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JMIR Research Protocols
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Vol 1, No 2 (2012) - Jul-Dec


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Randomized Controlled Trials (eHealth)

Mobile.net: Mobile Telephone Text Messages to Encourage Adherence to Medication and to Follow up With People With Psychosis: Methods and Protocol for a Multicenter Randomized Controlled Two-Armed Trial

Maritta Välimäki, Heli Hätönen, Clive E Adams

JMIR Res Protoc 2012 (Aug 02); 1(2):e8

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Background: Schizophrenia is a high-cost, chronic, serious mental illness. There is a clear need to improve treatments and expand access to care for persons with schizophrenia, but simple, tailored interventions are missing. Objective: To evaluate the impact of tailored mobile telephone text messages to encourage adherence to medication and to follow up with people with psychosis at 12 months. Methods: Mobile.Net is a pragmatic randomized trial with inpatient psychiatric wards allocated to...

Design and Methods for a Comparative Effectiveness Pilot Study: Virtual World vs. Face-to-Face Diabetes Self-Management

Milagros C. Rosal, Robin Heyden, Roanne Mejilla, Maria Rizzo DePaoli, Chetty Veerappa, John M. Wiecha

JMIR Res Protoc 2012 (Dec 17); 1(2):e24

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Background: Type 2 diabetes (diabetes) is a serious threat to public health in the United States and disproportionally affects many racial/ethnic minority groups, including African Americans. Limited access to treatment and high attrition rates further contribute to health disparities in diabetes-related morbidity and mortality among minorities. Greater opportunities for increasing access and decreasing barriers to treatment are needed. Technology-based interventions have potential for...

A Serious Video Game to Increase Fruit and Vegetable Consumption Among Elementary Aged Youth (Squire’s Quest! II): Rationale, Design, and Methods

Debbe Thompson, Riddhi Bhatt, Melanie Lazarus, Karen Cullen, Janice Baranowski, Tom Baranowski

JMIR Res Protoc 2012 (Nov 21); 1(2):e19

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Background: Youths eat fewer fruits and vegetables than recommended. Effective methods are needed to increase and maintain their fruit and vegetable consumption. Goal setting has been an effective behavior change procedure among adults, but has had limited effectiveness among youths. Implementation intentions are specific plans to facilitate goal attainment. Redefining goal setting to include implementation intentions may be an effective way to increase effectiveness. Video games offer a...

A Personalized Automated Messaging System to Improve Adherence to Prostate Cancer Screening: Research Protocol

Michael Juntao Yuan, Emily T Hébert, Ron K Johnson, Ju Long, Elizabeth A. Vandewater, Andrew J. Vickers

JMIR Res Protoc 2012 (Nov 28); 1(2):e20

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Background: Public adherence to cancer screening guidelines is poor. Patient confusion over multiple recommendations and modalities for cancer screening has been found to be a major barrier to screening adherence. Such problems will only increase as screening guidelines and timetables become individualized. Objective: We propose to increase compliance with cancer screening through two-way rich media mobile messaging based on personalized risk assessment. Methods: We propose to develop and...

Proposals (eHealth)

A Collaborative Quality Improvement Model and Electronic Community of Practice to Support Sepsis Management in Emergency Departments: Investigating Care Harmonization for Provincial Knowledge Translation

Kendall Ho, Julian Marsden, Sandra Jarvis-Selinger, Helen Novak Lauscher, Noreen Kamal, Rob Stenstrom, David Sweet, Ran D Goldman, Grant Innes

JMIR Res Protoc 2012 (Jul 12); 1(2):e6

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Emergency medicine departments within several organizations are now advocating the adoption of early intervention guidelines for patients with the signs and symptoms of sepsis. This proposed research will lead to a comprehensive understanding of how diverse emergency department (ED) sites across British Columbia (BC), Canada, engage in a quality improvement collaborative to lead to improvements in time-based process measures and clinical outcomes for septic patients in EDs. To address the...

Formative Studies and eHealth/mHealth Development

Development of Smartphone Applications for Nutrition and Physical Activity Behavior Change

Lana Hebden, Amelia Cook, Hidde P. van der Ploeg, Margaret Allman-Farinelli

JMIR Res Protoc 2012 (Aug 22); 1(2):e9

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Background: Young adults (aged 18 to 35) are a population group at high risk for weight gain, yet we know little about how to intervene in this group. Easy access to treatment and support with self-monitoring of their behaviors may be important. Smartphones are gaining in popularity with this population group and software applications (“apps”) used on these mobile devices are a novel technology that can be used to deliver brief health behavior change interventions directly to...

