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Ongoing Trials, Grant Proposals, Formative Research, Methods, Early Results
JMIR Research Protocols (ISSN 1929-0748) is a unique Pubmed-indexed journal, publishing peer-reviewed, openly accessible research ideas and grant proposals, study and trial protocols, reports of ongoing research, current methods and approaches, and preliminary results from pilot studies or formative research informing the design of medical and health-related research and technology innovations.
JMIR Res Protoc is a journal spin-off of JMIR, the worlds' leading medical journal in health sciences / health services research and health informatics (JMIR Impact Factor 2016: 5.175).
While the original focus was on eHealth studies, JMIR Res Protoc now publishes protocols and grant proposals in all areas of medicine (and their peer-review reports, if available), as well as feasibility studies, early reports and formative/process evaluations of ongoing studies and descriptions of the development and pilot evaluations of innovations and software applications or other interventions.
JMIR Res Protoc is fully open access, with full text articles deposited in PubMed Central.
Publishing research protocols, grant proposals, pilot/feasibility studies and early reports of ongoing and planned work encourages collaboration and early feedback, and reduces duplication of effort.
JMIR Res Protoc will be a valuable ressource for researchers who want to learn about current research methodologies and how to write a winning grant proposal.
JMIR Res Protoc creates an early scientific record for researchers who have developed novel methodologies, software, innovations or elaborate protocols.
JMIR Res Protoc provides a "dry-run" for peer-review of the final results paper, and allows feedback/critique of the methods, often while they still can be fixed.
JMIR Res Protoc faciliates subsequent publication of results demonstrating that the methodology has already been reviewed, and reduces the effort of writing up the results, as the protocol can be easily referenced.
JMIR Res Protoc demonstrates to reviewers of subsequent results papers that authors followed and adhered to carefully developed and described a-priori methods.
Studies whose protocols or grant proposal have been accepted in JMIR Res Protoc are "in principle accepted" for subsequent publication of results in other JMIR journals as long as authors adhere to their original protocol - regardless of study results (even if they are negative), reducing publication bias in medicine.
Authors publishing their protocols in JMIR Res Protoc will receive a 20% discount on the article processing fee if they publish their results in another journal of the JMIR journal family (for example, JMIR for ehealth studies, i-JMR for others).
Need more reasons? Read the Knowledge Base article on "Why should I publish my protocol/grant proposal"!
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Smart home technologies, integrated into housing for people with brain impairment, are emerging as a useful component of support delivery to this group. To promote successful uptake and sustained use...
Smart home technologies, integrated into housing for people with brain impairment, are emerging as a useful component of support delivery to this group. To promote successful uptake and sustained use of such technologies, recent research recommends that renewed focus be placed on technology support services, including training. This paper presents a systematic training approach for use with people with brain impairment, and outlines a multiple baseline, single-case experimental design methodology that will be used to evaluate its effectiveness. Participants will be recruited from new models of support housing with integrated smart home technology. The future evaluation of this training approach will offer new insights into the technology-related training needs of people with brain impairment, and assist therapists in planning for the technology support services that will need to accompany provision of new devices or systems to clients.
The variety of alarms from all types of medical devices has increased from six to 40 in the last three decades, with today’s most critically ill patients experiencing as many as 45 alarms per hour....
The variety of alarms from all types of medical devices has increased from six to 40 in the last three decades, with today’s most critically ill patients experiencing as many as 45 alarms per hour. The high proportion of non-actionable alarms emanating from medical devices has been associated with increased clinical staff desensitization to all types of alarms. Alarm fatigue has been identified as a critical safety issue that can lead to potentially dangerous delays or non-response to actionable alarms resulting in serious patient injury and death. To date, most research on medical device alarms has focused on the non actionable alarms of physiological monitoring devices, with few published reports related to the types and frequencies of actionable infusion pump alarms. The objectives of this study protocol are to establish baseline data related to the types and frequency of infusion pump alarms associated with approximately 550,000 infusions over a 60 day period at 32 US hospitals. In addition, infusion pump alarm types and frequencies will be analyzed to assess consistencies and inconsistencies between hospitals and hospital units, and establish what factors may contribute to these differences. Understanding the incidences and characteristics of infusion pump alarms will result in more informed quality improvement recommendations to decrease and/or modify infusion pump alarms and potentially reduce clinical staff alarm fatigue and improve patient safety.
Background: Incarcerated populations have increased in the last 20 years and over 12 million individuals cycle in and out of jails each year. Previous research has predominately focused on the prison...
Background: Incarcerated populations have increased in the last 20 years and over 12 million individuals cycle in and out of jails each year. Previous research has predominately focused on the prison population. However, a substantial gap exists in understanding the health, wellbeing, and health care utilization patterns in jail populations. Objective: The Health Disparities in Jail Populations pilot study has five main objectives: (1) define “super users” of the jail system, individuals characterized by high incarceration rates; (2) describe and compare characteristics of incarcerated individuals; (3) identify jail associated health disparities; (4) estimate associations between incarceration and health; and (5) model patterns in healthcare and jail utilization. Methods: The project is functionally separated into two processes: a comprehensive secondary data analysis and primary data collection that includes a cross-sectional health survey and collection of biological samples. The secondary data analysis includes the analysis of eight distinct databases: (1) the Superior Court of Arizona, (2) North Country Health Care; (3) Health Choice Integrated Care (behavioral health); (4) Criminal Justice Information Services; (5) Correctional Electronic Medical Records; (6) iLEADS (the jail’s inmate records system); (7) Arizona Department of Health Services; and (8) Coconino County Health Department. We will perform data integration employing an honest broker design to provide a longitudinal view of an individual across multiple community-based health providers, criminal justice databases, and jail-based health services. We will also administer a cross-sectional health survey among 200 Coconino County Detention Facility inmates. The survey includes in-depth questions about health status indicators, health history, health care system utilization, substance use practices, behavioral health, and psychiatric diagnoses. Concurrent with the survey administration we will collect MRSA/MSSA (S. aureus samples from the nose) and dental microbiome (S. sobrinus and S. mutans samples from the mouth) from consenting participants. Results: To date, we have permission to link data across acquired databases. We also have access to the Coconino County Detention Facility inmates. To date, of the 58 inmates interviewed, we have permission from 97% to access and link electronic medical and incarceration records to their survey responses and 95% of interviewed inmates have given nasal and buccal swabs for analysis of S. aureus and the dental microbiome. Conclusions: The Health Disparities in Jail Populations study is designed to increase the understanding of health needs and healthcare utilization patterns among jail populations. Our findings will allow for identification of points of intervention throughout the criminal justice and health care systems to improve health and reduce health disparities among jail inmates.
