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JMIR Research Protocols
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Vol 2, No 1 (2013) - Jan-Jun


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Randomized Controlled Trials (funded, already peer-reviewed)

Capitalizing on the Teachable Moment: Osteoarthritis Physical Activity and Exercise Net for Improving Physical Activity in Early Knee Osteoarthritis

Linda C Li, Sydney Lineker, Jolanda Cibere, Valorie A Crooks, Catherine A Jones, Jacek A Kopec, Scott A Lear, James Pencharz, Ryan E Rhodes, John M Esdaile

JMIR Res Protoc 2013 (May 09); 2(1):e17

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Background: Practice guidelines emphasize the use of exercise and weight reduction as the first line of management for knee osteoarthritis (OA). However, less than half of the people with mild OA participate in moderate intensity physical activity. Given that physical activities have been shown to reduce pain, improve quality of life, and have the potential to reduce the progression of joint damage, many people with OA are missing the benefits of this inexpensive intervention. Objective: The...

Proposals (eHealth)

InsuOnline, a Serious Game to Teach Insulin Therapy to Primary Care Physicians: Design of the Game and a Randomized Controlled Trial for Educational Validation

Leandro Arthur Diehl, Rodrigo Martins Souza, Juliano Barbosa Alves, Pedro Alejandro Gordan, Roberto Zonato Esteves, Maria Lúcia Silva Germano Jorge, Izabel Cristina Meister Coelho

JMIR Res Protoc 2013 (Jan 21); 2(1):e5

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Background: Physicians´ lack of knowledge contributes to underuse of insulin and poor glycemic control in adults with diabetes mellitus (DM). Traditional continuing medical education have limited efficacy, and new approaches are required. Objective: We report the design of a trial to assess the educational efficacy of InsuOnline, a game for education of primary care physicians (PCPs). The goal of InsuOnline was to improve appropriate initiation and adjustment of insulin for the...

Formative Studies and eHealth/mHealth Development

Feasibility of a Personal Health Technology-Based Psychological Intervention for Men with Stress and Mood Problems: Randomized Controlled Pilot Trial

Päivi Lappalainen, Kirsikka Kaipainen, Raimo Lappalainen, Henna Hoffrén, Tero Myllymäki, Marja-Liisa Kinnunen, Elina Mattila, Antti P. Happonen, Heikki Rusko, Ilkka Korhonen

JMIR Res Protoc 2013 (Jan 09); 2(1):e1

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Background: Work-related stress is a significant problem for both people and organizations. It may lead to mental illnesses such as anxiety and depression, resulting in increased work absences and disabilities. Scalable interventions to prevent and manage harmful stress can be delivered with the help of technology tools to support self-observations and skills training. Objective: The aim of this study was to assess the feasibility of the P4Well intervention in treatment of stress-related...

The SADI Personal Health Lens: A Web Browser-Based System for Identifying Personally Relevant Drug Interactions

Ben Vandervalk, E Luke McCarthy, José Cruz-Toledo, Artjom Klein, Christopher J O Baker, Michel Dumontier, Mark D Wilkinson

JMIR Res Protoc 2013 (Apr 05); 2(1):e14

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Background: The Web provides widespread access to vast quantities of health-related information that can improve quality-of-life through better understanding of personal symptoms, medical conditions, and available treatments. Unfortunately, identifying a credible and personally relevant subset of information can be a time-consuming and challenging task for users without a medical background. Objective: The objective of the Personal Health Lens system is to aid users when reading...

Web-Based eHealth to Support Counseling in Routine Well-Child Care: Pilot Study of E-health4Uth Home Safety

Mirjam Elisabeth Johanna van Beelen, Ineke Vogel, Tinneke Monique Jozef Beirens, Gitte Caroline Kloek, Paul den Hertog, Monique Désirée van der Veen, Hein Raat

JMIR Res Protoc 2013 (Feb 11); 2(1):e9

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Background: Providing safety education to parents of young children is important in the prevention of unintentional injuries in or around the home. We developed a Web-based, tailored safety advice module to support face-to-face counseling in the setting of preventive youth health care (E-health4Uth home safety) in order to improve the provision of safety information for parents of young children. Objective: This pilot study evaluated a Web-based, tailored safety advice module (E-health4Uth...