A Web-Based Intervention for Health Professionals and Patients to Decrease Cardiovascular Risk Attributable to Physical Inactivity: Development Process

Barbara Sassen, Gerjo Kok, Ilse Mesters, Rik Crutzen, Anita Cremers, Luc Vanhees

JMIR Res Protoc 2012 (Dec 14); 1(2):e21

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Background: Patients with cardiovascular risk factors can reduce their risk of cardiovascular disease by increasing their physical activity and their physical fitness. According to the guidelines for cardiovascular risk management, health professionals should encourage their patients to engage in physical activity. Objective: In this paper, we provide insight regarding the systematic development of a Web-based intervention for both health professionals and patients with cardiovascular risk...

Technical Implementation of a Multi-Component, Text Message–Based Intervention for Persons Living with HIV

Robert D Furberg, Jennifer D Uhrig, Carla M Bann, Megan A Lewis, Jennie L Harris, Peyton Williams, Curtis Coomes, Nicole Martin, Lisa Kuhns

JMIR Res Protoc 2012 (Nov 16); 1(2):e17

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Background: Men who have sex with men (MSM) continue to be severely and disproportionately affected by the HIV/AIDS (human immunodeficiency virus/acquired immune deficiency syndrome) epidemic in the United States. Effective antiretroviral therapy has altered the HIV epidemic from being an acute disease to a chronic, manageable condition for many people living with HIV. The pervasiveness, low cost, and convenience of Short Message Service (SMS) suggests its potential suitability for...

Telemedicine Consultations: An Alternative Model to Increase Access to Diabetes Specialist Care in Underserved Rural Communities

Frederico G. Toledo, Amy Triola, Kristine Ruppert, Linda M. Siminerio

JMIR Res Protoc 2012 (Nov 07); 1(2):e14

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Background: Diabetes care in rural communities often suffers because of physician shortages. When patients need to see an endocrinologist, long-distance travel to urban centers can constitute a barrier to care. Objective: To address this problem, we tested whether diabetes telemedicine consultations would be acceptable to rural patients and their primary care providers as an alternative care model. Methods: Twenty-five patients with diabetes in a rural, medically underserved community...

Computer-Assisted School-Based Asthma Management: A Pilot Study

Renée JG Arnold, Jeanette A. Stingone, Luz Claudio

JMIR Res Protoc 2012 (Nov 13); 1(2):e15

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Background: The high prevalence of asthma among children continues to be a major public health issue. In particular, low-income African-American and Hispanic children often receive asthma care in the emergency department and lack access to continuity of care. Objective: The aim of the current study was to test the feasibility of implementing a computerized program for empowering low-income children with asthma to manage their own disease. This pilot program consisted of a guided,...

Filling the Gaps in a Fragmented Health Care System: Development of the Health and Welfare Information Portal (ZWIP)

Sarah HM Robben, Mirjam Huisjes, Theo van Achterberg, Sytse U Zuidema, Marcel GM Olde Rikkert, Henk J Schers, Maud M Heinen, René JF Melis, For The ZOWEL NN Study Group

JMIR Res Protoc 2012 (Sep 19); 1(2):e10

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Background: Current health care systems are not optimally designed to meet the needs of our aging populations. First, the fragmentation of care often results in discontinuity of care that can undermine the quality of care provided. Second, patient involvement in care decisions is not sufficiently facilitated. Objective: To describe the development and the content of a program aimed at: (1) facilitating self-management and shared decision making by frail older people and informal caregivers,...

Electronic Problem-Solving Treatment: Description and Pilot Study of an Interactive Media Treatment for Depression

James Albert Cartreine, Steven E Locke, Jay C Buckey, Luis Sandoval, Mark T Hegel

JMIR Res Protoc 2012 (Sep 25); 1(2):e11

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Background: Computer-automated depression interventions rely heavily on users reading text to receive the intervention. However, text-delivered interventions place a burden on persons with depression and convey only verbal content. Objective: The primary aim of this project was to develop a computer-automated treatment for depression that is delivered via interactive media technology. By using branching video and audio, the program simulates the experience of being in therapy with a master...

Decision Support and the Effectiveness of Web-based Delivery and Information Tailoring for Bowel Cancer Screening: An Exploratory Study

Ingrid H Flight, Carlene J Wilson, Ian T Zajac, Elizabeth Hart, Jane A McGillivray

JMIR Res Protoc 2012 (Sep 26); 1(2):e12

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Background: Colorectal cancer (CRC) is the third most commonly diagnosed cancer in males and the second in females throughout the developed world. Population screening using fecal occult blood tests (FOBTs) facilitates early detection and greater chance of survival, but participation rates are low. We developed a Web-based decision tool to provide information tailored to an individual’s decision stage for CRC screening and attitude toward screening utilizing the Preventive Health Model...