Background Most of the global burden of cervical cancer is experienced in countries with limited resources, and mortality from cervical cancer is the most common cause of cancer-related deaths among...
Background Most of the global burden of cervical cancer is experienced in countries with limited resources, and mortality from cervical cancer is the most common cause of cancer-related deaths among women in Sub-Saharan Africa. The purpose of this study is to learn about preferences for cervical cancer screening in Zambia, to identify barriers and facilitators for screening uptake, and to evaluate willingness to pay for screening services. Methods/Design We will conduct a discrete choice experiment by interviewing women and men and asking them to choose among constructed scenarios with varying combinations of attributes relevant to cervical cancer screening. To inform the discrete choice experiment, we will conduct focus groups and interviews about general knowledge and attitudes about cervical screening, perception about the availability of screening, stigma associated with cancer and HIV, and payment for health care services. For the discrete choice experiment, we will have a maximum design of 120 choice sets divided into 15 sets of 8 tasks each with a sample size of 320 to 400 respondents. We will use a hierarchical Bayesian estimation procedure to assess attributes at two levels: group and individual levels. The model will generate preferences for attributes to assess the most important features and allow for assessment of differences among cohorts. We will conduct policy simulations reflecting potential changes in the attributes of the screening facilities and calculate the projected changes in preference for selecting to undergo cervical cancer screening. The findings from the discrete choice experiment will be supplemented with interviews, focus groups, and patient surveys to ensure a comprehensive and context-based interpretation of the results. Discussion Because willingness to pay for cervical cancer screening has not been previously assessed, this will be a unique and important contribution to the literature. This study will take into account the high HIV prevalence in Sub-Saharan Africa and prevailing gender attitudes to identify an optimal package of interventions to reduce cervical cancer incidence. This simulation of women’s decisions (and men’s support) to undergo screening will lay the foundation for understanding stated preferences and willingness to pay to help design future screening programs.
Background: Traditional psychological therapies focus mainly on modification of individuals’ conscious decision-making process. Unconscious processes such as cognitive biases have been found to be...
Background: Traditional psychological therapies focus mainly on modification of individuals’ conscious decision-making process. Unconscious processes such as cognitive biases have been found to be accountable for various psychiatric psychopathologies. The advances in technologies have transformed how bias modification programs are being delivered. Objective: We seek to synthesize the current evidence of web-based cognitive bias modification for psychiatric disorders, by identifying the range of conditions targeted and their current efficacy. We wish to determine if web-based attention bias modification is as efficacious as compared to conventional methods. Methods and analysis: A systematic review will be conducted, and all studies types will be included. There will not be any restrictions on the participants included in the study. A search will be conducted on the respective databases up till 2017. Selection of studies will be by the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA-P) guidelines. Quality assessment of the included studies will be assessed using the Cochrane Risk of Bias tool (for randomized trials) and the Newcastle-Ottawa scale for other study designs. A narrative synthesises of the identified articles will be conducted. A meta-analysis will be considered, only if there are sufficient articles in a domain for statistical analysis. Ethical approval for the current protocol and the planned systematic review was not required. Results: Results synthesized would be disseminated using conference presentation or published works in peer-reviewed journals. Conclusions: This review is of importance given how technology transformed the delivery of conventional therapies. The findings from this review will provide guidance for future research involving technology and cognitive bias modification interventions. Registration details: International Prospective Register for Systematic Reviews (PROSPERO) number 2017 CRD42017074754
Background: A diagnosis of cancer in young adulthood can pose many different and unique challenges for individuals. Provision of adequate and appropriate information, care and support for teenagers an...
Background: A diagnosis of cancer in young adulthood can pose many different and unique challenges for individuals. Provision of adequate and appropriate information, care and support for teenagers and young adults around the time of diagnosis is central to their healthcare experience going forward. Appropriate and accessible information provision is critical to ensure young people with cancer feel equipped and empowered to make decisions about, and be involved in, their treatment and recovery throughout their experience; a concept known as prehabilitation. As digital interventions and resources to support TYA with cancer are an increasingly desirable part of healthcare provision, this study will focus on the development of an age and population appropriate (e)lectronic-prehabilitation system of care. Objective: An exploratory, co-design research project will inform the development of an e-Prehabilitation system of care to support Teenagers and Young Adults diagnosed with cancer. A collaborative approach to data collection and prototype design will ensure a patient-centred approach is embedded throughout. Methods: Qualitative, co-design utilising surveys, interviews and focus groups with Teenagers and Young Adults and Health Care Professionals. Results: This research study is in progress; data collection activities have commenced and findings are expected in Summer 2018. Conclusions: The findings from this study will have important implications for informing the future development and evaluation of an e-Prehabilitation system of care to support TYA diagnosed with cancer. Clinical Trial: N/A