Usability Evaluation of an Online, Tailored Self-Management Intervention for Chronic Obstructive Pulmonary Disease Patients Incorporating Behavior Change Techniques

Viola Voncken-Brewster, Albine Moser, Trudy van der Weijden, Zsolt Nagykaldi, Hein de Vries, Huibert Tange

JMIR Res Protoc 2013 (Jan 16); 2(1):e3

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Background: An eHealth intervention using computer tailored technology including several behavior change techniques was developed to support the self-management of chronic obstructive pulmonary disease patients. Objective: The goal of this study was to evaluate and improve the usability of the eHealth intervention. Methods: We conducted a usability evaluation with 8 chronic obstructive pulmonary disease patients, with a mixed methods design. We improved the usability through iterative cycles...

Role of the Working Alliance on Treatment Outcome in Tailored Internet-Based Cognitive Behavioural Therapy for Anxiety Disorders: Randomized Controlled Pilot Trial

Lise Bergman Nordgren, Per Carlbring, Emma Linna, Gerhard Andersson

JMIR Res Protoc 2013 (Jan 18); 2(1):e4

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Background: Internet-based cognitive behavioral therapy (ICBT) is a form of guided self-help that has been found to be effective for addressing several problems. The target for this type of therapy is usually restricted to one specific disorder. Tailoring the treatment widens the scope of ICBT in that it can address comorbid conditions directly. Objectives: The working, or therapeutic, alliance has been found to predict outcome in studies of face-to-face therapy. The extent to which these...

Barriers and Facilitators of Online Patient Portals to Personal Health Records Among Persons Living With HIV: Formative Research

Amneris E Luque, Adjuah van Keken, Paul Winters, Michael C Keefer, Mechelle Sanders, Kevin Fiscella

JMIR Res Protoc 2013 (Jan 22); 2(1):e8

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Background: Federal meaningful use standards are promoting adoption of online portals to personal health records (PHRs). However, relatively little is known regarding barriers and facilitators for vulnerable groups such as persons living with human immunodeficiency virus (PLWH). Objective: The objective of this study was to assess barriers and facilitators to use of online PHRs among PLWH. Methods: We conducted formative research using a written waiting room survey among 120 PLWH regarding...

Constructing a Theory- and Evidence-Based Treatment Rationale for Complex eHealth Interventions: Development of an Online Alcohol Intervention Using an Intervention Mapping Approach

Håvar Brendryen, Ayna B. Johansen, Sverre Nesvåg, Gerjo Kok, Fanny Duckert

JMIR Res Protoc 2013 (Jan 23); 2(1):e6

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Background: Due to limited reporting of intervention rationale, little is known about what distinguishes a good intervention from a poor one. To support improved design, there is a need for comprehensive reports on novel and complex theory-based interventions. Specifically, the emerging trend of just-in-time tailoring of content in response to change in target behavior or emotional state is promising. Objective: The objective of this study was to give a systematic and comprehensive...

Development and Usability Testing of an Internet Intervention to Increase Physical Activity in Overweight Adolescents

Kirsti Riiser, Knut Løndal, Yngvar Ommundsen, Turid Sundar, Sølvi Helseth

JMIR Res Protoc 2013 (Jan 28); 2(1):e7

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Background: Internet interventions may provide opportunities for low threshold counseling using feedback to guide and support health behavior, including increased physical activity. Research shows that overweight and obese adolescents are less physically active than their peers of normal weight. There are good reasons to believe that Internet-based interventions may be particularly suitable for motivating adolescents to increase physical activity, but we need to gain further knowledge of what...

Wellness Partners: Design and Evaluation of a Web-Based Physical Activity Diary with Social Gaming Features for Adults

Marientina Gotsis, Hua Wang, Donna Spruijt-Metz, Maryalice Jordan-Marsh, Thomas William Valente

JMIR Res Protoc 2013 (Feb 01); 2(1):e10

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Background: The United States is currently in an age of obesity and inactivity despite increasing public awareness and scientific knowledge of detrimental long-term health effects of this lifestyle. Behavior-tracking diaries offer an effective strategy for physical activity adherence and weight management. Furthermore, Web-based physical activity diaries can engage meaningful partners in people’s social networks through fun online gaming interactions and generate motivational mechanisms...

Development and Formative Evaluation of a Web-Based Self-Management Exercise and Diet Intervention Program With Tailored Motivation and Action Planning for Cancer Survivors

Myung Kyung Lee, Hyeoun-Ae Park, Young Ho Yun, Yoon Jung Chang

JMIR Res Protoc 2013 (Feb 13); 2(1):e11

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Background: Most dietary and exercise interventions developed to date for cancer survivors have employed intensive clinic-based face-to-face counseling sessions. However, when the clinic-based face-to-face intervention ends, the participants cannot receive feedback from the experts, and the motivation for regular exercise and diet practices decreases. One way to overcome the shortcomings of clinic-based face-to-face intervention is to employ the Internet to this end. To maximize effectiveness...

