-citation>
      </ref>
      <ref id="ref31">
        <label>31</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Bassett</surname>
            <given-names>JD</given-names>
          </name>
          <name name-style="western">
            <surname>Wyatt</surname>
            <given-names>HR</given-names>
          </name>
          <name name-style="western">
            <surname>Thompson</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Peters</surname>
            <given-names>JC</given-names>
          </name>
          <name name-style="western">
            <surname>Hill</surname>
            <given-names>JO</given-names>
          </name>
        </person-group>
        <article-title>Pedometer-measured physical activity and health behaviors in U.S. adults</article-title>
        <source>Med Sci Sports Exerc</source>  
        <year>2010</year>  
        <month>10</month>  
        <volume>42</volume>  
        <issue>10</issue>  
        <fpage>1819</fpage>  
        <lpage>1825</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/20305579"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1249/MSS.0b013e3181dc2e54</pub-id>
        <pub-id pub-id-type="medline">20305579</pub-id>
        <pub-id pub-id-type="pmcid">PMC2927728</pub-id></nlm-citation>
      </ref>
      <ref id="ref32">
        <label>32</label>
        <nlm-citation citation-type="web">
        <source>Statistics Canada. Canadian Health Measures Survey 2007/2008 to 2012/2013</source>  
        <year>2013</year>  
        <access-date>2016-11-10</access-date>

        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.statcan.gc.ca/eng/about/er/chmser">http://www.statcan.gc.ca/eng/about/er/chmser</ext-link>
          <ext-link ext-link-type="webcite" xlink:href="6lvLGMsco"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref33">
        <label>33</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Gilson</surname>
            <given-names>ND</given-names>
          </name>
          <name name-style="western">
            <surname>Faulkner</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Murphy</surname>
            <given-names>MH</given-names>
          </name>
          <name name-style="western">
            <surname>Meyer</surname>
            <given-names>MR</given-names>
          </name>
          <name name-style="western">
            <surname>Washington</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Ryde</surname>
            <given-names>GC</given-names>
          </name>
          <name name-style="western">
            <surname>Arbour-Nicitopoulos</surname>
            <given-names>KP</given-names>
          </name>
          <name name-style="western">
            <surname>Dillon</surname>
            <given-names>KA</given-names>
          </name>
        </person-group>
        <article-title>Walk@Work: An automated intervention to increase walking in university employees not achieving 10,000 daily steps</article-title>
        <source>Prev Med</source>  
        <year>2013</year>  
        <month>05</month>  
        <volume>56</volume>  
        <issue>5</issue>  
        <fpage>283</fpage>  
        <lpage>287</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.ypmed.2013.01.022</pub-id>
        <pub-id pub-id-type="medline">23415624</pub-id>
        <pub-id pub-id-type="pii">S0091-7435(13)00036-4</pub-id></nlm-citation>
      </ref>
      <ref id="ref34">
        <label>34</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Leahey</surname>
            <given-names>TM</given-names>
          </name>
          <name name-style="western">
            <surname>Subak</surname>
            <given-names>LL</given-names>
          </name>
          <name name-style="western">
            <surname>Fava</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Schembri</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Thomas</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Xu</surname>
            <given-names>X</given-names>
          </name>
          <name name-style="western">
            <surname>Krupel</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Kent</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Boguszewski</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Kumar</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Weinberg</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Wing</surname>
            <given-names>R</given-names>
          </name>
        </person-group>
        <article-title>Benefits of adding small financial incentives or optional group meetings to a Web-based statewide obesity initiative</article-title>
        <source>Obesity (Silver Spring)</source>  
        <year>2015</year>  
        <month>01</month>  
        <volume>23</volume>  
        <issue>1</issue>  
        <fpage>70</fpage>  
        <lpage>76</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://dx.doi.org/10.1002/oby.20937"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1002/oby.20937</pub-id>
