@Article{info:doi/10.2196/resprot.6846, author="Kanitkar, Anuprita and Szturm, Tony and Parmar, Sanjay and Gandhi, BC Dorcas and Rempel, Ruth Gina and Restall, Gayle and Sharma, Monika and Narayan, Amitesh and Pandian, Jeyaraj and Naik, Nilashri and Savadatti, R. Ravi and Kamate, Appasaheb Mahesh", title="The Effectiveness of a Computer Game-Based Rehabilitation Platform for Children With Cerebral Palsy: Protocol for a Randomized Clinical Trial", journal="JMIR Res Protoc", year="2017", month="May", day="18", volume="6", number="5", pages="e93", keywords="repetitive task practice", keywords="cerebral palsy", keywords="fine motor skills", keywords="game-based exercise", keywords="randomized controlled trial", keywords="upper extremity function", abstract="Background: It is difficult to engage young children with cerebral palsy (CP) in repetitive, tedious therapy. As such, there is a need for innovative approaches and tools to motivate these children. We developed the low-cost, computer game-based rehabilitation platform CGR that combines fine manipulation and gross movement exercises with attention and planning game activities appropriate for young children with CP. Objective: The objective of this study is to provide evidence of the therapeutic value of CGR to improve upper extremity (UE) motor function for children with CP. Methods: This randomized controlled, single-blind, clinical trial with an active control arm will be conducted at 4 sites. Children diagnosed with CP between the ages of 4 and 10 years old with moderate UE impairments and fine motor control abnormalities will be recruited. Results: We will test the difference between experimental and control groups using the Quality of Upper Extremity Skills Test (QUEST) and Peabody Developmental Motor Scales, Second Edition (PDMS-2) outcome measures. The parents of the children and the therapist experiences with the interventions and tools will be explored using semi-structured interviews using the qualitative description approach. Conclusions: This research protocol, if effective, will provide evidence for the therapeutic value and feasibility of CGR in the pediatric rehabilitation of UE function. Trial Registration: Clinicaltrials.gov NCT02728375; http:https://clinicaltrials.gov/ct2/show/NCT02728375 (Archived by WebCite at http://www.webcitation.org/6qDjvszvh) ", doi="10.2196/resprot.6846", url="http://www.researchprotocols.org/2017/5/e93/", url="http://www.ncbi.nlm.nih.gov/pubmed/28526673" }