Designing iCanFit: A Mobile-Enabled Web Application to Promote Physical Activity for Older Cancer Survivors

Yan Hong, Deborah Vollmer Dahlke, Marcia Ory, Angela Hochhalter, Jana Reynolds, Ninfa Pena Purcell, Divya Talwar, Nola Eugene

JMIR Res Protoc 2013 (Feb 14); 2(1):e12

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Background: Most older cancer survivors (OCS) do not engage in regular physical activity (PA) despite well-known health benefits. With the increased use of mobile technologies among older adults, mobile tools may be an effective method to deliver PA promotion programs for OCS. Objective: To document the process of designing an OCS-friendly mobile-enabled Web application of PA promotion program. Methods: Mixed methods encompassing group discussions, individual interviews, and brief surveys...

User Perceptions of a Dementia Risk Reduction Website and Its Promotion of Behavior Change

Maree Farrow

JMIR Res Protoc 2013 (Apr 18); 2(1):e15

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Background: Several modifiable health and lifestyle factors are consistently associated with dementia risk and it is estimated that significantly fewer people would develop dementia if the incidence of risk factors could be reduced. Despite this, Australians’ awareness of the health and lifestyle factors associated with dementia risk is low. Within a national community education campaign, Alzheimer’s Australia developed a dementia risk reduction website providing information...

Evaluation of Active Transition, a Website-Delivered Physical Activity Intervention for University Students: Pilot Study

Matthew Kwan, Guy Faulkner, Steven Bray

JMIR Res Protoc 2013 (May 06); 2(1):e16

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Background: While physical activity in individuals tends to decline steadily with age, there are certain periods where this decline occurs more rapidly, such as during early adulthood. Interventions aimed at attenuating the declines in physical activity during this transition period appear warranted. Objective: The purpose of the study was to test the feasibility and efficacy of a theoretically informed, website-delivered physical activity intervention aimed at students entering university....

Non-Randomized Study Protocols and Methods (Non-eHealth)

The Natural History of Spina Bifida in Children Pilot Project: Research Protocol

Ann I. Alriksson-Schmidt, Judy K. Thibadeau, Mark E. Swanson, David Marcus, Kari L. Carris, Csaba Siffel, Elisabeth Ward

JMIR Res Protoc 2013 (Jan 25); 2(1):e2

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Background: Population-based empirical information to inform health care professionals working with children with spina bifida currently is lacking. Spina bifida is a highly complex condition that not only affects mobility but many additional aspects of life. We have developed a pilot project that focuses on a broad range of domains: surgeries, development and learning, nutrition and physical growth, mobility and functioning, general health, and family demographics. Specifically, we will: (1)...

Terminology, Taxonomy, and Facilitation of Motor Learning in Clinical Practice: Protocol of a Delphi Study

Melanie Kleynen, Michel HC Bleijlevens, Anna JHM Beurskens, Sascha M Rasquin, Jos Halfens, Mark R Wilson, Rich S Masters, Monique A Lexis, Susy M Braun

JMIR Res Protoc 2013 (May 17); 2(1):e18

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Background: Facilitating motor learning in patients during clinical practice is complex, especially in people with cognitive impairments. General principles of motor learning are available for therapists to use in their practice. However, the translation of evidence from the different fields of motor learning for use in clinical practice is problematic due to lack of uniformity in definition and taxonomy of terms related to motor learning. Objective: The objective of this paper was to...

Research Priorities Setting

Improving Primary Health Care in Chronic Musculoskeletal Conditions through Digital Media: The PEOPLE Meeting

Linda C Li, Cheryl Cott, C Allyson Jones, Elizabeth M Badley, Aileen M Davis, PEOPLE Meeting Participants

JMIR Res Protoc 2013 (Mar 08); 2(1):e13

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Background: Musculoskeletal (MSK) conditions are the most common cause of severe chronic pain and disability worldwide. Despite the impact of these conditions, disparity exists in accessing high quality basic care. As a result, effective treatments do not always reach people who need services. The situation is further hampered by the current models of care that target resources to a limited area of health services (eg, joint replacement surgery), rather than the entire continuum of MSK...