        <pub-id pub-id-type="medline">25384463</pub-id>
        <pub-id pub-id-type="pmcid">PMC4448964</pub-id></nlm-citation>
      </ref>
      <ref id="ref35">
        <label>35</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Saunders</surname>
            <given-names>TJ</given-names>
          </name>
          <name name-style="western">
            <surname>Gray</surname>
            <given-names>CE</given-names>
          </name>
          <name name-style="western">
            <surname>Borghese</surname>
            <given-names>MM</given-names>
          </name>
          <name name-style="western">
            <surname>McFarlane</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Mbonu</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Ferraro</surname>
            <given-names>ZM</given-names>
          </name>
          <name name-style="western">
            <surname>Tremblay</surname>
            <given-names>MS</given-names>
          </name>
        </person-group>
        <article-title>Validity of SC-StepRx pedometer-derived moderate and vigorous physical activity during treadmill walking and running in a heterogeneous sample of children and youth</article-title>
        <source>BMC Public Health</source>  
        <year>2014</year>  
        <volume>14</volume>  
        <fpage>519</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-14-519"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1186/1471-2458-14-519</pub-id>
        <pub-id pub-id-type="medline">24886319</pub-id>
        <pub-id pub-id-type="pii">1471-2458-14-519</pub-id>
        <pub-id pub-id-type="pmcid">PMC4046090</pub-id></nlm-citation>
      </ref>
      <ref id="ref36">
        <label>36</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Colley</surname>
            <given-names>RC</given-names>
          </name>
          <name name-style="western">
            <surname>Barnes</surname>
            <given-names>JD</given-names>
          </name>
          <name name-style="western">
            <surname>Leblanc</surname>
            <given-names>AG</given-names>
          </name>
          <name name-style="western">
            <surname>Borghese</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Boyer</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Tremblay</surname>
            <given-names>MS</given-names>
          </name>
        </person-group>
        <article-title>Validity of the SC-StepMX pedometer during treadmill walking and running</article-title>
        <source>Appl Physiol Nutr Metab</source>  
        <year>2013</year>  
        <month>05</month>  
        <volume>38</volume>  
        <issue>5</issue>  
        <fpage>520</fpage>  
        <lpage>524</lpage>  
        <pub-id pub-id-type="doi">10.1139/apnm-2012-0321</pub-id>
        <pub-id pub-id-type="medline">23668759</pub-id></nlm-citation>
      </ref>
      <ref id="ref37">
        <label>37</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Markland</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Tobin</surname>
            <given-names>V</given-names>
          </name>
        </person-group>
        <article-title>A modification to the Behavioural Regulation in Exercise Questionnaire to include an assessment of amotivation</article-title>
        <source>J Sport Exerc Psychol</source>  
        <year>2004</year>  
        <volume>26</volume>  
        <fpage>191</fpage>  
        <lpage>196</lpage> </nlm-citation>
      </ref>
      <ref id="ref38">
        <label>38</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Wilson</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Rodgers</surname>
            <given-names>W</given-names>
          </name>
          <name name-style="western">
            <surname>Loitz</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Scime</surname>
            <given-names>G</given-names>
          </name>
        </person-group>
        <article-title>It?s who I am...Really!? The importance of integrated regulation in exercise contexts</article-title>
        <source>J Appl Biobehav Res</source>  
        <year>2006</year>  
        <volume>11</volume>  
        <issue>2</issue>  
        <fpage>79</fpage>  
        <lpage>104</lpage>  
        <pub-id pub-id-type="doi">10.1111/j.1751-9861.2006.tb00021.x</pub-id></nlm-citation>
      </ref>
      <ref id="ref39">
        <label>39</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Resnick</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Jenkins</surname>
            <given-names>LS</given-names>
          </name>
        </person-group>
        <article-title>Testing the reliability and validity of the Self-Efficacy for Exercise scale</article-title>
        <source>Nurs Res</source>  
        <year>2000</year>  
        <volume>49</volume>  
        <issue>3</issue>  
        <fpage>154</fpage>  
        <lpage>159</lpage>  