Usability Study of a Computer-Based Self-Management System for Older Adults with Chronic Diseases

Calvin Or, Da Tao

JMIR Res Protoc 2012 (Nov 08); 1(2):e13

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Background: Usability can influence patients’ acceptance and adoption of a health information technology. However, little research has been conducted to study the usability of a self-management health care system, especially one geared toward elderly patients. Objective: This usability study evaluated a new computer-based self-management system interface for older adults with chronic diseases, using a paper prototype approach. Methods: Fifty older adults with different chronic diseases...

Integrating Psychological Theory Into the Design of an Online Intervention for Sexual Health: The Sexunzipped Website

Kenneth Carswell, Ona McCarthy, Elizabeth Murray, Julia V Bailey

JMIR Res Protoc 2012 (Nov 19); 1(2):e16

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Background: The Internet can provide a confidential and convenient medium for sexual health promotion for young people. Objective: This paper describes the development of an interactive, theory-based website (Sexunzipped) aimed at increasing safe sexual behavior of young people, as well as an outline of the evaluation protocol. Methods: The website focuses on safer sex, relationships, and sexual pleasure. An overview of the site is provided, including a description of the theoretical...

Web-Based Intervention for Postpartum Depression: Formative Research and Design of the MomMoodBooster Program

Brian G. Danaher, Jeannette Milgrom, John R. Seeley, Scott Stuart, Charlene Schembri, Milagra S. Tyler, Jennifer Ericksen, Whitney Lester, Alan W. Gemmill, Peter Lewinsohn

JMIR Res Protoc 2012 (Nov 22); 1(2):e18

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Background: Postpartum depression is a significant public health problem affecting approximately 13% of women. There is strong evidence supporting Cognitive Behavioral Therapy (CBT) for successful psychosocial treatment. This treatment model combines cognitive and behavioral strategies to address pessimism, attributions for failure, low self-esteem, low engagement in pleasant activities, social withdrawal, anxiety, and low social support. Encouraging results have been reported for using...

Developing an Internet-Based Support System for Adolescents with Depression

Maritta Välimäki, Marjo Kurki, Heli Hätönen, Marita Koivunen, Maarit Selander, Simo Saarijärvi, Minna Anttila

JMIR Res Protoc 2012 (Dec 12); 1(2):e22

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Background: Depression is the most common mental health problem among adolescents. Despite policy guidance and governmental support to develop usable mental health services, there is still a lack of easily accessible and modern interventions available for adolescents in Finland’s majority official language. Objective: Our objective was to develop a user-friendly and feasible Internet-based support system for adolescents with depression. Methods: The Internet-based support system for...

Development and Formative Evaluation of a Visual E-Tool to Help Decision Makers Navigate the Evidence Around Health Financing

Jolene Skordis-Worrall, Anni-Maria Pulkki-Brännström, Martin Utley, Gayatri Kembhavi, Nouria Bricki, Xavier Dutoit, Mikey Rosato, Christina Pagel

JMIR Res Protoc 2012 (Dec 21); 1(2):e25

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Background: There are calls for low and middle income countries to develop robust health financing policies to increase service coverage. However, existing evidence around financing options is complex and often difficult for policy makers to access. Objective: To summarize the evidence on the impact of financing health systems and develop an e-tool to help decision makers navigate the findings. Methods: After reviewing the literature, we used thematic analysis to summarize the impact of 7...

Non-Randomized Study Protocols and Methods (Non-eHealth)

Lifetime Occupational Physical Activity and Musculoskeletal Aging in Middle-Aged Men and Women in Denmark: Retrospective Cohort Study Protocol and Methods

Anne Møller, Ole Steen Mortensen, Susanne Reventlow, Peder Georg Skov, Johan Hviid Andersen, Tine Steen Rubak, Åse Marie Hansen, Lars L Andersen, Rikke Lund, Merete Osler, Ulla Christensen, Kirsten Avlund

JMIR Res Protoc 2012 (Jul 27); 1(2):e7

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Background: Physical function is essential for performing most aspects of daily life and musculoskeletal aging leads to a decline in physical function. The onset and rate of this process vary and are influenced by environmental, genetic, and hormonal factors. Although everyone eventually experiences musculoskeletal aging, it is beneficial to study the factors that influence the aging process in order to prevent disability. The role of occupational physical activity in the musculoskeletal...

Mobile Health (mhealth)

Initial Evaluation of an Electronic Symptom Diary for Adolescents with Cancer

Christina Baggott, Faith Gibson, Beatriz Coll, Richard Kletter, Paul Zeltzer, Christine Miaskowski

JMIR Res Protoc 2012 (Dec 11); 1(2):e23

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Background: The delivery of optimal care depends on accurate communication between patients and clinicians regarding untoward symptoms. Documentation of patients’ symptoms necessitates reliance on memory, which is often imprecise. We developed an electronic diary (eDiary) for adolescents and young adults (AYAs) with cancer to record symptoms. Objective: The purpose of this paper is to describe the utility of an eDiary designed for AYAs with cancer, including dependability of the mobile...