        <pub-id pub-id-type="medline">10882320</pub-id></nlm-citation>
      </ref>
      <ref id="ref40">
        <label>40</label>
        <nlm-citation citation-type="web">
        <source>Random.org</source>  
        <access-date>2016-11-10</access-date>
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.random.org/">https://www.random.org/</ext-link>
          <ext-link ext-link-type="webcite" xlink:href="6lvMvjH6j"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref41">
        <label>41</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Haff</surname>
            <given-names>NM</given-names>
          </name>
          <name name-style="western">
            <surname>Patel</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Lim</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Zhu</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Troxel</surname>
            <given-names>AB</given-names>
          </name>
          <name name-style="western">
            <surname>Asch</surname>
            <given-names>DA</given-names>
          </name>
          <name name-style="western">
            <surname>Volpp</surname>
            <given-names>KG</given-names>
          </name>
        </person-group>
        <article-title>The role of behavioral economic incentive design and demographic characteristics in financial incentive-based approaches to changing health behaviors: a meta-analysis</article-title>
        <source>Am J Health Promot</source>  
        <year>2015</year>  
        <volume>29</volume>  
        <issue>5</issue>  
        <fpage>314</fpage>  
        <lpage>323</lpage>  
        <pub-id pub-id-type="doi">10.4278/ajhp.140714-LIT-333</pub-id>
        <pub-id pub-id-type="medline">25928816</pub-id></nlm-citation>
      </ref>
      <ref id="ref42">
        <label>42</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Mantzari</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Vogt</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Shemilt</surname>
            <given-names>I</given-names>
          </name>
          <name name-style="western">
            <surname>Wei</surname>
            <given-names>Y</given-names>
          </name>
          <name name-style="western">
            <surname>Higgins</surname>
            <given-names>JP</given-names>
          </name>
          <name name-style="western">
            <surname>Marteau</surname>
            <given-names>TM</given-names>
          </name>
        </person-group>
        <article-title>Personal financial incentives for changing habitual health-related behaviors: A systematic review and meta-analysis</article-title>
        <source>Prev Med</source>  
        <year>2015</year>  
        <month>06</month>  
        <volume>75</volume>  
        <fpage>75</fpage>  
        <lpage>85</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://linkinghub.elsevier.com/retrieve/pii/S0091-7435(15)00072-9"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1016/j.ypmed.2015.03.001</pub-id>
        <pub-id pub-id-type="medline">25843244</pub-id>
        <pub-id pub-id-type="pii">S0091-7435(15)00072-9</pub-id>
        <pub-id pub-id-type="pmcid">PMC4728181</pub-id></nlm-citation>
      </ref>
      <ref id="ref43">
        <label>43</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Promberger</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Marteau</surname>
            <given-names>TM</given-names>
          </name>
        </person-group>
        <article-title>When do financial incentives reduce intrinsic motivation? Comparing behaviors studied in psychological and economic literatures</article-title>
        <source>Health Psychol</source>  
        <year>2013</year>  
        <month>09</month>  
        <volume>32</volume>  
        <issue>9</issue>  
        <fpage>950</fpage>  
        <lpage>957</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/24001245"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1037/a0032727</pub-id>
        <pub-id pub-id-type="medline">24001245</pub-id>
        <pub-id pub-id-type="pii">2013-30843-004</pub-id>
        <pub-id pub-id-type="pmcid">PMC3906839</pub-id></nlm-citation>
      </ref>
      <ref id="ref44">
        <label>44</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Sweet</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Tulloch</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Fortier</surname>
            <given-names>MS</given-names>
          </name>
          <name name-style="western">
            <surname>Pipe</surname>
            <given-names>AL</given-names>
          </name>
          <name name-style="western">
            <surname>Reid</surname>
            <given-names>RD</given-names>
          </name>
        </person-group>
        <article-title>Patterns of motivation and ongoing exercise activity in cardiac rehabilitation settings: a 24-month exploration from the TEACH Study</article-title>
        <source>Ann Behav Med</source>  
        <year>2011</year>  
        <month>08</month>  
        <volume>42</volume>  
        <issue>1</issue>  
        <fpage>55</fpage>  
        <lpage>63</lpage>  
        <pub-id pub-id-type="doi">10.1007/s12160-011-9264-2</pub-id>
        <pub-id pub-id-type="medline">21374100</pub-id></nlm-citation>
      </ref>
      <ref id="ref45">
        <label>45</label>
        <nlm-citation citation-type="book">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Biddle</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Mutrie</surname>
            <given-names>N</given-names>
          </name>
        </person-group>
        <source>Psychology of Physical Activity: Determinants, Well-Being, and Interventions</source>  
        <year>2008</year>  
        <publisher-loc>Milton Park, Abingdon, Oxon</publisher-loc>
        <publisher-name>Routledge</publisher-name></nlm-citation>
      </ref>
      <ref id="ref46">
        <label>46</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Volpp</surname>
            <given-names>KG</given-names>
          </name>
          <name name-style="western">
            <surname>Asch</surname>
            <given-names>DA</given-names>
          </name>
          <name name-style="western">
            <surname>Galvin</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Loewenstein</surname>
            <given-names>G</given-names>
          </name>
        </person-group>
        <article-title>Redesigning employee health incentives—lessons from behavioral economics</article-title>
        <source>N Engl J Med</source>  
        <year>2011</year>  
        <month>08</month>  
        <day>4</day>  
        <volume>365</volume>  
        <issue>5</issue>  
        <fpage>388</fpage>  
        <lpage>390</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/21812669"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1056/NEJMp1105966</pub-id>
        <pub-id pub-id-type="medline">21812669</pub-id>
        <pub-id pub-id-type="pmcid">PMC3696722</pub-id></nlm-citation>
      </ref>
      <ref id="ref47">
        <label>47</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Marteau</surname>
            <given-names>TM</given-names>
          </name>
          <name name-style="western">
            <surname>Mantzari</surname>
            <given-names>E</given-names>
          </name>
        </person-group>
        <article-title>The case for pay to quit: A randomized controlled trial of four financial-incentives programmes for smoking cessarion</article-title>
        <source>Nature</source>  
        <year>2015</year>  
        <fpage>523</fpage>  
        <pub-id pub-id-type="doi">10.1038/523040a</pub-id></nlm-citation>
      </ref>
      <ref id="ref48">
        <label>48</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Mitchell</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Goodman</surname>
            <given-names>JM</given-names>
          </name>
          <name name-style="western">
            <surname>Alter</surname>
            <given-names>DA</given-names>
          </name>
          <name name-style="western">
            <surname>Oh</surname>
            <given-names>PI</given-names>
          </name>
          <name name-style="western">
            <surname>Faulkner</surname>
            <given-names>GE</given-names>
          </name>
        </person-group>
        <article-title>“Will walk for groceries”: acceptability of financial health incentives among Canadian cardiac rehabilitation patients</article-title>
        <source>Psychol Health</source>  
        <year>2014</year>  
        <volume>29</volume>  
        <issue>9</issue>  
        <fpage>1032</fpage>  
        <lpage>1043</lpage>  
        <pub-id pub-id-type="doi">10.1080/08870446.2014.904863</pub-id>
        <pub-id pub-id-type="medline">24731024</pub-id></nlm-citation>
      </ref>
      <ref id="ref49">
        <label>49</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Mitchell</surname>
            <given-names>MS</given-names>
          </name>
          <name name-style="western">
            <surname>Faulkner</surname>
            <given-names>GE</given-names>
          </name>
        </person-group>
        <article-title>On supplementing “foot in the door” incentives for eHealth program engagement</article-title>
        <source>J Med Internet Res</source>  
        <year>2014</year>  
        <month>07</month>  
        <day>25</day>  
        <volume>16</volume>  
        <issue>7</issue>  
        <fpage>e179</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.jmir.org/2014/7/e179/"/>
        </comment>  
        <pub-id pub-id-type="doi">10.2196/jmir.3701</pub-id>
        <pub-id pub-id-type="medline">25092221</pub-id>
        <pub-id pub-id-type="pii">v16i7e179</pub-id>
        <pub-id pub-id-type="pmcid">PMC4129124</pub-id></nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
